HOME >> MEDICINE >> NEWS
Computer design yields better, more efficient therapeutic for preventing tissue damage

ree-dimensional structure of Compstatin in solution via nuclear magnetic resonance (NMR) experiments, which he then computationally refined.

The computational de novo protein design system, developed at Princeton University by Floudas and postdoctoral associate John Klepeis, is a technological advance made possible by (i) a novel mixed-integer optimization model that narrows 200 trillion amino acid sequences into a short list of candidates that are likely to produce a peptide of the desired shape, and (ii) a system called ASTRO-FOLD that, using first-principles, predicts the structures that would be formed by the candidate sequences. The second step confirms and refines the first.

A distributed computing environment consisting of eighty Linux-based computers was used for all the computational predictions, and the predicted new peptides were subsequently synthesized and experimentally validated in the Lambris laboratory at Penn.


'"/>

Contact: Greg Lester
lesterg@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
25-Aug-2003


Page: 1 2 3

Related medicine news :

1. Computerized order entry systems can increase risk of medication errors
2. Computer model being developed at Stanford may help surgeons better predict patient outcomes
3. Computer memory, MRI technology benefit from student research at UH
4. Computer program helps doctors diagnose lung cancer
5. Computer simulation shows how fibrils form
6. Computer reads heart condition from X-ray images
7. Computer assisted standing orders improve adult immunization rates
8. Computerized orders effective in increasing administration of influenza and pneumococcal vaccines
9. Computer system makes chain of health care stronger, safer
10. Computer prescribing systems risk patient safety
11. Computerized prescriber order entry systems may have limited impact on patient harm

Post Your Comments:
(Date:7/2/2015)... ... July 02, 2015 , ... Get ready to hit ... SOCKS. Since the socks were first introduced, they have rapidly been gaining attention ... inspired four new, fun shades including: blue, lime, pink and red. , ...
(Date:7/2/2015)... ... July 02, 2015 , ... The ZAC Foundation, a national ... season with important lessons on how to stay water safe with the help of ... Swim, authored by The ZAC Foundation co-founders, follows Zeke’s water safety journey. Zeke, ...
(Date:7/2/2015)... ... July 02, 2015 , ... ... (NPWT) - pipeline review 2015” provides comprehensive information on the pipeline products ... report on negative pressure wound therapy (NPWT) with 22 market data tables ...
(Date:7/2/2015)... ... July 02, 2015 , ... ... them with care and precision. There is an art and science that goes ... honor of successfully reshaping the facial features and lives of more than 2,500 ...
(Date:7/2/2015)... ... July 02, 2015 , ... ... consulting services to the federal government, has announced they are among nine contractors ... Management Office Support Services (BMOSS) contract not to exceed $250 million. , ...
Breaking Medicine News(10 mins):Health News:SIGVARIS is Sporting Four Brand New Colors in the Popular PERFORMANCE SOCK Product Line 2Health News:The ZAC Foundation Kicks Off Summer and July 4th Weekend with Complimentary Children’s E-Book on Water Safety 2Health News:The ZAC Foundation Kicks Off Summer and July 4th Weekend with Complimentary Children’s E-Book on Water Safety 3Health News:Negative Pressure Wound Therapy (System, Wound Care, Tissue Cooling NPWT) Pipeline Review 2015 Market Research Report Available at RnRMarketResearch.com 2Health News:Negative Pressure Wound Therapy (System, Wound Care, Tissue Cooling NPWT) Pipeline Review 2015 Market Research Report Available at RnRMarketResearch.com 3Health News:Negative Pressure Wound Therapy (System, Wound Care, Tissue Cooling NPWT) Pipeline Review 2015 Market Research Report Available at RnRMarketResearch.com 4Health News:Dr. Kevin Sadati Featured in July Issue of Popular National Magazines 2Health News:Dr. Kevin Sadati Featured in July Issue of Popular National Magazines 3Health News:Octo Consulting Group Awarded IDIQ Contract for SEC Business Management Support 2
(Date:7/2/2015)... , July 2, 2015 ... (Homofermentative & Heterofermentative), Species (Lactobacillus, Pediococcus & Enterococcus), Enzymes ... and Forecast to 2020", Silage Inoculants & Enzymes Market ... a CAGR of 4.0% from 2015 to 2020. ... igures spread through 194 P ...
(Date:7/2/2015)...  The Commission for Certification in Geriatric Pharmacy ... that represents pharmacists in acute and ambulatory settings, ... for recertification of Certified Geriatric Pharmacists.  ASHP will ... this purpose.  ASHP will join the American Society ... CCGP Professional Development Program. ...
(Date:7/2/2015)... 2015 BGI announced today that its high-throughput ... has been accredited by the American College of ... clinical next-generation-sequencing laboratory to receive the CAP certification in ... in clinical laboratory practices. Complementary to the exiting US FDA ... multiple ISO certifications, the CAP certification enables BGI to ...
Breaking Medicine Technology:Silage Inoculants & Enzymes Market Worth $489.05 Million by 2020 2Silage Inoculants & Enzymes Market Worth $489.05 Million by 2020 3Silage Inoculants & Enzymes Market Worth $489.05 Million by 2020 4Commission for Certification in Geriatric Pharmacy Adds ASHP as Professional Development Program Provider 2BGI Receives Accreditation from the College of American Pathologists (CAP) 2
Cached News: