HOME >> MEDICINE >> NEWS
Effectiveness of safer smallpox vaccine demonstrated against monkeypox

A mild, experimental smallpox vaccine known as modified vaccinia Ankara (MVA) is nearly as effective as the standard smallpox vaccine in protecting monkeys against monkeypox, a study by researchers of the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health, has found. Monkeypox is used to test the effectiveness of a smallpox vaccine because of its similarity to the smallpox virus. The study appears in the March 11 issue of Nature.

"These findings are important to the search for a replacement vaccine for people with health conditions that would prevent them from using the current smallpox vaccine," says Anthony S. Fauci, M.D., director of NIAID. Currently, Dryvax is the only commercially available smallpox vaccine in the United States. "In addition, because an initial MVA injection may help lessen the side effects experienced from Dryvax, MVA may serve as an important pre-vaccine for large-scale vaccination efforts in the event of a bioterror threat involving smallpox."

NIAID's Bernard Moss, M.D., Ph.D., the senior author on the paper, adds, "This study shows that the MVA vaccine holds great promise as an alternative to the current vaccine. Although MVA may not quite equal Dryvax in its effectiveness, it did extraordinarily well, with all of the monkeys who were vaccinated with MVA surviving a potentially lethal monkeypox infection and, aside from a few minor lesions, showing no clinical signs of disease."

In a separate study published in the March 11 online early edition of the Proceedings of the National Academy of Sciences, Dr. Moss and colleagues found that, in addition to protecting healthy mice against a lethal form of the vaccinia virus, MVA protects mice with certain immune deficiencies as well. The researchers found that mice survived a deadly dose of vaccinia virus if they'd been immunized with MVA--even those mice that were lacking antibody-producing immune cells or s
'"/>

Contact: Jennifer Wenger
jwenger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
10-Mar-2004


Page: 1 2 3 4

Related medicine news :

1. Effectiveness of chickenpox vaccine decreases after one year
2. Effectiveness of drugs used to treat Parkinsons disease in early, later stages measured
3. University Of Pittsburgh Cancer Institute Defines First Immunologic Markers Of Interferon Effectiveness Against Melanoma
4. Interleukin-2 Boosts Cancer Vaccine Effectiveness In Mice
5. Discovery May Boost Effectiveness Of Chemotherapy
6. National Clinical Trial To Test Effectiveness Of Antibiotic Treatment For Coronary Artery Disease
7. Changing Drug Delivery For Rheumatoid Arthritis Patients Increases Effectiveness, Lowers Costs
8. Study Pinpoints Effectiveness Of Prostate Cancer Therapies To Patient Populations
9. Four-Year Study Shows Long-Term Effectiveness Of Proscar In Treating Enlarged Prostates
10. Researchers Finding May Boost Effectiveness Of Anti-HIV Drugs
11. Scientists Track Effectiveness Of Migraine Drugs With Ultrasound

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/2/2019)... (PRWEB) , ... December 02, 2019 , ... ... unsurpassed efficiency and flexibility to the Sterile Processing Department. The elegant design provides ... clean. The P1000 has downward sliding doors that allow for manual loading that ...
(Date:11/30/2019)... ... November 29, 2019 , ... As ... customs, teachers aren’t focusing on the potential for academic backslide but rather opportunities ... their textbooks or logging into GoogleClassroom as often during the break but might ...
(Date:11/27/2019)... , ... November 27, 2019 , ... ... environment—targeting the human sense of smell has a far deeper reach. Aroma travels ... essence can have hugely beneficial effects on both consumers and workers. The human ...
(Date:11/23/2019)... ... November 22, 2019 , ... Congress took ... improve the quality and safety of medical diagnoses. Bipartisan legislation, Improving Diagnosis in ... Luján (D-NM) and Rep. Gus Bilirakis (R-FL) on November 13. , The legislation ...
(Date:11/23/2019)... ... ... The potential of the human brain seems limitless. We have the ability ... In a world of instant messaging and people who intentionally film themselves doing painfully ... it not? But even thinking can be taken too far. Extreme rumination is the ...
Breaking Medicine News(10 mins):
(Date:12/2/2019)... Va. (PRWEB) , ... December 02, 2019 , ... ... make all communities healthier places to live, work, learn, and play. Striving to ... for review against the rigorous national standards set by the Public Health Accreditation ...
(Date:11/30/2019)... ... 29, 2019 , ... In the United States, we regard chefs as a ... there is no shortage of phenomenal restaurants for guests to visit. Meet the chef ... world. Christian Bowman, Chef to NBA All-Stars and celebrities, is a culinary master with ...
(Date:11/27/2019)... ... November 28, 2019 , ... Since the one year anniversary ... Vietnam, the country is ready to roll out the program more widely due to ... Review Forum today, the Vietnam Administration for HIV/AIDS Control (VAAC) presented a review of ...
Breaking Medicine Technology:
Cached News: