HOME >> MEDICINE >> NEWS
Drug to fight virus in transplant patients moves forward in trials

ANN ARBOR, Mich.---A drug once considered for cancer chemotherapy is advancing in clinical trials to test its effectiveness in fighting a virus from the herpes family that threatens transplant patients.

University of Michigan professors Leroy Townsend and John Drach developed the compound maribavir. It is licensed by ViroPharma, which announced today that maribavir is headed for phase 2 clinical trials for the treatment of cytomegalovirus infection in stem cell transplant patients. New drugs go through three phases of clinical trials before the Food and Drug Administration decides on their approval.

Cytomegalovirus (CMV) is part of the herpes virus family, which also includes the viruses that causes chicken pox, mononucleosis and herpes simplexes 1 and 2. Like other herpes viruses, CMV can remain dormant in the body for long periods of time.

In most people with intact immune systems, CMV causes little to no apparent illness. However, in people with weakened immune systems, CMV can lead to serious complications or death.

Patients who are immunosuppressed following transplant of hematopoietic stem cells, such as a bone marrow transplant or solid organ transplantation, are at high risk of CMV infection, as are AIDS patients, fetuses and newborns. In these patients, CMV can lead to conditions such as pneumonitis or hepatitis, or to complications such as acute or chronic rejection of a transplanted organ. When contracted in utero or at birth, CMV can cause babies to be born with birth defects or impairment such as hearing loss.

ViroPharma Inc. (Nasdaq:VPHM) is looking at the potential effectiveness and safety of the oral antiviral drug for transplant patients in the phase 2 trial. The study will be conducted at up to 15 transplant centers across the United States.

Drach, a biochemist and virologist who is a professor in the schools of dentistry and pharmacy, and Townsend, emeritus professor in chemistry and Pharmacy's med
'"/>

Contact: Colleen Newvine
cnewvine@umich.edu
734-647-4411
University of Michigan
29-Jul-2004


Page: 1 2 3

Related medicine news :

1. Billions in cost estimated for firefighter injuries
2. Chemicals found in cherries may help fight diabetes
3. Harlem Hospital Center, Columbia affiliate, recognized for efforts to fight glaucoma
4. O Christmas tree: Your bark may fight arthritis
5. Antibiotic rifampicin shows promise for fighting Parkinsons disease in lab tests
6. Female condoms overlooked in fight against spread of HIV/AIDS
7. HHS awards $10.4 million to fight AIDS on three continents
8. Compound in apples may help fight Alzheimers disease
9. Research on fabrics and cancer-fighting foods featured at ACS meeting
10. Gene-silencing technique offers new way to fight drug-resistant leukemia
11. Strong-flavored onions show promise for fighting cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... YORK (PRWEB) , ... August 31, 2020 , ... ... nation’s largest non-profit organization devoted exclusively to funding innovative lymphoma research and serving ... patient services – today announced the 10th Anniversary of Blood Cancer Awareness Month ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... 31, 2020 , ... Dr. Chang has over 20 years ... other developmental disabilities, as well as supporting staff in caring for patients and ... consultation, and staff development. She joined the company in 2015 as Chief of ...
(Date:8/28/2020)... ... August 28, 2020 , ... ... to a customized Lighthouse Health & Wellness mobile app and web-portal. NCPCV received ... Motorola Solutions Foundation awards grants each year to organizations, such as Destination Imagination, ...
(Date:8/27/2020)... ... 27, 2020 , ... Walk-in Dermatology’s SK-IN Medical Aesthetics Center ... New York location. , Loren received her New York esthetic license in ... chemical peels, microdermabrasion, Hydrafacial MD, dermaplaning, facial lymphatic, and various laser procedures. Loren ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... ... 2020 , ... Trella Health, the leading source of provider ... CRM, marketing automation, and contact center solutions for senior living communities and post-acute ... performance intelligence data and insights into Enquire’s CRM solution to serve as a ...
(Date:8/26/2020)... ... August 26, 2020 , ... AseptiScope, a privately funded ... Company of the Year by MedTech Outlook. , “AseptiScope is pleased to ... first time, clinicians who wear gloves on their hands, goggles on their eyes, covers ...
(Date:8/26/2020)... ... 2020 , ... As the U.S. struggles in its 6th month of fighting ... Wear a mask, keep your distance, wash your hands. Prevention is the best tool ... in 1977, “How much better it is to prevent disease than to cure it.” ...
Breaking Medicine Technology:
Cached News: