HOME >> MEDICINE >> NEWS
Computer design yields better, more efficient therapeutic for preventing tissue damage

ree-dimensional structure of Compstatin in solution via nuclear magnetic resonance (NMR) experiments, which he then computationally refined.

The computational de novo protein design system, developed at Princeton University by Floudas and postdoctoral associate John Klepeis, is a technological advance made possible by (i) a novel mixed-integer optimization model that narrows 200 trillion amino acid sequences into a short list of candidates that are likely to produce a peptide of the desired shape, and (ii) a system called ASTRO-FOLD that, using first-principles, predicts the structures that would be formed by the candidate sequences. The second step confirms and refines the first.

A distributed computing environment consisting of eighty Linux-based computers was used for all the computational predictions, and the predicted new peptides were subsequently synthesized and experimentally validated in the Lambris laboratory at Penn.


'"/>

Contact: Greg Lester
lesterg@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
25-Aug-2003


Page: 1 2 3

Related medicine news :

1. Computerized order entry systems can increase risk of medication errors
2. Computer model being developed at Stanford may help surgeons better predict patient outcomes
3. Computer memory, MRI technology benefit from student research at UH
4. Computer program helps doctors diagnose lung cancer
5. Computer simulation shows how fibrils form
6. Computer reads heart condition from X-ray images
7. Computer assisted standing orders improve adult immunization rates
8. Computerized orders effective in increasing administration of influenza and pneumococcal vaccines
9. Computer system makes chain of health care stronger, safer
10. Computer prescribing systems risk patient safety
11. Computerized prescriber order entry systems may have limited impact on patient harm

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/29/2017)... ... March 29, 2017 , ... AngioGenesis Labs sold 300 ... Mississippi. AngioGenesis Labs, makers of HeartBoost, BrainBest and BeautyBest, achieved these results while ... HeartBoost, an over the counter heart healthy drink, can reduce Arterial Plaque, Lower ...
(Date:3/29/2017)... ... March 29, 2017 , ... Dr. Angela Cotey, a ... treatment and accepting new pediatric patients, with or without a referral. Dr. Cotey knows ... a better orthodontic outcome and experience. When patients receive early treatment, they may achieve ...
(Date:3/29/2017)... ... March 29, 2017 , ... Curio Wellness , a premium medical cannabis ... the company’s executive management team with prominent executives from both inside and outside the ... Operating Officer, Ted Dumbauld , who has more than twenty years of business ...
(Date:3/29/2017)... Yorba Linda, Ca (PRWEB) , ... March 29, 2017 , ... ... treatment of a growing number of cancers and is touted to be the next ... of treatment, thus far, has been in the form of immune checkpoint inhibitors such ...
(Date:3/29/2017)... ... , ... The Wharton School of the University of Pennsylvania is pleased to ... $10 million gift to establish the Ken Moelis and Julie Taffet Moelis Advance ... Wharton MBA for highly-qualified Penn undergraduates whose academic and career interests expand traditional notions ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... NEW YORK , March 29, 2017 ... ... society and the public safety in regulating marijuana, but economic ... revenues, job creation, and reduced law enforcement costs. However, to ... like those provided by SinglePoint, Inc. (OTC: SING) ( SING ...
(Date:3/29/2017)... , March 29, 2017 /PRNewswire/ - Medicure Inc. ("Medicure") ... financial results for the year ended December 31, ... 2017. The results are being released later than ... statements will include the operations and balances of ... 2016.  This release and filing date meets TSX ...
(Date:3/28/2017)... The global emerging cancer diagnostics market is ... 2016 to 2023 and reach a figure of $6.34 ... a chronic disease and is affecting a huge population. ... This report is focused on emerging cancer diagnostics market ... propelled due to factors such as: increasing number of ...
Breaking Medicine Technology:
Cached News: