HOME >> MEDICINE >> NEWS
Enoxaparin prevents stillbirth in pregnant women with clotting disorder

(WASHINGTON, April 30, 2004) Enoxaparin, an anticoagulant, has proven to be an effective preventive measure against stillbirth in pregnant women with hereditary thrombophilia, according to a new study published in the May 15, 2004, issue of Blood, the official journal of the American Society of Hematology.

Thrombophilia, a tendency for excessive blood clotting, increases the risk of stillbirth because it interrupts the normal circulation of blood from the mother to the placenta. A team of researchers from two French institutions, the University Hospital in Nimes and the University of Montpellier 1, studied 160 pregnant women with genetic risk factors for thrombophilia (heterozygous factor V Leiden mutation, prothrombin G20210A mutation, or protein S deficiency) who had experienced one unexplained stillbirth at 10 weeks gestation or later prior to the study.

Treatment for the women began in their eighth week of the new pregnancy. Eighty participants were provided with 40 mg of enoxaparin by subcutaneous injection each day. Because of ethical concerns regarding providing pregnant women with a placebo, the researchers instead provided the other 80 participants with low-dose aspirin (100 mg daily), a commonly used blood thinner. All participants were also given 5 mg of folic acid a day as an additional preventive measure, beginning at least one month prior to conception and continuing throughout the pregnancy.

The results of enoxaparin use were impressive. Of the women on the drug, 86 percent had a normal live birth. In addition, no significant side effects were seen in these mothers or their newborns. The group taking aspirin suffered 57 pregnancy losses and only 29 percent of the women taking this medication had a successful birth.

The enoxaparin babies also weighed more than those born to the mothers taking aspirin; only 10 percent of enoxaparin newborns were small for their gestational age, compared with 30 percent of the as
'"/>

Contact: Aislinn Raedy
araedy@hematology.org
202-776-0544
American Society of Hematology
30-Apr-2004


Page: 1 2

Related medicine news :

1. Screening for osteoporosis prevents hip fractures in older adults
2. Understanding how prostaglandin prevents gut injury during radiation therapy
3. Exercise prevents Parkinsons symptoms in lab model mimicking human form of the disease
4. Study finds once-daily Valcyte prevents serious viral infection after kidney transplant
5. Enzyme prevents lung damage in premature infants
6. New drug prevents arrhythmias that cause sudden cardiac death
7. Detecting vitamin B12 deficiency prevents anaemia and memory loss
8. Drug prevents diabetes recurrence after islet cell transplantation
9. Gene targeting prevents memory loss in Alzheimers disease model
10. Combined drug therapy prevents progression of prostate enlargement
11. Clean needles for drug injectors prevents HIV/AIDS

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... ProVest Insurance Group, a ... Miami, and Raleigh regions, is organizing an extended charity drive to benefit the ... chromosome abnormality. , After struggling since birth with several health challenges, T.J. was ...
(Date:10/13/2017)... ... October 13, 2017 , ... As health professionals work to improve their approach ... patient is doing more than filling out a survey; in many cases health professionals ... emphasis in health care and research on the importance of active engagement with patients ...
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family ... next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. ... 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon assuming the ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... PurhealthRX ... CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will ... and providing a CBD form that can be easily incorporated into liquid products, while ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Lori R. Somekh, ... member of ElderCounsel, a national organization of elder law and special needs planning attorneys. ... and rules. It also provides a forum to network with elder law attorneys nationwide,” ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... NEW YORK , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: ... data solutions, today announced that its MyDario product is expected to appear ... listings for when The Dr. Oz Show airs in your area: ... The nine-time Emmy award-winning, The ... ...
(Date:9/23/2017)... Sept. 22, 2017 Janssen Biotech, Inc. (Janssen) ... letter from the U.S. Food and Drug Administration (FDA) ... sirukumab for the treatment of moderately to severely active ... clinical data are needed to further evaluate the safety ... active RA. ...
(Date:9/19/2017)... Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy that uses ... today:   ... Jim ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has led R&D and business ...
Breaking Medicine Technology:
Cached News: