HOME >> MEDICINE >> NEWS
Fat may promote inflammation, new study suggests

WINSTON-SALEM, N.C. Why does extra fat around the waist increase the risk of heart disease? A new study by Wake Forest University Baptist Medical Center researchers and colleagues suggests that inflammation may be the key.

"It is well known that obesity affects nearly one-third of adults in the United States and is closely linked with heart disease," said Tongjian You, Ph.D., instructor in geriatric medicine at Wake Forest Baptist and lead author. "While we don't fully understand the link between obesity and heart disease, our study suggests that inflammatory proteins produced by fat itself may play a role."

The study, to be published in the April issue of the American Journal of Physiology Endocrinology and Metabolism, evaluated whether inflammatory proteins produced by fat are linked to risk factors for heart disease, including high blood pressure, high cholesterol and how the body responds to insulin. The research is based on a new idea in medicine that fat is an "organ" that produces proteins and hormones that affect metabolism and health.

The researchers studied two proteins that promote inflammation (interleukin 6 and tumor necrosis factor alpha) and a protein that promotes blood clots (plasminogen activator inhibitor 1). These proteins are all manufactured by fat tissue and involved in atherosclerosis, the buildup of fatty deposits in the linings of blood vessels. In addition, the scientists also looked at two "good" proteins, leptin, which regulates energy metabolism, and adiponectin, which has anti-inflammatory effects.

To gauge production levels of the proteins, the scientists took small samples of subcutaneous fat, which is just under the skin, from the abdomen and measured levels of messenger RNA (mRNA), which carries the genetic code instructions for cells to create the proteins.

The study included 20 post-menopausal women from 50 to 70 years old who were overweight or obese and had waists larger than 35 inche
'"/>

Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-4453
Wake Forest University Baptist Medical Center
28-Mar-2005


Page: 1 2 3

Related medicine news :

1. AACC and The Endocrine Society partner to promote patient education
2. Protein that promotes survival of stem cells might be key to poor leukemia prognosis
3. Regular family meals promote healthy eating habits
4. Protein not only aids nerve development, but promotes blood vessel growth, too
5. First solid evidence that the study of music promotes intellectual development
6. Conference promotes breast and cervical cancer awareness in Nigeria
7. Fox Chase Cancer Center and the Girl Scouts partner to promote oncology nursing careers
8. Protein promotes cancer metastasis and survival
9. Ultrasound treatment for hurt muscles may feel good, but doesnt promote healing, study suggests
10. Adams Respiratory Therapeutics and Hollister-Stier Laboratories to co-promote ALLERx(TM) dose pack
11. Before and after diet ads promote bias against overweight people

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/20/2020)... ... February 20, 2020 , ... R3 Medical Training announced ... Nevada. Providers will learn how to perform injections for all large and small joints ... to learn from online videos. The best opportunity is to perform injections in a ...
(Date:2/19/2020)... Conn. (PRWEB) , ... February 19, 2020 , ... ... periodontists at Advanced Periodontics and Dental Implant Center of Connecticut, celebrate 30 years ... new patients with the same low fees that they charged in 1989, only ...
(Date:2/19/2020)... ... February 19, 2020 , ... BPM+ ... delivery, announced that it will participate in the HIMSS20 Global Health ... will engage healthcare professionals and other stakeholders at HIMSS20 – the largest global ...
(Date:2/16/2020)... ... February 16, 2020 , ... Canadian digital healthcare portal Ask The ... who are concerned about the Coronavirus. , "It is our duty and it is ... this deadly virus" said Prakash Chand, CEO of Ask The Doctor. , Doctors and ...
(Date:2/14/2020)... ... ... The Dr. Oz Show is an American daytime television talk show, hosted by ... an upcoming guest on the show, New York City plastic surgeon and ... the segment, Dr. Linkov, a leader and trusted authority on hair loss, provides guidance ...
Breaking Medicine News(10 mins):
(Date:2/14/2020)... ... 2020 , ... Dignitana AB , world leader in scalp cooling innovation, ... sponsor three signature events in 2020 with Susan G. Komen®. The sponsorship extends Dignitana’s ... the Cure® and MORE THAN PINK Walk® events in key Dignitana markets throughout year. ...
(Date:2/14/2020)... ... 14, 2020 , ... Gramercy Dental Center , located at 118 East ... offers an expansive menu of dental services in one convenient location. Dr. Mark Don ... an esteemed cosmetic and restorative dentist Dr. Patricia Sciortino. Together, they are equipped to ...
(Date:2/14/2020)... ... 2020 , ... Group Health Dental , located at 230 W 41st ... range of dental services under one roof. The midtown practice has recently earned the ... Doctors . Find Local Doctors is a trusted online directory that recognizes physicians and ...
Breaking Medicine Technology:
Cached News: