HOME >> MEDICINE >> NEWS
Detecting vitamin B12 deficiency prevents anaemia and memory loss

Vitamin B12 is essential to human life. The body cannot make its own supplies and without an adequate dietary supply from animal sources or enriched cereals, up to 20 million people can suffer anaemia, risk nerve damage and even death. Unfortunately, vitamin B12 deficiency can go undetected for several years, remaining invisible to doctors while the likelihood of irreversible cell damage increases.

Under EUREKA project E! 2263 HOLOTC, Norwegian diagnostics company Axis Shield teamed up with Danish academics to find a way to pick up early warning signs of potentially harmful B12 deficits. The project pioneered a unique B12 detection system, which tracks concentrations of holotc (short for holo-transcobalamin), a biologically active complex of the vitamin plus a carrier protein. Although the holotc complex carries only 20% of the body's vitamin B12, the other 80% is not nearly as significant since it is effectively not available for uptake by the cells. Current diagnostic techniques measure the total amount of B12 in the blood. Because these tests do not discriminate between holotc and the inactive vitamin, they can misleadingly return a healthy result for patients with too little active B12.

Lars Orning, the Project Manager from Axis Shield, says "current methods are technically good, but have low diagnostic sensitivity. The HOLOTC test isolates vitamin B12, enabling early identification of patients with B12 malabsorption."

HOLOTC is well on the way to producing a simple, automated, adaptable radio immunoassay which the partners expect will take the largest share of the world market for vitamin B12 diagnostic tests.

Ebba Nexo of University Hospital of Aarhus, Denmark, describes how until recently it has not been possible to develop suitable methods to measure holotc. "The early detection of this key indicator has allowed our laboratories to develop measurement prototypes." As a result, "HOLOTC is well on the road to producing simple,
'"/>

Contact: Julie Sors
julie.sors@es.eureka.be
32-2-777-0969
EUREKA
4-Mar-2004


Page: 1 2

Related medicine news :

1. Detecting breast cancer spread by white light - groundbreaking technology
2. Detecting Alzheimers
3. Scientists Create Extremely Sensitive Test For Detecting Radiation Damage
4. Not enough evidence that multivitamins prevent infections in the elderly
5. Folic acid and vitamin B12 decrease risk of hip fracture in stroke patients
6. Calcium and vitamin D most effective for treatment of Crohns-related bone loss
7. High doses of vitamin E supplements do more harm than good
8. Study shows high-dose vitamin E supplements may increase risk of dying
9. Center refutes finding that added sugars displace vitamins and minerals
10. Study showed vitamin D inadequacy highly prevalent among women treated for osteoporosis
11. Novel vitamin discovery offers clues for cancer chemotherapy and lipid disorders

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Detecting vitamin deficiency prevents anaemia and memory loss

(Date:1/22/2015)... For over 20 years, Dr. David Cruz of ... area has treated just about every type of injury that can ... for those same twenty-plus years, the team at Doctors on ... the best possible doctor. With the combined breadth of ...
(Date:1/22/2015)... 2015 Joan Lunden, award-winning American journalist, ... the upcoming 32nd Annual Miami Breast Cancer Conference ... Resource®, LLC (PER®) , shares that “a fast-growing, virulent” ... if she had not followed up her clean mammogram ...
(Date:1/22/2015)... 22, 2015 Yesterday, Senator Holly ... and Kristin Olsen (R-Modesto) were honored by the ... advancing biotechnology, biomedical science, medical device and pharmaceutical ... received the “2014 Life Sciences Champion” award from ...
(Date:1/22/2015)... Florida (PRWEB) January 22, 2015 IsoComforter, Inc. ... therapy machine with patented IsoTube design to treat specific body ... introduced the most progressive and easy to use patented cold ... post-operative and sports related orthopedic and muscle injuries. IsoComforter ...
(Date:1/22/2015)... January 22, 2015 Payday lending practices ... communities and cause financial distress to the states that ... at Howard University’s Center on Race and Wealth. , ... economic activity, payday loans at the same time substantially ...
Breaking Medicine News(10 mins):Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2
(Date:1/23/2015)... , Jan. 23, 2015 A lot of discussion in ... for treating  certain illnesses, injuries, or conditions. As medical science ... treatment methods with ones that they consider to be more ... is not one textbook method of treatment that stands out ...
(Date:1/23/2015)... Jan. 23, 2015  Northwest Biotherapeutics, Inc. (NASDAQ: NWBO ... therapies for operable and inoperable solid tumor cancers, announced today ... 7 th Annual Phacilitate Immunotherapy Forum in ... Phacilitate will take place on January 26 at 10:30 a.m. ...
(Date:1/23/2015)... , Jan. 23, 2015 /PRNewswire/-- Harwood Feffer LLP ( ... of directors of Advaxis, Inc. ("Advaxis" or the "Company") ... has breached its fiduciary duties to shareholders. ... an investing website reporting that Advaxis had misrepresented the ...
Breaking Medicine Technology:No One-Size-Fits-All Remedy for Hernia Correction 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3Harwood Feffer LLP Announces Investigation of Advaxis, Inc. 2
Cached News: