HOME >> MEDICINE >> NEWS
Duke geneticists unraveling the tangled web of autism

DURHAM, N.C. -- Less than three years after beginning a search for genes that confer a risk of developing autism, Duke geneticist Margaret Pericak-Vance and her colleagues have found evidence of two defects that may be linked to the complex combination of behaviors called autistic spectrum disorder.

Such behaviors include failure to make eye contact, social withdrawal, lack of language, and repetitive behaviors such as rocking or head banging. Doctors believe that the disorder begins during development of the brain, possibly even before birth, and that the change prevents affected people from properly processing sensory information from their environment.

Pericak-Vance, director of the Duke Center for Human Genetics and lead investigator of the autism genetic studies at Duke, and her team located defects in tiny sections of chromosomes 15 and 7. And, for the first time, they said they have evidence of a genetic mechanism that hides the effect of some genes.

"You could say we have it narrowed down to a line-up of good suspects, but we still can't finger the culprit until we get direct evidence," Pericak-Vance said. "In this case, that most likely will be more than one gene. It will probably include variations of many genes that in combination interact to result in autistic behavior. Those details will come with continued research of our suspect genes."

The research was supported by the Duke's Center for Human Genetics, the National Alliance of Autism Research, and by grants from the National Institutes of Health.

The collaborative group of scientists, which included researchers and clinicians from Duke, the University of South Carolina, and Johns Hopkins University, located and collected genetic information on more than 100 families with at least two autistic children. By comparing the genes from parents and siblings to the genes of autistic children, the scientists were able to narrow their search to a few small pieces of chromosomes, the
'"/>

Contact: Renee Twombly
twomb001@mc.duke.edu
919-684-4148
Duke University Medical Center
26-Jan-2000


Page: 1 2 3 4 5 6

Related medicine news :

1. UCLA geneticists find location of major gene in ADHD; targeted region also linked to autism
2. Kin of people with heart disease have tangled clots
3. Helping answer needs by developing specialists in autism
4. Effects of autism reach beyond language, new research suggests
5. Monkey pay-per-view study could aid understanding of autism
6. Mayo Clinic study suggests no link between autism and immunizations
7. Brains of people with autism recall letters of the alphabet in brain areas dealing with shapes
8. Brain inflammation found in autism
9. Brains immune system triggered in autism
10. MRI shows brain changes underlying language deficits in autism
11. Imaging studies clarify brain changes associated with language deficits in autism

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/2/2016)... York, NY (PRWEB) , ... December 02, 2016 ... ... featuring an inspirational interview of two ostomy patients, standing as living proof that ... people suffer from digestive diseases and issues that spike around the holidays. This ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... ... edition of "Cardiovascular Health" in USA Today, which covers the innovative treatments, therapeutic ... health while maintaining fulfilling lives. “We are prolonging life 6 years in the ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... diagnostic imaging systems and the first company to offer robotic imaging to ... at their tradeshow booth # 941 for the American Association of Equine Practitioners ...
(Date:12/2/2016)... ... 2016 , ... Yisrayl Hawkins, at The House of Yahweh in Abilene, Texas, ... Bible Prophecy. Yisrayl says this generation, known as the Last Generation, started in 1934 ... details line up exactly with Bible Prophecy – a protected way for those who ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... needy individuals and families from eight different sites throughout Miami-Dade and Broward counties. ... 1,000 volunteers worked very hard on Thanksgiving morning by putting together individual meals ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... DUBLIN , Dec 1, 2016 ... report "Drug Delivery in Cancer - Technologies, Markets and Companies" ... , ... a challenge in management of cancer The market value ... separate. Cancer market estimates from 2015-2025 are given according to organs ...
(Date:12/2/2016)... , Dec. 1, 2016 Around the ... country, region and each habitable land present over earth. ... every individual once in a life time this is ... care available until now. Given the steady increase in ... together with the spiraling healthcare costs of treatment, there ...
(Date:12/2/2016)... Allergan plc (NYSE: AGN ), a ... previously announced Accelerated Share Repurchase (ASR) Program. Logo - ... ... previously announced, the Company entered into a variable tenor ASR ... repurchase $10 billion of its ordinary shares. Approximately 40.5 million ...
Breaking Medicine Technology:
Cached News: