HOME >> MEDICINE >> NEWS
Drug to treat ADHD has similar effect on children with reading disorders

The drug methylphenidate (brand name Ritalin) increased activity in brains of children with attention-deficit/hyperactivity disorder (ADHD) as well as those with a reading disorder, researchers at Yale report in the American Journal of Psychiatry.

"During a test of divided attention, Ritalin increased activation in the basal ganglia, a structure of the brain involved in cognition and behavior," said first author Keith Shafritz, former graduate student in the interdepartmental Neuroscience Program at Yale and now a research associate at Duke University Medical Center. "We saw this activation in children with ADHD and those with reading disorder."

The study used functional magnetic resonance imaging (fMRI) to analyze the effect of the drug on brain function. Researchers found that adolescents with ADHD or reading disorder who were on placebo (not medicated) had less activation of the basal ganglia than a group of healthy participants. When the same participants received Ritalin, the drug normalized the activation, which relates to the amount of blood flow to a specific brain region in response to a cognitive task.

ADHD is characterized by inattention, but previous neuroimaging studies have examined the brain dysfunction associated with impulsivity. "This is one of few studies that used a test for attention rather than a cognitive test for impulsivity," said Shafritz. "It is also the first study, using fMRI to find that the attention circuitry in the brain is directly affected by ADHD."

The 27 study participants, ages 14 to 18 with either ADHD or reading disorder, were randomly assigned to receive Ritalin first or placebo first and didn't know to which group they were assigned. While in the MRI, the participants were given auditory or visual performance tasks to decide whether they saw or heard a real English word or a nonsense word. Their results were compared to a group of 14 healthy adolescents who were not given Rital
'"/>

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
13-Dec-2004


Page: 1 2

Related medicine news :

1. First head-to-head study to compare lidoderm patch and Celebrex in treating pain
2. Hormonal treatment improves survival in high-risk prostate cancer patients
3. Chronic pain treatments more effective when taken together, new study shows
4. Brain activity prior to treatment flags vulnerability to antidepressant side effects
5. Unexpected benefit seen in treating HER-2 breast cancer with new preoperative drug combo
6. OHSU scientists test medication to treat involuntary weight loss
7. Cultural and social factors influence prostate cancer treatment
8. Research offers hope of new treatments for liver damage
9. First mouse model for multiple system atrophy points to new treatment targets for brain diseases
10. Risky surgery not always necessary to treat cervical disease
11. Stanford patient is first to test new treatment for peripheral arterial disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... Milwaukee, WI (PRWEB) , ... October 13, 2017 , ... ... movement in medicine known as “patient engagement.” The patient is doing more than filling ... research partners. , “There is an increasing emphasis in health care and research ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... certification process to promote standards of excellence for the field of eating disorders, ... March 22 – 25, 2018 in Orlando, Florida at the Omni Resort at ...
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & ... and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to ... with elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded ...
(Date:10/13/2017)... ... , ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to ... unique items from across the nation, this holiday-themed event will raise funds and awareness ... VNA. The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 ...
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released a ... books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture of ... have tossed it off as mere rubbish, but Yisrayl Hawkins says that is because ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... Sept. 27, 2017  Commended for their devotion to personalized ... Ranked as number one in the South Florida Business Journal,s ... Inc. 5000 yearly list, the national specialty pharmacy has found ... Bardisa will soon be honored by SFBJ as the ... Set to receive his award in October, Bardisa ...
(Date:9/23/2017)... Sept. 22, 2017 Janssen Biotech, Inc. (Janssen) ... letter from the U.S. Food and Drug Administration (FDA) ... sirukumab for the treatment of moderately to severely active ... clinical data are needed to further evaluate the safety ... active RA. ...
(Date:9/19/2017)... LOUISVILLE, Ky. , Sept. 19, 2017   ZirMed ... and predictive analytics, today announced that it has been ranked ... the Black Book™ Rankings 2017 User Survey. ZirMed ... software solution for large hospitals and medical centers over 200 ... in Black Book,s healthcare technology user survey history. ...
Breaking Medicine Technology:
Cached News: