HOME >> MEDICINE >> NEWS
Evidence Shows Drug-Psychotherapy Combo Effective For Chronic Depression

WASHINGTON, D.C. -- A new combination of drug treatment and psychotherapy is much more effective than either medication or therapy alone for treating chronic depression, according to preliminary results presented Tuesday, May 18, at the annual meeting of the American Psychiatric Association.

The combination treatment, involving the drug nefazodone and a form of psychotherapy developed specifically to treat chronic depression, also produced the highest response and remission rates for any reported study of chronic depression.

The findings come from the Serzone Chronic Depression Study, the first major study of medication alone, psychotherapy alone, and the combination of both in patients with chronic depression. Nefazodone, prescribed under the brand name Serzone, is used to treat depression and is effective for reducing relapse. The research is funded by Bristol-Myers Squibb Company, makers of Serzone.

Results from the acute phase - the first 12 weeks - of the 80-week study of 681 patients depressed for at least two years shows that a combination of nefazodone and psychotherapy produces an 85 percent response rate. The drug alone leads to a 55 percent rate of response, similar to a 52 percent response rate for psychotherapy.

Nefazodone, alone or in combination therapy, was also associated with improvement in patients much sooner than psychotherapy. The drug also provided significant early and ongoing improvement in insomnia, which is common in chronically depressed patients.

"The extremely large difference in response rates after 12 weeks is truly astonishing," said lead researcher Martin B. Keller, M.D. "This study should put to rest the widespread belief that chronic depression is resistant to drug treatments and psychotherapy." Keller is professor and chairman of the Department of Psychiatry and Human
'"/>

Contact: Scott Turner
Scott_Turner@Brown.edu
401-863-1862
Brown University
18-May-1999


Page: 1 2 3

Related medicine news :

1. Evidence indicates cancer patients unable to intentionally postpone death for significant events
2. Not guilty! Evidence exonerates 328, but many still falsely imprisoned
3. Evidence for shaken baby syndrome is uncertain
4. Evidence suggests that the brain can switch to automatic pilot during learning
5. Evidence that memories are consolidated during sleep
6. Evidence that neurons prune only twigs to rewire themselves
7. Evidence supports two types of heart failure
8. Evidence for warts treatments is weak
9. Evidence does not support psychological treatments for epilepsy
10. Evidence of PSA screening efficacy lacking
11. DDW Studies Present Evidence That Thalomid (Thalidomide) Is Active In Treating Crohns Disease

Post Your Comments:
(Date:4/25/2015)... The URO CENTER of NEW YORK is ... by the New York Academy of Medicine to receive the ... field of Urology. , Dr. Ferdinand Valentine, born in 1851, ... He was a man of rare and attractive personality ... Not only did he devote his life to his profession ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 Bird B Gone, ... residential applications now offers a complete line of bird control ... poultry farms. , New Flu Strains Threaten Pacific, Central and ... USDA post , a number of highly pathogenic avian ... The disease is often spread when wild birds enter poultry ...
(Date:4/24/2015)... Foothill Ranch, California (PRWEB) April 24, 2015 ... that has a wide range of capabilities and services ... etc. , Ryadon's Quantity Discount Program will be ... ) as follows: , Order 4-19: Receive 10% discount ... Can Benefit by Using the Drawer Slides Products, ...
(Date:4/24/2015)... The 1975 have had an ... the globe to theaters, festivals and TV performances. Now that ... with their label, Dirty Hit Records, to provide clean drinking ... newly launched Cadence & Cause website, this four-piece ... vinyl and a signed photo card. Entries from this ...
(Date:4/24/2015)... Carinsurancequotesinfo.com has released a new blog post ... qualify for auto insurance as a single ... insurance online, without having to follow a special process. ... can reduce their auto insurance expenses. The tips are ... , Clients can now visit an insurance brokerage ...
Breaking Medicine News(10 mins):Health News:The 2015 Valentine Award Comes From The Heart and Goes To Famous New York Urologist 2Health News:The 2015 Valentine Award Comes From The Heart and Goes To Famous New York Urologist 3Health News:Bird B Gone Offers Solutions to Bird Flu Threat to Poultry Farms 2Health News:Bird B Gone Offers Solutions to Bird Flu Threat to Poultry Farms 3Health News:Bird B Gone Offers Solutions to Bird Flu Threat to Poultry Farms 4Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 2Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 3Health News:Internationally Recognized British Indie Rock Outfit The 1975 Partner with Cadence & Cause to Provide Clean Drinking Water to Those in Need 2Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2
(Date:4/24/2015)... Allowing more basic emergency medical service (EMS) staff to ... opioids, according to a Centers for Disease Control and ... Medical Service Providers and the Burden of Drug Overdose ... of Public Health . In 2013, more ... involved prescription opioids, and more than 8,000 ...
(Date:4/24/2015)... 24, 2015 In today,s ever-changing and ... around the world to access diverse skill sets, ... there are many areas to misstep in the ... best practices are necessary and beneficial in order ... According to research by benchmarking firm, Best Practices, ...
(Date:4/24/2015)... , Apr. 24, 2015 Research and ... announced the addition of the "Lab ... tips/ Pumps/Microplate/Reagent Reservoir/Valve/Tubing/Wash Station) & End User ... Global Forecast to 2020" report to ... accessories market is expected to reach $504.7 ...
Breaking Medicine Technology:Expanding Naloxone use could reduce drug overdose deaths and save lives 2Expanding Naloxone use could reduce drug overdose deaths and save lives 3Work Around the Clock: Building Effective Global Capabilities 2Global Lab Accessories Market Report 2015-2020 - Label Printer/ Pipette tips/ Pumps/Microplate/Reagent Reservoir/Valve/Tubing/Wash Station 2Global Lab Accessories Market Report 2015-2020 - Label Printer/ Pipette tips/ Pumps/Microplate/Reagent Reservoir/Valve/Tubing/Wash Station 3
Cached News: