Diabetes targets will be impractical in routin...( Targets due to be set as part of the na...)

Diabetes targets will be impractical in routine practice

Targets due to be set as part of the national service framework for diabetes in England and Wales will be impractical for use in routine clinical care, according to an article in this week's BMJ.

Aggressive treatment of high levels of blood sugar, cholesterol, and blood pressure and regular use of antiplatelet drugs has been advocated in type 2 diabetes. Yet current targets are attainable in only 50-70% of individuals in research studies, argues Peter Winocour of Queen Elizabeth II Hospital in Hertfordshire.

The targets are often impractical and involve taking too many drugs, with which patients often will not comply, he adds. Individually tailored targets would be preferable, taking account of factors such as estimated duration of diabetes, obesity, age and lifestyle.

Given the cardiovascular risk profile of type 2 diabetes, up to 10% of patients could require as many as nine drugs. A high proportion will also require treatment for existing heart disease and coincidental unrelated chronic disease, says the author. "It is difficult to see how we can realistically expect patients to comply for long with such a draconian regimen requiring so many separate drugs."

He concludes: "The development of combination tablets by the pharmaceutical industry seems of the utmost priority for effective prevention of complications of type 2 diabetes. Until then we must be pragmatic. We should set targets that are reasonable for our clinics and our individual patients."

'"/>

Contact: Emma Wilkinson
ewilkinson@bmj.com
44-207-383-6529
BMJ-British Medical Journal
27-Jun-2002

Post Your Comments:

(Date:11/25/2009)...EACH,Calif.,Nov.25/PRNewswire/--Thanksgivingmealsw...inthegreaterLongBeachareathankstoFaithInAction/Vol...eatHome(IAH),adivisionofSCANHealthPlan.Formorethan...unteerstodeliverwarmThanksgivingmealstoseniorsinne...sAngelesandsurroundingcities. ,, "Ourwarmholida...

(Date:11/25/2009)...dPoliticalEndorsements,Business,andPressJoinEffort...SNewswire/--Onceagain,theNationalBipolarFoundation...rsingtheir"Safe,tilStable"program,whichisnowbeingw...lardisorder.Today,theNationalBipolarFoundationrece...orityMailfromtheLt.GovernorofLouisianaMitchLandrie...

(Date:11/25/2009)... increase blood pressure? This simple question ha...s. New Stress-related gene Modulates High Blood P... pressure? This simple question has been the focu...earch has for the first time established a link be...ure response to stress in mice as well as humans. ...

(Date:11/25/2009)...etfulness could lead mothers to overlook needed ca...HealthDay News) -- A mother,s depression can worse... , Their six-month study of 262 black mothers a...s had more depressive symptoms had more frequent a...er depressive symptoms had less frequent asthma sy...

(Date:11/25/2009)...GTON,Va.,Nov.25/PRNewswire-USNewswire/--TheAmerica...hCareFraudActof2009,"S.2128,whichisdesignedtosubst...fraudinMedicare.ThebillwasintroducedbySen.GeorgeLe...provisionstheAmericanAssociationforHomecareoutline...tionproposedtoCongressinFebruary.Thoseprovisionsin...

Breaking Medicine News(10 mins):Health News:SCAN Employees and Community Volunteers to Help Deliver One Thousand Thanksgiving Meals to Homebound Seniors 2 Health News:First Time-Door is Open for Family Discussion of Bipolar Disorder 2 Health News:First Time-Door is Open for Family Discussion of Bipolar Disorder 3 Health News:New stress-related gene modulates high blood pressure in mice and men 2 Health News:Mom's Depression May Worsen Child's Asthma 2 Health News:American Association for Homecare Endorses New U.S. Senate Bill, the 'Prevent Health Care Fraud Act of 2009' 2

[0] SCAN Employees and Community Volunteers to Help Deliver One Thousand Thanksgiving Meals to Homebound Seniors [0] First Time-Door is Open for Family Discussion of Bipolar Disorder [0] New stress-related gene modulates high blood pressure in mice and men [0] Mom's Depression May Worsen Child's Asthma [1] American Association for Homecare Endorses New U.S. Senate Bill, the 'Prevent Health Care Fraud Act of 2009'

(Date:11/25/2009)...AINVIEW,Calif.,Nov.25/PRNewswire/-- ChemoCentryx,...theCompany,sPROTECT-1(theProspectiveRandomizedOral...EN(TM)(CCX282-B)inpatientswithmoderate-to-severeCr...ablesafetyandtolerabilityprofile.Thestudydemonstra...seseverityasdefinedasa70-pointdecreaseintheCrohn,s...

(Date:11/24/2009)...ON,N.J.,Nov.24/PRNewswire-FirstCall/--QuestDiagnos...iderofdiagnostictesting,informationandservices,ann...JaffrayHealthcareConferenceinNewYorkCity.Thepresen...a.m.EasternTime. ,, Duringtheconference,thecomp...proximate3%,operatingincometoexceed18%ofrevenues,a...

(Date:11/24/2009)...AC,Md.,Nov.24/PRNewswire/--Inadditiontofamily,frie...iladelphiajurorstoherThanksgivinggratitudelist. ,...ankfultothem,"shesaidofMonday,sverdictstotaling$10..., Wisneskiisamong12,000womennationwidewhohavesuedW...rapydrugsPremarinandPrempro.Wisneskiandtheothervic...

Breaking Medicine Technology:ChemoCentryx Reports Positive PROTECT-1 Study Results for Traficet-EN(TM) at the GASTRO 2009 UEGW/WCOG Conference 2 ChemoCentryx Reports Positive PROTECT-1 Study Results for Traficet-EN(TM) at the GASTRO 2009 UEGW/WCOG Conference 3 ChemoCentryx Reports Positive PROTECT-1 Study Results for Traficet-EN(TM) at the GASTRO 2009 UEGW/WCOG Conference 4 ChemoCentryx Reports Positive PROTECT-1 Study Results for Traficet-EN(TM) at the GASTRO 2009 UEGW/WCOG Conference 5 Quest Diagnostics To Speak At The 21st Annual Piper Jaffray Healthcare Conference 2 Maryland Woman Thankful for Wyeth Verdicts 2 Campaign Mourns the Death of Senator Edward M Kennedy 55416 1 Campaign Mourns the Death of Senator Edward M Kennedy 55416 2 Roper Industries Announces Proposed Public Offering of Senior Unsecured Notes due 2019 55412 1 Roper Industries Announces Proposed Public Offering of Senior Unsecured Notes due 2019 55412 2 Roper Industries Announces Proposed Public Offering of Senior Unsecured Notes due 2019 55412 3 AAHSA Statement on the Passing of Sen Edward Kennedy 55408 1

[0] ChemoCentryx Reports Positive PROTECT-1 Study Results for Traficet-EN(TM) at the GASTRO 2009 UEGW/WCOG Conference [0] Quest Diagnostics To Speak At The 21st Annual Piper Jaffray Healthcare Conference [0] Maryland Woman Thankful for Wyeth Verdicts

Other News:

...cular intravenous vitamin D formulation have a sig...n older and more commonly used form of vitamin D, ...3, edition of the New England Journal of Medicine....ysician, the three-year study found that patients ...

...rybody sweats. But for people with hyperhidrosis-e...er stops.......A new study by Saint Louis Universi...llion Americans are living with this condition, wh...ation and a reduced quality of life.......The resu...

...o findings published in the Aug. 1 issue of the Jo...litaxel in combination with full doses of carbopla...results appear promising. The study, led by Chandr...ty of Pittsburgh and co-director, Lung Cancer Prog...

...some of the problems that biomedical scientists fa...rch is changing from small-scale investigator-led ...as the Human Genome Project. Discussing a recent b...mments that scientific training will have to move ...

health news:Newer vitamin D formulation appears to help dialysis patients live longer 2 health news:Newer vitamin D formulation appears to help dialysis patients live longer 3 health news:'Don't sweat it.' It's easier said than done for millions of Americans, Saint Louis U. study shows 2 health news:'Don't sweat it.' It's easier said than done for millions of Americans, Saint Louis U. study shows 3 health news:Study compares three weekly regimens of chemotherapy for lung cancer 2

Newer vitamin D formulation appears to help dialysis patients live longer 'Don't sweat it.' It's easier said than done for millions of Americans, Saint Louis U. study shows Study compares three weekly regimens of chemotherapy for lung cancer Is science stuck in the middle ages?

...experts are alarmed that the government of The Gam...p taking antiretroviral medications in order to tr...ciation (HIVMA) calls on President Yahya Jammeh to...es" AIDS. ... Earlier this year, President Jammeh ...

...nn Teens who have chronic daily headache, especia...risk for suicide than teens who don't have migrain...007, issue of Neurology, the scientific journal of...raine are also more likely to have other psychiatr...

...chios may reduce your body's response to the stres...udy.... "A ten-year follow-up study of young men s...ponses to stress in the lab, were more likely to c...la G. West, associate professor of biobehavioral h...

...g about swallowing makes it harder to do.... Head ...ry or even a tracheostomy tube and mechanical vent...ble.... Dysphagia, or swallowing problems, can als...e strength.... "We swallow a thousand times or mor...

health news:HIVMA opposes The Gambia's unproven AIDS remedy 2 health news:Teens with migraine at greater risk of suicide 2 health news:Pistachios may calm acute stress reaction 2 health news:Exercise science principles strengthen swallowing rehabilitation 2 health news:Exercise science principles strengthen swallowing rehabilitation 3

HIVMA opposes The Gambia's unproven AIDS remedy Teens with migraine at greater risk of suicide Pistachios may calm acute stress reaction Exercise science principles strengthen swallowing rehabilitation

Diabetes targets will be impractical in routin...( Targets due to be set as part of the na...),Health