HOME >> MEDICINE >> NEWS
Depression may explain higher risk of heart attack associated with antidepressants

The underlying depression, rather than the effects of the drugs themselves, may explain the increased risk of heart attack associated with taking antidepressants, suggests research in Heart. More than one in 10 older people are prescribed antidepressants.

The findings are based on anonymous prescribing supplied from 644 general practices across the UK, on 60,000 patients who had had their first heart attack between 1998 and 2001 and 360,000 randomly selected others, matched for age and sex.

Analysis indicated an increased risk of a first heart attack with either the newer or older class of antidepressants within the first month of prescription.

Patients who had been prescribed the older class of tricyclic antidepressants (TCAs) for the first time were twice as likely to have a heart attack within the next seven days as patients who had not been prescribed these drugs.

And patients prescribed the newer class of selective serotonin reuptake inhibitors (SSRIs) were over twice as likely to have a heart attack within the next seven days.

But the increased risks of a heart attack were much lower among patients who took antidepressants for longer than a month. These risks disappeared after taking account of the extent of existing cardiovascular disease and depression, which was gleaned from looking at the prescription data before and after the heart attack (known as self controlled analysis).

The authors also failed to find any link with specific antidepressants or with the class of drug, leading them to conclude that any increase in heart attack risk is more likely to be linked to the underlying depression rather than the drugs themselves.


'"/>

Contact: Emma Dickinson
edickinson@bmj.com
44-0-207-383-6529
BMJ Specialty Journals
14-Mar-2005


Page: 1

Related medicine news :

1. Depression linked to insomnia in HIV patients
2. Depression predicts heart rhythm abnormalities in heart attack patients
3. Depression caused by common treatment for hepatitis C may affect outcome
4. Depression tied to higher risk of heart disease death
5. Depression predicts mortality in women with heart disease
6. Depression can lead to back pain
7. Depression on College Campuses conference
8. Depression may be a risk factor for heart disease, death in older women
9. Depression, other psychiatric illnesses common following traumatic brain injury
10. Depression, trauma stress linked to physical complaints
11. Depression doubles risk of death after bypass surgery

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/9/2020)... ... April 09, 2020 , ... Wanda Health announces the ... the company’s COVID-19 Telehealth programs. The Wanda Health programs are helping to provide ... the risk of exposure to their medical staff during the COVID-19 pandemic. ...
(Date:4/7/2020)... ... April 07, 2020 , ... With water ... employing plans to prevent service disruptions and assist households struggling to pay water ... Water Works Association (AWWA). , Ninety-seven percent of the 532 responding utilities ...
(Date:4/5/2020)... ... ... Given the current pandemic and economic crisis, it is important to manage ... rise to several thousand dollars per year. It all depends on several factors, including ... so on. Drivers can get better rates if they: , , ...
(Date:4/2/2020)... ... April 02, 2020 , ... ... their mother’s womb are encouraging their parents, grandparents, and guardians, to file a ... to $6 billion in funds will be made available by Purdue as part ...
(Date:4/1/2020)... ... April 01, 2020 , ... Velocidy Bio ’s Dutch biotech ... NEXTGENPCR that decreases the testing time for SARS-CoV-2 to eight minutes, compared to ... size of a shoebox could perform a hundred and eighty (180) amplification runs a ...
Breaking Medicine News(10 mins):
(Date:4/7/2020)... ... April 07, 2020 , ... Ziegler, a ... (PHC) on its investment by Council Capital (Council). PHC is the leading provider ... current footprint in surrounding states. PHC will use this investment to fund its ...
(Date:4/7/2020)... RATON, Fla. (PRWEB) , ... April 07, 2020 , ... ... Emergent Care , The Coronavirus pandemic means health care providers are adopting radical precautions ... Center has ceased all procedures except those of an urgent or emergency nature. Brent ...
(Date:4/5/2020)... ... April 05, 2020 , ... INTRODUCTION , As the world’s ... of COVID-19[1], we are committed to the non-profit dissemination of our COVID-19 discoveries ... post-entry suppression of ACE2 mRNA expression in host cells is one of our ...
Breaking Medicine Technology:
Cached News: