The Effect of ADDERALL XR Treatment on Driving Performance in Young Adults with ADHD (USPMHC Poster # 316).
This preliminary, six-week study suggested that patients taking ADDERALL XR demonstrated a significant improvement in driving performance compared to placebo, as measured by their Driving Safety Score (DSS), which was derived from safety related driving parameters using the STISIM Driving Simulator. In addition, the data revealed that ADDERALL XR significantly improved driving safety scores at 7 hours and 12 hours after taking medication. Patients taking ADDERALL XR also demonstrated a significant improvement in cognitive functioning compared to placebo, as assessed by the CogScreen-Aeromedical Edition (AE) Aviator Predictor Score (APS), which was derived from a computerized test developed for the Federal Aviation Administration to measure the cognitive functioning (e.g., multi-tasking ability, information processing, etc.) of pilots.
Furthermore, 80 percent of patients experienced a 30 percent reduction in their ADHD Rating Scale (ADHD-RS) score when taking ADDERALL XR, signifying an overall improvement in ADHD symptoms, while only 13 percent of patients achieved this level of symptom improvement when receiving placebo (P=0.0004).
About the Study
During the six-week study period, investigators randomized 19 patients aged 19 to 25 years to receive three weeks of active treatment with ADDERALL XR or treatment with placebo in a crossover design. All patients were diagnosed with ADHD using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR
Contact: Dr. Gary Kay, Washington Neuropsychological Institute