HOME >> MEDICINE >> NEWS
Experimental drugs show promise in halting brain tumors

BOSTON -- Researchers at the Duke Comprehensive Cancer Center have shown that four new and experimental drugs can strongly inhibit the growth of deadly brain tumors in animals, and they expect these promising results to hold true in humans, as well.

In fact, one of the drugs -- ZD6474 -- significantly slowed the growth of three different types of brain tumors, a remarkable finding given that brain tumors are very distinct in their biologic makeup, said Jeremy Rich, M.D., an assistant professor of medicine in the Brain Tumor Center at Duke.

"Despite our best efforts in the laboratory and the clinic, the survival rate for glioblastoma -- the most common and lethal brain tumor -- hasn't changed in 10 years, said Rich. "This new class of drugs has shown great promise in treating human tumors that were grown in mice, and we feel these results are indicative of how the drugs may act in humans."

Rich will present results of the three studies -- funded by the Pediatric Brain Tumor Foundation and ABC2 -- at the Molecular Targets and Cancer Therapeutics Meeting in Boston Nov. 17-21, 2003.

Each of the new drugs is designed to aim for a specific target within brain cancer cells, as opposed to the current strategy in which the body is indiscriminately bombarded with chemotherapy --the so called "sledgehammer" approach, said Rich. Tumors are often resistant to chemotherapy, and patients can suffer unpleasant side effects due to its toxicity.

The new drugs selectively target particular molecules within brain tumors, so they should be more effective inhibitors of tumor growth and carry far fewer side effects for the patient, said Rich.

Moreover, the selective nature of the new drugs means they will target different types of tumors, each of which exhibits its own unique characteristics. Thus, doctors will be able to customize therapy based on each individual's tumor type.

"Brain tumors are very diverse in their molecular makeup
'"/>

Contact: Becky Levine
levin005@mc.duke.edu
919-684-4148
Duke University Medical Center
20-Nov-2003


Page: 1 2 3 4

Related medicine news :

1. St. Jude scientist wins International Society of Experimental Hematology award
2. Experimental drug improves sleep in older patients, Wake Forest Baptist study shows
3. Experimental drug used to treat recurrent ovarian cancer shows promising results
4. Experimental treatment yields new hope for children battling cerebral palsy
5. Experimental drugs reduce neuron death in rats following insulin shock
6. Experimental pill found to improve symptoms in patients with non-small-cell lung cancer
7. Experimental drug reverses effects of Fabry disease in mice
8. Experimental peptides prevent diabetes and halt its progression
9. Experimental testosterone patch shows promise for treating diminished sexual function in surgically menopausal women
10. Clinical Trial Demonstrates Experimental Growth Factor Increases Eligibility For Autologous Stem Cell Transplantation
11. UW research shows risk factors for relapse among health care professionals who abuse drugs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/10/2020)... ... July 10, 2020 , ... Inversion therapy is defined by Healthline.com, ... spine and relieve back pain.” Ergo, the theory is that if the body’s point ... traction for the spine using the head and upper body as the "weights" needed ...
(Date:7/10/2020)... ... 2020 , ... CellTrak, the leading electronic visit verification (EVV) ... of Medicaid has awarded CellTrak Phase 2 EVV certification as an alternative Electronic ... CellTrak for EVV – both as a point-of-care solution and to relay data ...
(Date:7/10/2020)... ... July 10, 2020 , ... NeoTract, a wholly owned subsidiary ... urology, today announced that Carl Meyer, M.D., The Iowa Clinic in West Des ... recognizes that Dr. Meyer has achieved a high level of training and experience ...
(Date:7/7/2020)... ... July 07, 2020 , ... Mediaplanet recently launched an awareness initiative ... pandemic thrust this field into the spotlight and, as a result, the Bureau ... 2026. In partnership with South University — which offers a Master’s in ...
(Date:7/7/2020)... ... 2020 , ... The Germ-Fogger™ disinfecting spray system with vortecular™ ... surfaces is now available in Mexico and Latin America. A new Spanish-language website, ... In this era of worldwide pandemic, the ability to rapidly and efficiently disinfect ...
Breaking Medicine News(10 mins):
(Date:7/7/2020)... (PRWEB) , ... July 07, 2020 , ... ... in 2017, the company began as a hair service provider. Now called Bright, ... and work-from-home employees. Bright’s expanded offering includes beauty amenities as well as an ...
(Date:7/2/2020)... ... July 02, 2020 , ... AllenComm, the leader in ... four Omni Awards for visually compelling compliance training , onboarding , ... and exceed client and industry expectations as a digital transformation partner for learning and ...
(Date:7/2/2020)... ... July 02, 2020 , ... Realty ONE Group International, one ... on its live agent Town Halls, furthering its commitment to its real estate ... special guests and Realty ONE Group leadership discussing social, mental, physical and financial ...
Breaking Medicine Technology:
Cached News: