HOME >> MEDICINE >> NEWS
Combination therapy does not appear to benefit cardiac patients before heart catheter procedure

Patients with acute myocardial infarction (MI - heart attack) who are referred for percutaneous coronary intervention (such as angioplasty and stent placement in the coronary artery) do not have a reduction in the amount of damaged heart tissue when administered two drugs compared with a single drug to restore blood flow, according to a study in the February 25 issue of The Journal of the American Medical Association (JAMA).

According to background information in the article, "In hospitals with catheterization facilities, primary percutaneous coronary interventions (PCIs) are better then thrombolysis (drug therapy used to dissolve blood clots) in patients with ST-segment elevation acute MI. Specifically designed randomized trials have also shown that patients with acute MI presenting at hospitals without catheterization facilities benefit more from PCI performed after transfer to centers with catheterization laboratories than from on-site thombolysis."

Adnan Kastrati, M.D., from Deutsches Hezzentrum, Technische Universitat, Munich, Germany, and colleagues from the Bavarian Reperfusion Alternatives Evaluation (BRAVE) Study Investigators, assessed whether early administration of the combination of the drugs reteplase plus abciximab produces better reduction of infarct size compared with abciximab alone in patients with acute MI referred for PCI. The study, conducted from May 3, 2001 through June 2, 2003, included 253 patients who were admitted to 13 community hospitals without catheterization facilities (n=186) and to 5 hospitals with catheterization facilities (n=67), within 12 hours of symptoms of an acute MI. Patients randomly received either the combination of reteplase and abciximab (n=125) or abciximab (n=128) alone. All patients were then transferred for PCI. Infarct size was later determined by imaging from a single-photon emission computed tomography (SPECT).

"The final infarct size of the left ventricle, the primary en
'"/>

Contact: Adnan Kastrati, M.D.
kastrati@dhm.mhn.de
JAMA and Archives Journals
24-Feb-2004


Page: 1 2

Related medicine news :

1. Combination treatment helps thyroid cancer patients live longer
2. Combination therapy, not medication alone, most effective for treating children with OCD
3. Combination of erection pill and testosterone gel may benefit men who fail treatment with pill alone
4. Combination therapy w/ ACTOS (pioglitazone HCI) shown to improve components of diabetic dyslipidemia
5. Combination PET/CT should be used to determine stage of non-small cell lung cancer
6. Combination of toxin and poison may be novel treatment for leukemia
7. Combination drug therapy could substantially improve symptoms of rheumatoid arthritis
8. Combination drug therapy offers hope for malaria treatment
9. Combination therapy significantly delays progression of benign prostatic hyperplasia
10. Combination, order of anti-HIV drugs make a difference in first-time recipients
11. Combination of HIV/malaria increases complications during pregnancy

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/20/2017)... ... ... Recognising that in today’s busy world consumers are often ... in just three weeks. Setting the groundwork for a healthier lifestyle, Leany Greeny ... work and family schedules, participants can lose up to 15lbs during the program ...
(Date:9/20/2017)... (PRWEB) , ... September 20, 2017 , ... Houston, Texas, ... team took Friday, September 8, and Monday, September 11, off work and rolled up ... Baptist Church before heading to local homes to start the process of rebuilding. , ...
(Date:9/20/2017)... ... September 20, 2017 , ... “The Financial Favor of God; Second Edition”: a ... Second Edition” is the creation of published author, Brooks Rathell. , “We typically hear ... to you about the financial favor of God. Not only does it exist, but ...
(Date:9/19/2017)... ... , ... Only a few physicians were selected to receive the prestigious 2016 ... MD, FACS . The founder and medical director of Clevens Face and Body ... Yale, Harvard and the University of Michigan. He has served patients throughout Central Florida ...
(Date:9/19/2017)... ... September 19, 2017 , ... Peter Chandonait, Abt Associates Principal ... Initiative (PMI) Africa Indoor Residual Spraying (AIRS) Project , has been named the ... to Action Award, a USAID Catalyst Award, recognizes USAID staff and implementing partners ...
Breaking Medicine News(10 mins):
(Date:9/5/2017)... N.J. , Sept. 5, 2017  Getinge, ... has created a vibrant charitable donation program -- ... and support congenital heart defect research by The ... providers and the general public are encouraged to ... and submit the completed artwork to the gallery ...
(Date:9/1/2017)... Michael Penna , President and CEO ... for growth in his response to the July 13, ... seeking a buyer for eMDs. Penna,s company, Complete HealthCare ... Value Added Reseller and national leader in the independent ... "As the healthcare market continues to dictate consolidation, healthcare ...
(Date:8/31/2017)... PM360,s annual Innovations Issue, published in ... innovations happening across the industry. Established six years ago, ... providing a comprehensive look at the newest and most ... innovative companies, startups, divisions, products, services, and strategies from ... "Everyone in this industry wants to do better—in all ...
Breaking Medicine Technology:
Cached News: