HOME >> MEDICINE >> NEWS
Effectiveness of drugs used to treat Parkinson's disease in early, later stages measured

DENVER, CO The use of different medications during early versus later stages of Parkinsons disease is critical to managing symptoms and perhaps the progression of the disease, according to a study presented at the Annual Meeting of the American Academy of Neurology.

The main pathologic and biochemical characteristic of Parkinsons disease is the selective cell death of dopaminergic neurons in the midbrain area called substantia nigra and marked decrease in dopamine neurotransmitter produced by these neurons.

In a study conducted by the Parkinson Study Group and led by investigators at the Institute for Neurodegenerative Disorders in New Haven, Conn., the rate of this dopaminergic degeneration after early treatment with the drugs pramipexole and levodopa, administered to 82 early Parkinsons patients, was compared using brain imaging.

Our data suggest that patients initially treated with pramipexole experience a significantly slower rate of loss of dopaminergic neuronal functioning compared to those treated with levodopa, said study author Kenneth Marek, MD. While there remains debate about treatment for early Parkinsons disease -- and all treatment should be individualized to meet the needs of the patient this study adds important new information to the growing body of knowledge on the early treatment of Parkinsons disease.

Ultimately, most patients will be treated with both levodopa and a dopamine agonist, Marek said.

Marek cautions that further, long-term study comparing the clinical endpoints of these drug therapies relative to Parkinsons progression will be required to assess the clinical impact of these imaging findings.


'"/>

Contact: Cheryl Alementi
calementi@aan.com
651-695-2737
American Academy of Neurology
16-Apr-2002


Page: 1

Related medicine news :

1. Effectiveness of safer smallpox vaccine demonstrated against monkeypox
2. Effectiveness of chickenpox vaccine decreases after one year
3. University Of Pittsburgh Cancer Institute Defines First Immunologic Markers Of Interferon Effectiveness Against Melanoma
4. Interleukin-2 Boosts Cancer Vaccine Effectiveness In Mice
5. Discovery May Boost Effectiveness Of Chemotherapy
6. National Clinical Trial To Test Effectiveness Of Antibiotic Treatment For Coronary Artery Disease
7. Changing Drug Delivery For Rheumatoid Arthritis Patients Increases Effectiveness, Lowers Costs
8. Study Pinpoints Effectiveness Of Prostate Cancer Therapies To Patient Populations
9. Four-Year Study Shows Long-Term Effectiveness Of Proscar In Treating Enlarged Prostates
10. Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs
11. Scientists Track Effectiveness Of Migraine Drugs With Ultrasound

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/16/2019)... ... June 14, 2019 , ... ... Security solutions, today announced it has received the coveted “2019 Best DLP Solution ... that Works Platform along with the latest additions to its Data Security Portfolio ...
(Date:6/14/2019)... , ... June 14, 2019 , ... ... Tempur-Pedic® Mattress & Pink Bag Event® scheduled for Saturday, July 13th. UBCF is ... men and children directly impacted by breast cancer. This second event was added ...
(Date:6/13/2019)... ... June 13, 2019 , ... MMJ BioPharma Cultivation, a premier ... memorandum of understanding (MOU) with MMJ International Holdings to grow cannabis and supply ... BioPharma Cultivation will be supplying MMJIH with extracts from the marijuana plant to ...
(Date:6/13/2019)... ... June 13, 2019 , ... Pure Ratios, the ... cannabis delivery company, Driven Deliveries, Inc., the only publicly traded cannabis delivery service ... the population of California with overnight cannabis delivery to major thriving markets such ...
(Date:6/13/2019)... ... June 13, 2019 , ... ... everyone in healthcare, today announced that Jon Elwell, the company’s CEO, has been ... DirectTrust is a non-profit health care industry alliance created to support ...
Breaking Medicine News(10 mins):
(Date:6/13/2019)... ... June 13, 2019 , ... Homecare Homebase ... the new Smart Scheduling product, part of the HCHB Intelligence Suite, at the ... uses complex algorithms to create highly efficient routing, mapping and scheduling for home ...
(Date:6/13/2019)... ... 13, 2019 , ... Access Healthcare , a leading provider of healthcare ... at the HFMA Annual Conference 2019 which will be held on June ... Access Healthcare, says, “HFMA Annual Conference has inspired us in many ways – right ...
(Date:6/13/2019)... ... , ... RxNT announced today that it has been named by ... RxNT is a leader in healthcare technology solutions. This is the fourth time RxNT ... highlight the best software products from North American small businesses. RxNT won the FrontRunner ...
Breaking Medicine Technology:
Cached News: