Comfort-food cravings may be body's attempt to put brake on chro...( stress response system. This creates a...),Health

From their studies, the researchers concluded that rats with chronically elevated glucocorticoids developed pleasure-seeking/or compulsive behaviors, which included drinking sucrose (rather than saccharine), eating lard, running on the wheel and taking a drug. They then observed changes that took place in the stress response system in the aftermath of eating the comfort food - an increase in abdominal fat and an end to corticotropin releasing factor and adrenocorticotropin secretion. They also observed an inverse relationship between abdominal fat and the expression of genes in the motor zone of the hypothalamus, where the stress response is initiated.

"This seems to be the body's way of telling the brain, 'It's ok, you can relax, you're refueled with high-energy food,'" says Pecoraro. The message is clearly being transmitted in the middle-aged man or woman with a gut. "This body type represents the classic distribution of fat from stress." The new model may explain why losing weight is notoriously difficult, he says. Losing weight is literally stressful, which makes a person feel anxious, and stress hormones make a person crave high energy foods, which blunt the feelings of stress and make one feel better.

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Contact: Jennifer OBrien
jobrien@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
10-Sep-2003