HOME >> MEDICINE >> NEWS
Dopamine may play role in cue-induced craving distinct from its role regulating reward effects

NIDA-supported researchers from Brookhaven National Laboratory and the State University of New York at Stony Brook have found evidence in humans that dopamine plays a role in the conditioned cue response to food. Cuesseeing, smelling, and tasting something enjoyableincrease the desire for the reward without necessarily enhancing the pleasure of the reward itself.

Positron emission tomography (PET) was used to measure changes in dopamine in the brains of 10 healthy adults (eight men and two women) during food and neutral stimulations. Food stimulation consisted of the participants viewing, smelling, and tasting their favorite foods but not actually eating the foods. For neutral stimulation, participants described their family genealogy in detail. Prior to and during food stimulation, participants were instructed to rate their feelings of "hunger," "desire for food," "alertness," "stimulation," and "talkativeness" on a scale of 1 to 10. Participants had fasted 16-20 hours before PET scans were conducted.

Food stimulation caused an increase in dopamine in the dorsal striatum but not in the ventral striatum, where the nucleus accumbens is located. This suggests that dopamine may be involved in food motivation that is distinct from its role in regulating food's reward effects through the nucleus accumbens. Previous research has linked increases in dopamine in the nucleus accumbens, the reward center of the brain, with addiction.

WHAT IT MEANS: The finding that dopamine may play a role in cue-induced effects could have important implications in drug addiction research. Many individuals addicted to drugs, especially cocaine and nicotine, are susceptible to cue-induced cravings. A better understanding of the biological basis of cue-related behaviors may provide better insights in the development of more effective behavioral and pharmacological treatments for drug addiction.


'"/>

Contact: Blair Gately
bgately@nida.nih.gov
301-443-6245
NIH/National Institute on Drug Abuse
28-May-2002


Page: 1

Related medicine news :

1. Dopamine key to learning likes and dislikes, says Colorado U. team
2. Its a gamble: Dopamine levels tied to uncertainty of rewards
3. New Findings On Dopamine Receptor Biology: Implications For Mental Illness
4. Breakthrough? Study Finds Dopamine Cannot Be Source Of Pleasure In Brain
5. Brain regions activated by food craving overlap with areas implicated in drug craving
6. Single cocaine exposure boosts both drug craving and avoidance
7. Comfort-food cravings may be bodys attempt to put brake on chronic stress
8. Compounds also present in alcoholic beverages may explain chocolate cravings
9. Drug that curbs nicotine craving may do same for cocaine
10. Patients recovering from depression with talk therapy show a distinct pattern of brain changes
11. Late-onset schizophrenia found to be distinct condition

Post Your Comments:
(Date:8/28/2015)... ... August 29, 2015 , ... Rio Salado College joined nine educational ... as part of the EDUCAUSE - Next Generation Learning Challenges 2015 Breakthrough Models Incubator ... third Breakthrough Models Incubator hosted by EDUCAUSE and NGLC, which is designed ...
(Date:8/28/2015)... ... , ... An article published August 19th by the LA Times ... to open a pizzeria in Westchester. Mr. LaRocco was aware from opening prior pizza ... the current process, having already gone on for over a year, is taking much ...
(Date:8/28/2015)... ... 28, 2015 , ... The 6th Annual Survivor in the City, Chicago ... yet another accolade to its cadre of widespread support—an official letter of support and ... of the medical community and the University of Illinois at Chicago’s Department of Neurosurgery, ...
(Date:8/28/2015)... ... August 28, 2015 , ... Altima Technologies, ... diagramming network and data center assets and audio-video devices, recently released Visio Stencils ... 5000 Series, HP ProLiant Gen9, EMC VNX Series , Super Micro Computer SuperStorage, ...
(Date:8/28/2015)... ... ... Dr. Gregory K. Toumayan, D.C., Q.M.E., is now treating patients with back pain and ... neck pain, stiffness, muscle spasms, and numbness. , Dr. Toumayan received his Bachelor ... to earn his title of Doctor of Chiropractic from the Palmer College of Chiropractic ...
Breaking Medicine News(10 mins):Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 3Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 4Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 3Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 2Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 3Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 2Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 3
(Date:8/27/2015)... Biosimilars are not generics and the ... and Drug Administration (FDA) for recognizing that each ... guidance issued today. The FDA,s draft guidance on ... calling for biological products to bear a nonproprietary ... reflects the agency,s thinking that "there is a ...
(Date:8/27/2015)... , August 27, 2015 According to ... (Transfer, Hammock, Toilet, Seating, Universal, Standing, Bariatric ), Material (Nylon, Padded, ... Forecast to 2020", published by MarketsandMarkets, the Medical Lifting Sling Market ... 411.5 Million in 2015, at a CAGR of 11.4 % from ... ma rket data T ables and ...
(Date:8/27/2015)... , Aug. 27, 2015  Now that Intuitive ... Da Vinci S™ surgical robot, hospitals with robotic surgery ... They also need to see where they stand with ... the right patients? Have they adopted best practices for ... program in the future? ECRI Institute, which ...
Breaking Medicine Technology:Biologics Prescribers Collaborative (BPC) Statement on FDA Draft Guidance entitled "Nonproprietary Naming of Biological Products" 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 3Medical Lifting Sling Market Worth USD 706.0 Million by 2020 4ECRI Institute's New Robotic Surgery Service Helps Hospitals Brace for Change 2ECRI Institute's New Robotic Surgery Service Helps Hospitals Brace for Change 3
Cached News: