HOME >> MEDICINE >> NEWS
Detecting vitamin B12 deficiency prevents anaemia and memory loss

Vitamin B12 is essential to human life. The body cannot make its own supplies and without an adequate dietary supply from animal sources or enriched cereals, up to 20 million people can suffer anaemia, risk nerve damage and even death. Unfortunately, vitamin B12 deficiency can go undetected for several years, remaining invisible to doctors while the likelihood of irreversible cell damage increases.

Under EUREKA project E! 2263 HOLOTC, Norwegian diagnostics company Axis Shield teamed up with Danish academics to find a way to pick up early warning signs of potentially harmful B12 deficits. The project pioneered a unique B12 detection system, which tracks concentrations of holotc (short for holo-transcobalamin), a biologically active complex of the vitamin plus a carrier protein. Although the holotc complex carries only 20% of the body's vitamin B12, the other 80% is not nearly as significant since it is effectively not available for uptake by the cells. Current diagnostic techniques measure the total amount of B12 in the blood. Because these tests do not discriminate between holotc and the inactive vitamin, they can misleadingly return a healthy result for patients with too little active B12.

Lars Orning, the Project Manager from Axis Shield, says "current methods are technically good, but have low diagnostic sensitivity. The HOLOTC test isolates vitamin B12, enabling early identification of patients with B12 malabsorption."

HOLOTC is well on the way to producing a simple, automated, adaptable radio immunoassay which the partners expect will take the largest share of the world market for vitamin B12 diagnostic tests.

Ebba Nexo of University Hospital of Aarhus, Denmark, describes how until recently it has not been possible to develop suitable methods to measure holotc. "The early detection of this key indicator has allowed our laboratories to develop measurement prototypes." As a result, "HOLOTC is well on the road to producing simple,
'"/>

Contact: Julie Sors
julie.sors@es.eureka.be
32-2-777-0969
EUREKA
4-Mar-2004


Page: 1 2

Related medicine news :

1. Detecting breast cancer spread by white light - groundbreaking technology
2. Detecting Alzheimers
3. Scientists Create Extremely Sensitive Test For Detecting Radiation Damage
4. Not enough evidence that multivitamins prevent infections in the elderly
5. Folic acid and vitamin B12 decrease risk of hip fracture in stroke patients
6. Calcium and vitamin D most effective for treatment of Crohns-related bone loss
7. High doses of vitamin E supplements do more harm than good
8. Study shows high-dose vitamin E supplements may increase risk of dying
9. Center refutes finding that added sugars displace vitamins and minerals
10. Study showed vitamin D inadequacy highly prevalent among women treated for osteoporosis
11. Novel vitamin discovery offers clues for cancer chemotherapy and lipid disorders

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to Best ... individuals in the United States and Canada wear eyeglasses. Once considered to be a ... and make a fashion statement. Even celebrities use glasses as a way of creating ...
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a ... can give their videos a whole new perspective by using the title layers ... Film Studios. , ProSlice Levels contains over 30 Different presets to choose from. ...
(Date:6/26/2016)... Clarkston, Michigan (PRWEB) , ... June 26, 2016 ... ... respect to fertility once they have been diagnosed with endometriosis. These women need ... but they also require a comprehensive approach that can help for preservation of ...
(Date:6/25/2016)... , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on ... Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ability ... fumigation is not a common occurrence, but a necessary one in the event that lice ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern ... Laude and his M.D from the David Geffen School of Medicine at UCLA. He ... Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... and INDIANAPOLIS , June 23, ... a Lilly Diabetes Tomorrow,s Leaders Scholarship is any indication, ... winners, announced today online at www.diabetesscholars.org by ... 1 diabetes stand in the way of academic and ... the Foundation,s scholarship program since 2012, and continues to ...
(Date:6/23/2016)... N.J. , June 23, 2016  Guerbet announced ... Premier Inc.,s Supplier Horizon Award . ... year, Guerbet was recognized for its support of Premier ... creation through clinical excellence, and commitment to lower costs. ... to receive this recognition of our outstanding customer service ...
(Date:6/23/2016)... 23, 2016  Experian Health, the healthcare ... the patient payment and care experience, today ... products and services that will enhance the ... offerings. These award-winning solutions will enable healthcare ... compliant in an ever-changing environment and redefine ...
Breaking Medicine Technology:
Cached News: