HOME >> MEDICINE >> NEWS
Combination therapy does not appear to benefit cardiac patients before heart catheter procedure

Patients with acute myocardial infarction (MI - heart attack) who are referred for percutaneous coronary intervention (such as angioplasty and stent placement in the coronary artery) do not have a reduction in the amount of damaged heart tissue when administered two drugs compared with a single drug to restore blood flow, according to a study in the February 25 issue of The Journal of the American Medical Association (JAMA).

According to background information in the article, "In hospitals with catheterization facilities, primary percutaneous coronary interventions (PCIs) are better then thrombolysis (drug therapy used to dissolve blood clots) in patients with ST-segment elevation acute MI. Specifically designed randomized trials have also shown that patients with acute MI presenting at hospitals without catheterization facilities benefit more from PCI performed after transfer to centers with catheterization laboratories than from on-site thombolysis."

Adnan Kastrati, M.D., from Deutsches Hezzentrum, Technische Universitat, Munich, Germany, and colleagues from the Bavarian Reperfusion Alternatives Evaluation (BRAVE) Study Investigators, assessed whether early administration of the combination of the drugs reteplase plus abciximab produces better reduction of infarct size compared with abciximab alone in patients with acute MI referred for PCI. The study, conducted from May 3, 2001 through June 2, 2003, included 253 patients who were admitted to 13 community hospitals without catheterization facilities (n=186) and to 5 hospitals with catheterization facilities (n=67), within 12 hours of symptoms of an acute MI. Patients randomly received either the combination of reteplase and abciximab (n=125) or abciximab (n=128) alone. All patients were then transferred for PCI. Infarct size was later determined by imaging from a single-photon emission computed tomography (SPECT).

"The final infarct size of the left ventricle, the primary en
'"/>

Contact: Adnan Kastrati, M.D.
kastrati@dhm.mhn.de
JAMA and Archives Journals
24-Feb-2004


Page: 1 2

Related medicine news :

1. Combination treatment helps thyroid cancer patients live longer
2. Combination therapy, not medication alone, most effective for treating children with OCD
3. Combination of erection pill and testosterone gel may benefit men who fail treatment with pill alone
4. Combination therapy w/ ACTOS (pioglitazone HCI) shown to improve components of diabetic dyslipidemia
5. Combination PET/CT should be used to determine stage of non-small cell lung cancer
6. Combination of toxin and poison may be novel treatment for leukemia
7. Combination drug therapy could substantially improve symptoms of rheumatoid arthritis
8. Combination drug therapy offers hope for malaria treatment
9. Combination therapy significantly delays progression of benign prostatic hyperplasia
10. Combination, order of anti-HIV drugs make a difference in first-time recipients
11. Combination of HIV/malaria increases complications during pregnancy

Post Your Comments:
(Date:8/29/2014)... York, (PRWEB) August 29, 2014 ALS, more ... condition that damages the motor neurons in the brain and ... of the nerve cells controlling movement are harmed, which causes ... Eventually this leads to death. , ALS is a disease ... and as many as 30,000 Americans have the disease at ...
(Date:8/29/2014)... 29, 2014 And the results are in! ... & Caicos Islands, is voted a favorite with tourists and ... in the World in the Travelers' Choice Awards on the ... from all across the globe pick their favorites, and the ... in multiple categories. , The Venetian on Grace ...
(Date:8/29/2014)... Reston, VA (PRWEB) August 29, 2014 ... (HHS), Food and Drug Administration (FDA), Center for ... five-year, single-award, indefinite delivery, indefinite quantity (IDIQ) contract ... Operations and Maintenance” and “Development, Modernization and Enhancement ... VersaTech and CRGT. , Overarching contract objectives ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 The Winscribe ... Allen to Chief Executive Officer effective from 1st September ... Officer for Winscribe. , “During this time of growth, ... Greg Allen,” said Matthew Weavers, Winscribe’s Founder and Chairman ... a wealth of commercial, IT and management experience gained ...
(Date:8/28/2014)... Sarasota, FL (PRWEB) August 29, 2014 ... company that brings pharmaceutical industry precision to the ... granted zoning approval for its primary location in ... quickly and decisively with a total commitment to ... look forward to creating," says David Wright, President ...
Breaking Medicine News(10 mins):Health News:Charity Event to Raise Awareness and Donations for the ALS Foundation 2Health News:Team VersaTech and CRGT Win HHS FDA Contract to Support Food Applications Regulatory Management (FARM) System Upgrade 2Health News:Team VersaTech and CRGT Win HHS FDA Contract to Support Food Applications Regulatory Management (FARM) System Upgrade 3Health News:Winscribe Names Greg Allen as CEO 2Health News:Sarasota County Approves Zoning for Leading Medical Cannabis Firm AltMed 2
(Date:8/28/2014)... 28, 2014   Edison Nation Medical , ... worldwide search for product ideas to improve the ... ideas uncovered through the 6-month search ( www.EdisonNationMedical.com/Seniors ... manufacturers and healthcare retailers with whom Edison Nation ... individuals age 65 and older. The ...
(Date:8/28/2014)... , Aug. 28, 2014  In recognition of the ... complications from the flu, pneumonia, shingles and other ... have declared September to be Senior Vaccination Month. ... it is important that adults ages 65 years ... vaccinations. CVS pharmacists and MinuteClinic nurse practitioners and ...
(Date:8/28/2014)... , Aug. 28, 2014  Stryker Orthopaedics, the Official Joint ... bringing its message of joint health to golf fans at ... at the Deutsche Bank Championship. The company,s fan destination – ... Fan Zone on 9" at the TPC Boston in ... th .    At the Deutsche Bank Championship, ...
Breaking Medicine Technology:Edison Nation Medical Launches Open Innovation Search to Uncover Innovative Senior Care Products 2Edison Nation Medical Launches Open Innovation Search to Uncover Innovative Senior Care Products 3September is Senior Vaccination Month at CVS/pharmacy and MinuteClinic 2September is Senior Vaccination Month at CVS/pharmacy and MinuteClinic 3September is Senior Vaccination Month at CVS/pharmacy and MinuteClinic 4Stryker, Official Joint Replacement Products Of The PGA TOUR, Heads To Boston For The Deutsche Bank Championship 2Stryker, Official Joint Replacement Products Of The PGA TOUR, Heads To Boston For The Deutsche Bank Championship 3Stryker, Official Joint Replacement Products Of The PGA TOUR, Heads To Boston For The Deutsche Bank Championship 4Stryker, Official Joint Replacement Products Of The PGA TOUR, Heads To Boston For The Deutsche Bank Championship 5
Cached News: