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Exercise and weight loss reduces excess insulin and lowers blood pressure in Syndrome X

The researchers measured blood pressure, glucose, insulin and lipid levels before, and six months after, the interventions.

In both of the intervention groups, the researchers found a reduction in hyperinsulinemia, In addition, in the group that combined exercise and weight loss, the researchers also found a significant reduction in diastolic blood pressure from 96 to 87 mm of mercury. Blood pressure did drop in the exercise-only group, but not significantly, from 93 to 89 mm of mercury.

The researchers said their findings are consistent with the National Cholesterol Education Program expert panel which reported in 2001 in the Journal of the American Medical Association that weight loss and exercise are valuable forms of treatment for Syndrome X.

"Our results also suggest that combining exercise with weight loss programs will likely reduce both hyperinsulinemia and high blood pressure in overweight men and women with Syndrome X," Watkins said. "Exercise without weight loss is likely to result in more limited improvements in risk factors associated with Syndrome X."


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Contact: Richard Merritt
merri006@mc.duke.edu
919-684-4148
Duke University Medical Center
8-Sep-2003


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