HOME >> MEDICINE >> NEWS
Dartmouth researchers advance fight against pancreatic cancer

LEBANON, NH -- Two Dartmouth medical studies have produced promising results in the fight against pancreatic cancer, one of the most deadly and aggressive forms of cancer, and may lead to the development of new, highly targeted therapies to manage previously untreatable tumors.

In two trials targeting some of the most challenging traits of pancreatic tumor cell growth, researchers from Dartmouth Medical School (DMS) and the Norris Cotton Cancer Center (NCCC) at Dartmouth-Hitchcock Medical Center (DHMC) have demonstrated success in slowing and preventing tumor development.

The NCCC research team was led by Dr. Murray Korc, a pioneer in early research on growth factor receptors in pancreatic cancer, and chair of the department of medicine at DMS and DHMC. An endocrinologist and cancer biologist, he focuses much of his research on the mechanisms that make pancreatic cancer so resilient and aggressive. Work reported in the May 15 issues of Clinical Cancer Research and Cancer Research addresses the team's latest advances.

Pancreatic cancer is characteristic for its ability to spread quickly, while becoming increasingly resistant to traditional chemotherapy. Generally diagnosed in an advanced state, it is frequently inoperable. As a result, it is the fourth leading cause of cancer death in adults in the US, killing more than 30,000 Americans every year, says Korc.

"By the time the disease is diagnosed, pancreatic cancer cells have a huge growth advantage over normal cells, which enables them to grow and metastasize very quickly," said Korc. "Our research has focused on determining what factors enable the cells to grow at such a fast rate and then how to slow that rate down and actually suppress pancreatic tumor growth."

Korc likens the disease to speeding in a car with an accelerator that is stuck to the floor. "Naturally, you apply the brakes but they don't work, so you begin pumping the brakes to slow the car down. The brak
'"/>

Contact: Andy Nordhoff
DMS.Communications@Dartmouth.edu
603-653-1969
Dartmouth Medical School
15-May-2004


Page: 1 2 3

Related medicine news :

1. Dartmouth researchers find where musical memories are stored in the brain
2. Dartmouth awarded $21.8 million NSF grant
3. Dartmouth Medical School receives $1.6 million in AIDS funding
4. Dartmouth study suggests caution against using certain drugs to unclog heart arteries
5. Gender and geography increase racial disparities in health care, Dartmouth study shows
6. Dartmouth/VA study questions screening priorities of prostate and colon cancer
7. Dartmouth researcher Michael B. Sporn, M.D. honored for pioneering work in cancer prevention
8. Dartmouth/VA researchers examine news coverage of breast cancer prevention
9. Dartmouth researchers question use of tobacco funds
10. Dartmouth team finds uneven relationship between newborn intensive care and death rates
11. Dartmouth hosts International Ewings Sarcoma Symposium

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/22/2017)... ... September 22, 2017 , ... ... Pennsylvania, is pleased to offer in-home and online newborn sleep consultations . ... has on the body,” says company owner Courtney Zentz, a pediatric sleep professional, ...
(Date:9/22/2017)... ... ... “Cursed with a Curse: The Truth about Tithing”: a ... when breaking free from this misconception. “Cursed with a Curse: The Truth about ... Christian Faith Publishing, Lysa M. Harrison’s new book is a powerful and thought-provoking ...
(Date:9/22/2017)... ... 22, 2017 , ... Silicon Valley startup Enke Life has ... Their electric toothbrushes aggressively attack oral bacteria by reducing dental plaque and other ... edge Enke technology with a premium timeless design, they want to redefine the ...
(Date:9/22/2017)... ... September 22, 2017 , ... Egg freezing and embryo ... embryos have a slight statistical advantage for live births, frozen eggs offer many ... for women undergoing medical treatment or who are concerned about the decline of ...
(Date:9/21/2017)... ... September 21, 2017 , ... Process ... 1:30 p.m. – 3:00 p.m. ET, http://www.fdanews.com/processcapabilityindices      , ... wrong, run afoul of The Quality System Regulation (§820.250), and Devicemakers find themselves ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)... 7, 2017  Eli Lilly and Company (NYSE: ... streamline operations to more efficiently focus resources on ... structure. Global workforce reductions, including those from a ... impact approximately 3,500 positions. With ... savings of approximately $500 million that will begin ...
(Date:9/7/2017)... Ind. , Sept. 7, 2017  Zimmer Biomet ... in musculoskeletal healthcare, today announced that it will be ... Global Healthcare Conference at the Grand Hyatt hotel in ... 11, 2017 at 11:40 a.m. Eastern Time. ... via Zimmer Biomet,s Investor Relations website at http://investor.zimmerbiomet.com ...
(Date:9/6/2017)... ORANGEBURG, N.Y. , Sept. 6, 2017   PDI ... today announced it will host an educational session focused ... line-associated bloodstream infection (CLABSI) prevention at the 2017 Annual ... meeting, which will take place at the ... Arizona from Sept. 16-19, will also feature ...
Breaking Medicine Technology:
Cached News: