Compound That Mimics Insulin Might Lead To Pill For Diabetes, As Reported In The 7 May Issue Of Science

Washington DC - Diabetics may someday pop a pill to control their disease, now that scientists have discovered a compound that might make such a pill effective. This new substance, whose discovery is reported in the 7 May issue of Science, appears to mimic the effects of insulin, at least in mice--but, unlike insulin, it can be swallowed instead of injected. A pill developed from this substance could be a welcome alternative to the insulin injections or rigorous lifestyle monitoring that are currently part of a diabetic's daily life.

Diabetes occurs when the body's cells are unable to absorb enough blood sugar, or glucose, to fuel their activities. To access this energy supply, cells need assistance from the hormone insulin, which kicks off a complex series of steps inside the cells that allows them to store and use glucose. This cascade of events doesn't occur-or occurs poorly-in diabetics, either because their bodies don't produce insulin (type I diabetes), or because they are resistant to its effects (type II). An oral drug that could trigger the same set of reactions in place of insulin could therefore be a boon for people with either form of the disease.

In order to avoid or delay the serious complications their disease can cause, diabetics must carefully control their blood sugar levels-currently a high-maintenance task. People with the early-onset and more severe type I diabetes need as many as four daily injections of insulin. And people with type II diabetes, who are usually over 40 or overweight, must carefully regulate their diet, weight, and physical activity. About 10% of the population in the Western world develops some degree of type II diabetes, so a pill that made the disease easier to manage could have a widespread benefit.

The research team, whose members are from the US, Spain, and Sweden, screened over 50,000 different compounds to see if any of them might perform as a stand-in for insulin. The compound would have to bin

Contact: Gabriel Paal
American Association for the Advancement of Science

Page: 1 2 3

Related medicine news :

1. Compound may help prevent diabetes in fast-food fans
2. Compound in apples may help fight Alzheimers disease
3. Compound in salsa may fight food poisoning
4. Compound shows promise as vaccine-like drug for preventing type 1 diabetes
5. Compound developed from mussels may lead to safer, more effective medical implants
6. Compounds also present in alcoholic beverages may explain chocolate cravings
7. Alga-Based Compound Promises Less Bleeding On The Battlefield
8. Compound In Meat Prevents Diabetes, Study Suggests
9. Researchers Synthesize Compounds For New Class Of Antibiotics
10. Cancer Protection Compound Abundant In Broccoli Sprouts
11. Scientists Produce New Anti-Malarial Compound

Post Your Comments:

(Date:10/8/2019)... ... October 08, 2019 , ... Cognosante has ... Department of Veterans Affairs Community Care Referrals and Authorizations program. The new task ... Health Share Referral Manager (HSRM), an enterprise-wide system used by community care staff ...
(Date:10/8/2019)... COLLEGE PARK, Md. (PRWEB) , ... October 08, ... ... to observe fungal infection progression in live samples, Meiqing Shi, associate professor with ... in the field. In his latest paper published in Nature Communications, Shi and ...
(Date:10/8/2019)... , ... October 08, 2019 , ... Over the past ... as a standout in the sports restaurant category by providing a higher-quality product and ... new fall menu as well as a "RAISE A MUG FOR THE CAUSE" campaign ...
(Date:10/8/2019)... ... 08, 2019 , ... METAvivor Research and Support Inc., a non-profit organization dedicated ... Stage IV Stampede campaign. The campaign will commence with two days of action and ... advocacy boot camp, a march, a Die-In (hosted by partner MET-UP), and visits with ...
(Date:10/8/2019)... FAYETTEVILLE, Ark. (PRWEB) , ... October 08, 2019 ... ... Hub has selected CardioWise, Inc. a Digital Health Awards 1st Round ... of UCSF Digital Health Awards was to select companies that promote faster, better, ...
Breaking Medicine News(10 mins):
(Date:10/19/2019)... Conn. (PRWEB) , ... October 19, 2019 , ... Hospital ... of 2019, according to new acquisition data from HealthCareMandA.com. The most recent quarter was ... Dollar volume was up sharply compared with the second quarter, totaling nearly $5.0 billion, ...
(Date:10/17/2019)... ... October 17, 2019 , ... Women’s concern in the wake of the ... implants is the subject of a September 24 article on CBS Miami. ... the Allergan recall has revived a number of issues, including a possible link between ...
(Date:10/15/2019)... ... October 14, 2019 , ... ... linearity and calibration verification kit, for Roche cobas® analyzers, Order No. 507ro. ... B (Apo-B). Each VALIDATE® LP2 kit, liquid, ready-to-use, and prepared using ...
Breaking Medicine Technology:
Cached News: