HOME >> MEDICINE >> NEWS
Exposure to famine associated with increased breast cancer risk

Women who experienced a short but severe decrease in their food intake during the 19441945 Dutch famine have an increased risk of breast cancer compared with women whose caloric intake was not as greatly affected, according to a study in the April 7 issue of the Journal of the National Cancer Institute.

Several animal studies have found that reducing caloric intake by one-third to one-half for the animals' lifetime prevents various types of cancer, but the implications of short-term caloric restriction are largely unknown. However, reproducing these types of studies in humans raises ethical and practical issues.

During World War II, a famine in the western part of The Netherlands resulted from a food embargo imposed by German authorities. Between 1983 and 1986, about 15,000 women participating in a Dutch breast cancer screening program who were between ages 2 and 33 during the 19441945 famine responded to a questionnaire about their famine experience. Sjoerd G. Elias, Ph.D., of the Julius Center for Health Sciences and Primary Care at the University Medical Center Utrecht, The Netherlands, and colleagues used data gathered from these women to study the effects of the famine on subsequent breast cancer risk.

Women were given a famine exposure score--absent, moderate, or severe exposure to famine--based on information about hunger, cold, and weight loss. The risk of breast cancer increased with increasing severity of famine exposure. For example, women who experienced severe exposure to famine had a 48% increased risk of breast cancer compared with women who were not affected by the famine. The association between famine exposure and breast cancer risk was highest among women who were between ages 2 and 9 during the famine compared with women exposed at older ages. The risk was also stronger among women who never gave birth compared with women who had children.

Although a mechanism for the increased breast cancer risk among wom
'"/>

Contact: Katherine Arnold
jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute
6-Apr-2004


Page: 1 2

Related medicine news :

1. Exposure to food increases brain metabolism
2. Exposure to carcinogens not proportionally decreased by reduction in smoking
3. Exposure to atomic bomb radiation associated with nervous system tumors
4. Exposure to bacteria modulates immune response and decreases allergy in farm children
5. Exposure to hepatitis C has no effect on antiretroviral treatment outcomes in HIV patients
6. Exposure to light and sleep pattern alteration
7. Near-Sightedness In Children Linked To Light Exposure During Sleep Before Age Two
8. Repeated Exposure To Cocaine Alters Brain Structure
9. UB Oral Biologists Find Link Between Gum Disease And Passive Exposure To Tobacco Smoke
10. Despite Progress, More Action Needed To Protect Medical Students From Exposure To Disease Through Accidental Needlesticks, UCSF Study Finds
11. Prenatal Cocaine Exposure Leads To Lower Child IQ Scores, Language Skills

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Exposure famine associated with increased breast cancer risk

(Date:4/22/2014)... scientists have found a way to block abnormal cholesterol ... atherosclerosis, the main cause of heart attacks and strokes ... condition develops when fat builds inside blood vessels over ... reducing their ability to feed oxygen-rich blood to the ... of experiments, described April 7 in the journal ...
(Date:4/22/2014)... (SALT LAKE CITY)A computational tool developed at the University ... with unknown gene mutations in three separate cases, U ... new study in The American Journal of Human ... Re-ranking tool), identifies undiagnosed illnesses and unknown gene mutations ... proteins that code for genes are made, in individual ...
(Date:4/22/2014)... is available in German . ... of the University of Vienna and the Medical University of ... shown how double stranded RNA, such as viral genetic information, ... the immune response against viral infection, the protein ADAR1 moves ... modifies viral RNA to inhibit reproduction of the virus. But ...
(Date:4/22/2014)... influenced by low exposure to testosterone in the womb, ... men,s testosterone levels may be determined before they are ... the hormone than others is important because testosterone is ... hormone have been linked to obesity, diabetes and heart ... for producing testosterone in adults known as Leydig ...
(Date:4/22/2014)... waited in line and most of us have gotten ... like. , For Will Mather, assistant professor of ... Integrated Science Curriculum, studying lines, or queues, has been ... bottlenecks that limit the recycling of proteins. , The ... professor, has received attention from the National Science Foundation ...
Breaking Medicine News(10 mins):Health News:Scientists alter fat metabolism in animals to prevent most common type of heart disease 2Health News:Scientists alter fat metabolism in animals to prevent most common type of heart disease 3Health News:Scientists alter fat metabolism in animals to prevent most common type of heart disease 4Health News:Applying math to biology: Software identifies disease-causing mutations in undiagnosed illnesses 2Health News:Applying math to biology: Software identifies disease-causing mutations in undiagnosed illnesses 3Health News:How the body fights against viruses 2Health News:How the body fights against viruses 3Health News:Queuing theory helps physicist understand protein recycling 2
(Date:1/15/2014)... 15, 2014 Reportlinker.com announces that a ... its catalogue: Insulin ... http://www.reportlinker.com/p01957812/Insulin-Pump-Market--Forecast-–-Worldwide-Analysis.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Equipment_and_Supply ... Insulin Pumps are gaining strong ...
(Date:1/15/2014)...  Zafgen, Inc., a leading biopharmaceutical company dedicated to ... today announced initial results from its Phase 2a ... aminopeptidase 2 (MetAP2), in patients with Prader-Willi syndrome ... results showed improvements in body weight, hunger-related behaviors, ...
(Date:1/14/2014)... HILLS, Calif. , Jan. 14, 2014 The Brandeis Medical ... Los Angeles a premier and affordable laser tattoo removal ... special. Dr. Brandeis, focus is in providing high quality cosmetic services ... all patients. " Southern California has ...
Breaking Medicine Technology:Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2
Cached News: