HOME >> MEDICINE >> NEWS
Early reports of thrombosis after insertion of drug-eluting stents

This release is also available in German.

Authors of a research letter in this week's issue of THE LANCET highlight how the use of drug-eluting stents (DES) may carry a risk of subsequent thrombosis if stenting is accompanied by a withdrawal of antiplatelet therapy.

More than 1.5 million people a year have stents implanted to improve coronary artery blood flow. A recently published pooled analysis of 11 trials (see Lancet 2004; 364: 583-91) suggested that DES--increasingly used in coronary angioplasty--have benefits over bare-metal stents (BMS) by reducing the need for later revascularisation and reducing the risk of cardiac events.

Patrick W Serruys (Erasmus Medical Center, Netherlands) and colleagues report four cases of angiographically-confirmed stent thrombosis that occurred around a year after elective implantation of polymer-based paxlitaxel-eluting or sirolimus-eluting stents; all four cases resulted in myocardial infarction (heart attack). All cases arose soon after antiplatelet therapy was interrupted.

Professor Serruys comments: "We report these cases to draw attention to a problem, with serious clinical implications, that might be under-reported. We suggest that the potential risk of stent occlusion should be considered when discontinuation of antiplatelet therapy is contemplated in patients with drug-eluting stents. As the use of drug-eluting stents becomes widespread, careful long-term follow-up of patients with such stents is needed to assess the true rate of late thrombosis."

In an accompanying commentary (p 1466), Mark J Eisenberg (Jewish General Hospital/McGill University, Montreal, Canada) concludes: "drug-eluting stents are so new that many health-care professionals are not aware of the critical need for prolonged and continuous antiplatelet therapy. Therefore, both patients and physicians should be sensitised to the possibi
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
21-Oct-2004


Page: 1 2

Related medicine news :

1. Early onset of puberty the EU gets serious
2. Early HIV screening prolongs life and is affordable, Stanford study shows
3. Early supported discharge services can reduce long term dependency for stroke patients
4. Early surgical treatment not always necessary for patients with brain haemorrhage
5. Early seizures after epilepsy surgery predict more seizures
6. Early learning leaves lasting changes in brain, Stanford owl study shows
7. Early detection reduces threat of foot injury in college basketball players
8. Early results shed light on lung cancer screening advance
9. Early disclosure: Post-operative radiotherapy improves progression-free survival in prostate cancer
10. Early behavior problems linked with wheezing later in childhood
11. Early childhood ear infections linked to asthma

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... Miss. (PRWEB) , ... August 31, 2020 , ... ... (GCPP) recently donated 1,400 N95 face masks to medical first responders across the ... continued to make donations of personal protective equipment (PPE) medical centers , ...
(Date:8/31/2020)... , ... August 31, 2020 , ... The pandemic and topsy-turvy economic outlook continues to ... budgets and look for ways to trim the fat from our monthly expenses and put ... but it’s also important that you have a financial safety net in place in case ...
(Date:8/29/2020)... ... August 29, 2020 , ... When professor and author Randy Pausch was ... most people would. Rather than become melancholic, however, he put together a final lecture ... dreams. Randy Pausch took a negative situation and turned it into something that inspired ...
(Date:8/28/2020)... ... ... Integrated Viral Protection (IVP Air) today announced that the True North Classical ... Indoor Air Protection System that is the first system designed and proven to catch ... the filtration system on September 8th. , The IVP Air S1 model is ...
(Date:8/27/2020)... MORRISTOWN, N.J. (PRWEB) , ... August 27, 2020 ... ... has continued to partner with Evolution Labs to provide their students with Suite360:Mental ... issues related to Mental Health, Substance Abuse and Child Trafficking Prevention. , Florida ...
Breaking Medicine News(10 mins):
(Date:8/28/2020)... ... 2020 , ... Cano Health, LLC, a leading population health ... Antonio is happy to announce that it has selected Tejano musician Jay Perez ... will serve as community advisor, advertising talent, and creative consultant for Cano Health, ...
(Date:8/27/2020)... (PRWEB) , ... August 27, 2020 , ... Austin Oral ... – is pleased to announce Dr. David Szalay, DDS, MD, has joined the practice. ... patients in the new Pflugerville office, which is scheduled to open this fall. The ...
(Date:8/27/2020)... FORT MYERS, Fla. (PRWEB) , ... August 27, 2020 , ... ... its Board of Directors. Dr. Friedman is an adult and pediatric neuro-oncologist who serves ... Duke University and as an educator at Duke University Medical School. , Internationally recognized, ...
Breaking Medicine Technology:
Cached News: