HOME >> MEDICINE >> NEWS
Effectiveness of drugs used to treat Parkinson's disease in early, later stages measured

DENVER, CO The use of different medications during early versus later stages of Parkinsons disease is critical to managing symptoms and perhaps the progression of the disease, according to a study presented at the Annual Meeting of the American Academy of Neurology.

The main pathologic and biochemical characteristic of Parkinsons disease is the selective cell death of dopaminergic neurons in the midbrain area called substantia nigra and marked decrease in dopamine neurotransmitter produced by these neurons.

In a study conducted by the Parkinson Study Group and led by investigators at the Institute for Neurodegenerative Disorders in New Haven, Conn., the rate of this dopaminergic degeneration after early treatment with the drugs pramipexole and levodopa, administered to 82 early Parkinsons patients, was compared using brain imaging.

Our data suggest that patients initially treated with pramipexole experience a significantly slower rate of loss of dopaminergic neuronal functioning compared to those treated with levodopa, said study author Kenneth Marek, MD. While there remains debate about treatment for early Parkinsons disease -- and all treatment should be individualized to meet the needs of the patient this study adds important new information to the growing body of knowledge on the early treatment of Parkinsons disease.

Ultimately, most patients will be treated with both levodopa and a dopamine agonist, Marek said.

Marek cautions that further, long-term study comparing the clinical endpoints of these drug therapies relative to Parkinsons progression will be required to assess the clinical impact of these imaging findings.


'"/>

Contact: Cheryl Alementi
calementi@aan.com
651-695-2737
American Academy of Neurology
16-Apr-2002


Page: 1

Related medicine news :

1. Effectiveness of safer smallpox vaccine demonstrated against monkeypox
2. Effectiveness of chickenpox vaccine decreases after one year
3. University Of Pittsburgh Cancer Institute Defines First Immunologic Markers Of Interferon Effectiveness Against Melanoma
4. Interleukin-2 Boosts Cancer Vaccine Effectiveness In Mice
5. Discovery May Boost Effectiveness Of Chemotherapy
6. National Clinical Trial To Test Effectiveness Of Antibiotic Treatment For Coronary Artery Disease
7. Changing Drug Delivery For Rheumatoid Arthritis Patients Increases Effectiveness, Lowers Costs
8. Study Pinpoints Effectiveness Of Prostate Cancer Therapies To Patient Populations
9. Four-Year Study Shows Long-Term Effectiveness Of Proscar In Treating Enlarged Prostates
10. Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs
11. Scientists Track Effectiveness Of Migraine Drugs With Ultrasound

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/16/2017)... Angeles, California (PRWEB) , ... August 16, 2017 , ... An August 3rd article ... that was the subject of a report in JAMA (the Journal of the American Medical ... above 50 were able to achieve BMIs under 30, when compared to patients with lower ...
(Date:8/16/2017)... FL (PRWEB) , ... August 16, 2017 , ... ... standardized product data and images announced today that it was acquired by Advantage ... Industry’s solution for product information. IX-ONE’s members include the industry’s leading suppliers, brokers, ...
(Date:8/16/2017)... ... August 16, 2017 , ... In 1987, ... celebrate 30 years in business this year, and they’re marking the milestone by ... to serve their patients. , It stands to reason that, given the ...
(Date:8/16/2017)... ... August 16, 2017 , ... Modern Consulting Insurance & ... program. Partnering once again with Boys & Girls Clubs of Greater Kansas City, ... area’s very own American Idol. With all proceeds benefitting local worthy causes, donations ...
(Date:8/16/2017)... ... August 16, 2017 , ... Paul Vitenas, MD, FACS ... 2017 Top Doctor. The annual list identifies the nation’s top physicians, in a variety ... made it to the top of Castle Connolly’s coveted ranking. , Castle Connolly is ...
Breaking Medicine News(10 mins):
(Date:8/14/2017)... HACKENSACK, N.J. and PETACH TIKVAH, ... Therapeutics Inc. (NASDAQ: BCLI), a leading developer of adult ... for the second quarter ending June 30, 2017. ... advanced stages of preparing for our pivotal Phase 3 ... Chaim Lebovits , President and Chief Executive Officer ...
(Date:8/7/2017)... Md. , Aug. 7, 2017 ... healthcare member acquisition, retention, and engagement, announced the ... of Strategy and Product Development, effective as of ... consulting and technology implementation strategy for our clients. ... of experience in consulting and business analytics within ...
(Date:8/4/2017)... -- The search for test results that can be ... long been the goal of healthcare providers and the ... largest meeting of lab professionals and IVD firms this ... Kalorama Information.  The firm said scores of companies with ... and software were at the American Association for Clinical ...
Breaking Medicine Technology:
Cached News: