Do cigarette additives pose additional risk to smokers?

(December 27, 2004) Bethesda, MD The U.S. government does not approve or control the "599 list" of non-tobacco chemical ingredients used to manufacture cigarettes. These additives, such as acetic acid (vinegar), chocolate, vanilla, and menthol are found in everyday foods. Scientists, supported by the U.S. Food and Drug Administration (FDA), generally regard these substances as safe in foods, but the risks for smokers are not known after combustion in cigarettes and inhalation. Can the toxicological effects for smokers be measured? A new report concludes they can.

The Study

The independent, non-profit organization Life Sciences Research Office (LSRO) (WWW.LSRO.ORG) is conducting a review of how to determine the potential risk of non-tobacco additives for cigarette smokers. In a previous report LSRO concluded that testing added ingredients was feasible. In this latest published report, Evaluation of Cigarette Ingredients: Scientific Criteria, LSRO establishes scientific criteria for assessing the impact.

The criteria are based on the work of an expert panel, composed of Alwynelle S. Ahl, Ph.D., D.V.M., Highland Rim Consultancy, Lyles, TN; Carroll Cross, M.D., Professor, Department of Medicine, University of California Davis Medical Center, Sacramento, CA; Shayne Gad, Ph.D., D.A.B.T., President, Gad Consulting Services, Cary, NC; Donald Gardner, Ph.D., F.A.T.S., President, Inhalation Toxicology Associates, Raleigh, NC; Louis Homer, M.D., Ph.D., Medical Director (ret.), Legacy Research Foundation, Portland, OR; Rudolph Jaeger, Ph.D., Principal Scientist, Environmental Medicine, Inc., Westwood, NJ; Robert Orth, Ph.D., President, Apis Discoveries, LLC, Cedar Hill, MO; Emmanuel Rubin, M.D., Chair, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA; James Schardein, M.S., F.A.T.S., Consultant, Leesburg, FL; and Thomas Slaga, Ph.D., President, AMC Cancer Resea


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