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Disagreements Between Clinical Trial Oversight Committees And Physicians Can Affect Drug Trial Results

omes of these trials are important to the companies whose drugs are being tested, they have no influence once the trial begins.

"The companies, of course, have input in the overall design of the actual trial, but once it begins, CECs are completely independent. As a matter of policy, CEC members are blinded to the treatment assigned to each patient."

The study was supported by the Duke Clinical Research Institute. Joining Mahaffey in the study were, from Duke, Dr. Barbara Tardiff, Dr. Christopher Granger, Dr. Kerry Lee, Dr. Robert Harrington and Dr. Robert Califf. Dr. Eric Topol, from the Cleveland Clinic, also participated.


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Contact: Richard Merritt
Merri006@mc.duke.edu
919-684-4148
Duke University Medical Center
31-Mar-1998


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