HOME >> MEDICINE >> NEWS
European trial finds old lung cancer treatment may still be best

The first clinical trial to compare directly two of the most widely-used drugs in advanced lung cancer, cisplatinin and carboplatin (both in combination with paclitaxel) have concluded that the older drug, cisplatin, is the better treatment.

Patients given cisplatin and paclitaxel had better survival rates and their quality of life was just as good as patients receiving carboplatin and paclitaxel.

The phase III multi-national European trial involving 618 patients with advanced non small-cell lung cancer (NSCLC) is reported in the new issue of Annals of Oncology.*

Cisplatin tends to be the preferred standard chemotherapy for lung cancer in Europe, but in the USA carboplatin is normally used. The new findings are in contrast to a recent similar study in the USA** where a four-arm trial comparing a range of treatments showed no advantage for any one chemotherapy combination over another.

In the European trial the response rates to the two treatments were similar - 28% in the cisplatin/paclitaxel arm and 25% in the carboplatin/paclitaxel arm, but the median survival in the cisplatin arm was significantly better at 9.8 months compared with 8.5 months. The one-year survival rate was 38% in the cisplatin/paclitaxel arm compared with 33% in the carboplatin/paclitaxel arm and the two-year survival rate was 15% and 9% respectively.

Lead investigator Dr Rafael Rosell from the Hospital Germans Trias i Pujol in Barcelona, Spain said: "This large European randomised study can contribute greatly to resolving the longstanding debate on the superiority of carboplatin or cisplatin-based chemotherapy in lung cancer. Although paclitaxel/carboplatin yielded a similar response rate, the significantly longer median survival obtained with paclitaxel/cisplatin indicates that cisplatin-based chemotherapy should be the first treatment option." However, Dr Rosell stressed that paclitaxel/carboplatin was still a viable alternative.

In an acco
'"/>

Contact: Margaret Willson
m.willson@mwcommunications.org.uk
44-153-677-2181
European Society for Medical Oncology
9-Oct-2002


Page: 1 2

Related medicine news :

1. ESC releases the first European Guidelines on Percutaneous Coronary Interventions (PCI)
2. The European Society of Cardiology launches Women at Heart
3. Use of potentially inappropriate medications among elderly common in some European countries
4. European folic acid policies are not effective enough
5. New European cancer figures for 2004 major efforts needed against the big four killers
6. Third of European cancer patients use complementary and alternative therapies
7. A new service from the European Patent Office
8. European study highlights persistent 3 decade increase in childhood cancer incidence
9. European nations urged to ratify international treaty on tobacco control
10. Increased investment in radiotherapy will improve cure rates for European cancer patients
11. ESA looking for more European women to volunteer for WISE bed-rest study in Toulouse next year

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: European trial finds old lung cancer treatment may still best

(Date:3/26/2015)... On March 5, 2015, Portland Trail ... for the season with a torn Achilles tendon in ... Blazers were competing against Dallas, and was confirmed via ... Silva, M.D., who has treated many professional athletes, voiced ... could be prevented. , "Part of the problem ...
(Date:3/26/2015)... NY (PRWEB) March 26, 2015 Volunteers ... raise awareness of Parkinson’s disease and funds to support ... to Ease the Burden – Find the Cure. ... and will take place in more than 20 locations ... Island, New Jersey, San Antonio, Minnesota, Seattle, St. Louis, ...
(Date:3/26/2015)... Hartford, CT (PRWEB) March 26, 2015 ... Connecticut State Capitol Building to help celebrate the achievement ... a groundbreaking employment program serving some 500 people. , ... by The WorkPlace in partnership with the ... coach and prepare long-term unemployed workers and place them ...
(Date:3/26/2015)... Ill. (PRWEB) March 26, 2015 The ... the legacy of a man who revolutionized the business ... posthumously honored Leo Passage; founder of Pivot Point International, ... award on behalf of Leo. Held at the Art ... a “who’s who” of industry and media leaders and ...
(Date:3/26/2015)... 2015 Heroin Abuse in the United ... deaths cause has garnered much attention in recent years. ... increase of heroin abuse and heroin-related overdose deaths. , ... results based on information collected from 28 U.S. states ... U.S. heroin overdose death rates doubled from 2010 through ...
Breaking Medicine News(10 mins):Health News:Sports Medicine Specialist Weighs In on Wesley Matthew’s Significant Tendon Injury; Can it be Prevented? 2Health News:Sports Medicine Specialist Weighs In on Wesley Matthew’s Significant Tendon Injury; Can it be Prevented? 3Health News:Sports Medicine Specialist Weighs In on Wesley Matthew’s Significant Tendon Injury; Can it be Prevented? 4Health News:American Parkinson Disease Association 2015 Optimism Walk Season Launches Nationwide 2Health News:CRN International Shows Support For Groundbreaking Connecticut Program To Aid The Unemployed 2Health News:#BeautyChangesLives Legacy Award Pays Tribute to Industry Icon Leo Passage 2Health News:#BeautyChangesLives Legacy Award Pays Tribute to Industry Icon Leo Passage 3Health News:Narconon Arrowhead Issues Heroin Overdose Prevention Warning 2Health News:Narconon Arrowhead Issues Heroin Overdose Prevention Warning 3
(Date:3/26/2015)... a loved relative suffering from cancer - and you ... too expensive. The Austrian Centre of Industrial Biotechnology (acib) ... costs of highly valued drugs significantly. ... pathogens or cancer cells. Therapeutic antibodies are used as ... diseases such as multiple sclerosis. According to "bccresearch.com" the ...
(Date:3/26/2015)... 26 de marzo de 2015 Finesse ... está diseñado específicamente para innovadores, visionarios y ejecutivos ... dos días, con entrada por invitación únicamente, se ... de San Francisco el ... foro dirigido a líderes en ciencias de la ...
(Date:3/25/2015)... 2015 The majority of foot ailments can be ... is why podiatrists often prescribe orthotics to patients who have ... orthopedic shoes one might find at a store aren,t always ... for a custom orthotic. Learn a bit about the process ... podiatrist Dr. Michael Frank , DPM. Photo ...
Breaking Medicine Technology:World's First Method for Continuous Purification of Valuable Antibodies 2Finesse Solutions presenta Cellworld 2015 2Podiatrist in Silver Spring, Maryland Discusses The Use of Custom Molded Orthotics For Heel Pain 2
Cached News: