HOME >> MEDICINE >> NEWS
Dispute over toxic shock syndrome

A TAMPON maker says it may try to develop a test for genetic susceptibility to toxic shock syndrome, based on the results of a study announced last week. But critics dispute the study's conclusions, and warn that the work might be used to help companies fight lawsuits from women who contract the illness after using tampons.

Each year in the US alone, several thousand women develop menstrual toxic shock. The symptoms include fever, vomiting and, in 5 per cent of cases, lethal organ failure. The illness is caused by build-up of the toxin TSST-1. It is made by Staphylococcus aureus bacteria, which usually live harmlessly in the anaerobic conditions of the vagina but ramp up production of the toxin when exposed to the air trapped in tampons.

But why do so few of the estimated 50 million women in the US using tampons get ill? Almost certainly because only a few are genetically susceptible, claims a team at the University of Tennessee in Memphis funded by Procter & Gamble, the maker of Tampax.

Last week the researchers told a meeting in Chicago organised by the American Society for Microbiology that blood and vaginal swabs taken from 19 women with menstrual toxic shock lacked the antibodies capable of blocking TSST-1,and only two of the patients developed antibodies while they were recovering.

However, 35 of 39 healthy women did have high levels of effective antibodies. Philip Tierno, the microbiologist at New York University who first uncovered the link between tampons and toxic shock syndrome, disputes the team's claims. "The reason most patients do not develop antibodies is because the toxin prevents antibody formation," he says.

TSST-1 is a superantigen, meaning that high levels can trigger an immune overreaction, preventing antibody production. But the P&G team thinks the lack of antibodies could be linked to a deficit of a protein called complement in the patients' blood.

Complement is made by a gene on chr
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-207-331-2751
New Scientist
24-Sep-2003


Page: 1 2

Related medicine news :

1. Hepatotoxicity and statins
2. Investigational transplant drug effectively preserves kidneys while avoiding toxic side effects
3. UCLA brain scientists crack mystery of how alcohol causes intoxication
4. New therapeutic vaccine for HIV/AIDS eliminates needles and excessive toxicity
5. Patients with cancer detected on screening mammography undergo less toxic treatment
6. Potentially fatal toxicities occur with off-label use of cancer drugs
7. Some herbal medicine products contain potentially toxic amounts of heavy metals
8. FDA buys technology that identifies drug toxicity to heart
9. Licensed alcohol establishments continue to sell to intoxicated patrons
10. Laser method identifies, counts toxic molecules
11. Study on toxic exposures in urban environments

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... AURORA, Colo. (PRWEB) , ... August 31, 2020 ... ... premier provider of innovative higher-learning opportunities through high-quality, career-relevant, and affordable online education ... Emergency Responder Psychology . , Among the first of its kind in ...
(Date:8/31/2020)... ... ... Cure for Covid-19 “PTS” with Mediation & Hypnosis , At this very turbulent time ... experiencing deep anxiety, immense stress, and right now are needing serious relief from a constant ... the planet are experiencing a great degree of emotional discomfort, be it fear or worrying ...
(Date:8/31/2020)... ... 31, 2020 , ... Bonde Innovations, LLC, a venture-backed developer ... failure, today announced that the company has been awarded a Phase 1 Small ... Heart, Lung, and Blood Institute of the National Institutes of Health (NIH). The ...
(Date:8/28/2020)... ... 2020 , ... WHAT , Hespiro™ is a new type ... including COVID-19, while reducing the need for scarce mechanical ventilators. It not only ... scrubs it free of carbon dioxide in a completely closed “rebreather” system, important ...
(Date:8/28/2020)... ... August 28, 2020 , ... Integrated Viral Protection ... the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air Protection System ... True North Classical Academy plans to fully reopen equipped with the filtration system on ...
Breaking Medicine News(10 mins):
(Date:8/26/2020)... ... August 26, 2020 , ... ScripHessco has announced the ... infographic breaks down ways that chiropractors can help heal sports injuries and get ... “Athletes have an unusual amount of pressure and stress on their bodies, so ...
(Date:8/26/2020)... ... August 26, 2020 , ... ... today announced that it has entered into definitive agreement to acquire ProCE, ... focused on pharmacists and pharmacy technicians. , CEA represents a growing ...
(Date:8/26/2020)... ... 2020 , ... The Lymphoma Research Foundation (LRF) ... serving the lymphoma community through education programs, outreach initiatives and patient services – ... Charity Auction on Wednesday, Sept. 30 . The “Finding Cures Starts With ...
Breaking Medicine Technology:
Cached News: