HOME >> MEDICINE >> NEWS
Engineered blood vessels prove durable and clot resistant

CHICAGO, Nov. 17 Researchers have built mechanically sound blood vessels out of tissue from human skin cells, according to a study reported today at the American Heart Association's Scientific Sessions 2002. The technique involves tissue engineering, an emerging science that takes cells from the body, manipulates them in the laboratory to create functional tissue, and puts the new tissue back into the patient.

The goal is to produce healthy, functioning blood vessels built exclusively from a person's own cells, so the body's immune system won't reject the new tissue. Such vessels would be important in heart and leg bypass operations and for vessels called arteriovenous shunts used for dialysis patients.

The scientists reported that tissue-engineered blood vessels didn't burst or develop blood clots in laboratory tests and short-term animal experiments.

"The study's most important findings were: First, the technology works from a commercial perspective, meaning we can build mechanically sound vessels for a wide array of patients using the exact same protocol," says Todd McAllister, Ph.D., president and chief executive officer of Cytograft Tissue Engineering in Novato, Calif., which developed the vessel-building technique.

"Second, we demonstrated that thrombogenesis (the formation of blood clots) does not appear to be a problem in the short term up to 14 days. Short-term blood clots are the biggest challenge facing most synthetic materials, whether they are used for blood vessels, new heart valves, or other vascular prostheses. We expect to begin this research in humans within 18 months."

In the study reported today, researchers took fibroblast cells from 11 patients (ages 54 to 84) with advanced cardiovascular disease who had coronary artery bypass operations at Stanford University. Fibroblasts form the outer wall of blood vessels. The researchers used endothelial cells from animals to make the inner lining of the vessels.

Typ
'"/>

Contact: Carole Bullock
carole.bullock@heart.org
214-706-1279
American Heart Association
17-Nov-2002


Page: 1 2 3

Related medicine news :

1. Engineered stem cells can home in on tumors and deliver drug payload in mice
2. BioNumerik Reports Data On Two Novel Supercomputer Engineered Anticancer Agents At 90th Annual Meeting Of The AACR
3. BioNumerik Reports Preclinical Antitumor Data On Two Novel Supercomputer Engineered Anticancer Agents At 89th Annual AACR Conference
4. A marker for new blood vessel formation in tumors
5. Acupuncture found to lower elevations in blood pressure
6. Diagnostic test for range of blood disorders on the horizon
7. Research suggests possible blood test for multiple sclerosis
8. Epstein-Barr virus protein crucial to its role in blood cancers
9. Simple blood test may help to predict cardiovascular risk in older women
10. Drug that hinders blood vessel growth under study in ovarian cancer
11. Laughter helps blood vessels function better

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... September 03, 2020 , ... ... American Foundation for Suicide Prevention’s (AFSP) annual signature event, Out of the Darkness ... of U.S. cities to raise awareness of suicide prevention. To ensure Associate safety, ...
(Date:9/3/2020)... ... September 03, 2020 , ... MemoryCare.com, a comprehensive ... Best Memory Care Facilities in Louisville, KY. The guide identifies 17 memory care ... According to the Alzheimer’s Association , 5.6 million people age 65 and ...
(Date:9/1/2020)... Calif. (PRWEB) , ... September 01, 2020 , ... ... a new practice in Glendale. While the office will be the ... as breast augmentation, tummy tucks, buttock augmentation (Brazilian butt lift), as well as ...
(Date:9/1/2020)... ... ... As fall and winter swiftly approach and many businesses cut costs to ... time to expand and grow into a full-fledged natural health clinic over the past ... relaunching its brand new website, expanding its services menu and has recruited top-tier healthcare ...
(Date:8/31/2020)... ... 2020 , ... The Lymphoma Research Foundation (LRF) ... and serving the lymphoma community through a comprehensive series of education programs, outreach ... Awareness Month (BCAM) and its international Light it Red for Lymphoma ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... Mara C. ... Laser Surgery at the University of Rochester Medical Center, in Upstate New York. ... in Boston, with clinical faculty from the Harvard and Yale Departments of Dermatology ...
(Date:9/1/2020)... ... ... Breast and ovarian cancers are common diseases that affect many women. ... 7,500 women per year) and 10% of ovarian cancers (about 2,000 women per year) ... detectable in the Women’s Excellence Genetic Testing Program. , Dr. Jonathan Zaidan, MD, FACOG, ...
(Date:8/31/2020)... ... ... you live in New York City you will always pay more for these two things: ... supply and demand, but are plastic surgeons in New York worth the premium prices that ... make the four-hour trip to have expert aesthetic treatments by some of the best doctors ...
Breaking Medicine Technology:
Cached News: