HOME >> MEDICINE >> NEWS
Computer design yields better, more efficient therapeutic for preventing tissue damage

ree-dimensional structure of Compstatin in solution via nuclear magnetic resonance (NMR) experiments, which he then computationally refined.

The computational de novo protein design system, developed at Princeton University by Floudas and postdoctoral associate John Klepeis, is a technological advance made possible by (i) a novel mixed-integer optimization model that narrows 200 trillion amino acid sequences into a short list of candidates that are likely to produce a peptide of the desired shape, and (ii) a system called ASTRO-FOLD that, using first-principles, predicts the structures that would be formed by the candidate sequences. The second step confirms and refines the first.

A distributed computing environment consisting of eighty Linux-based computers was used for all the computational predictions, and the predicted new peptides were subsequently synthesized and experimentally validated in the Lambris laboratory at Penn.


'"/>

Contact: Greg Lester
lesterg@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
25-Aug-2003


Page: 1 2 3

Related medicine news :

1. Computerized order entry systems can increase risk of medication errors
2. Computer model being developed at Stanford may help surgeons better predict patient outcomes
3. Computer memory, MRI technology benefit from student research at UH
4. Computer program helps doctors diagnose lung cancer
5. Computer simulation shows how fibrils form
6. Computer reads heart condition from X-ray images
7. Computer assisted standing orders improve adult immunization rates
8. Computerized orders effective in increasing administration of influenza and pneumococcal vaccines
9. Computer system makes chain of health care stronger, safer
10. Computer prescribing systems risk patient safety
11. Computerized prescriber order entry systems may have limited impact on patient harm

Post Your Comments:
(Date:8/29/2015)... ... August 29, 2015 , ... Next weekend is Labor Day weekend, ... officially ends on September 22nd this year). For IT security personnel, it should also ... which could prove far more costly than a simple headache. , Joe Caruso, founder ...
(Date:8/29/2015)... ... 29, 2015 , ... People who have heart or lung ... asthma, are at higher risk from wildfire smoke especially in Calgary, Alberta.Those with ... problems (arrhythmia or irregular heartbeat) are also sensitive to air pollution. , ...
(Date:8/29/2015)... ... August 29, 2015 , ... The popular television program ... Jones, recently announced that it will be devoting an entire short segment to the ... of people around the globe on a daily basis, but recent advancements in medical ...
(Date:8/28/2015)... ... August 29, 2015 , ... Rio Salado College joined ... student experience as part of the EDUCAUSE - Next Generation Learning Challenges 2015 Breakthrough ... is the third Breakthrough Models Incubator hosted by EDUCAUSE and NGLC, which ...
(Date:8/28/2015)... ... ... An online provider of CPAP machines, masks, supplies, and accessories, My Cpap ... by offering shipping at no cost to you, directly to your door on all ... My Cpap Store is located in Las Vegas, Nevada. , Sleep apnea is a ...
Breaking Medicine News(10 mins):Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 2Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 3Health News:Business Cyber Security – Come Out of the Summer with a Clean Slate 4Health News:Heart Fit Clinic Sounds the Alarm on Forest Fire Smoke and Chronic Heart Disease in Calgary Area 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 3Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 4Health News:My Cpap Store Now Offering Delivery Special 0 Cost to You 2
(Date:8/28/2015)... and LONDON , August 28, 2015 ... approach seamlessly connects people, technologies ... improving outcomes and the cost of ... PHG AEX: PHIA) today announced its presence at  ESC Congress ... solutions, including Heart Model A.I. , EchoNavigator and IntelliSpace Cardiovascular, ...
(Date:8/27/2015)... , Aug. 27, 2015  A recent study ... Knee Journal, compared the Arthrosurface HemiCAP® Wave implant, ... versus an "onlay" design implant for isolated patellofemoral ... in function and pain scores, none of the ... osteoarthritis (OA). However, 53% of the patients in ...
(Date:8/27/2015)... Aug. 27, 2015 ieCrowd™ today announced ... commercial development of the company,s supplemental oxygen delivery ... device, being developed by ieCrowd,s subsidiary Smart Oxygen ... changing demand for oxygen based on level of ... submission for the Smart Oxygen device would require ...
Breaking Medicine Technology:Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 2Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 3Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 4Study Demonstrates Dramatic Reduction in Progression of Osteoarthritis with the Arthrosurface "Inlay" Patellofemoral Implant Design Compared to Traditional "Onlay" Implant 2Study Demonstrates Dramatic Reduction in Progression of Osteoarthritis with the Arthrosurface "Inlay" Patellofemoral Implant Design Compared to Traditional "Onlay" Implant 3Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 2Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 3Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 4
Cached News: