HOME >> MEDICINE >> NEWS
Fat may promote inflammation, new study suggests

WINSTON-SALEM, N.C. Why does extra fat around the waist increase the risk of heart disease? A new study by Wake Forest University Baptist Medical Center researchers and colleagues suggests that inflammation may be the key.

"It is well known that obesity affects nearly one-third of adults in the United States and is closely linked with heart disease," said Tongjian You, Ph.D., instructor in geriatric medicine at Wake Forest Baptist and lead author. "While we don't fully understand the link between obesity and heart disease, our study suggests that inflammatory proteins produced by fat itself may play a role."

The study, to be published in the April issue of the American Journal of Physiology Endocrinology and Metabolism, evaluated whether inflammatory proteins produced by fat are linked to risk factors for heart disease, including high blood pressure, high cholesterol and how the body responds to insulin. The research is based on a new idea in medicine that fat is an "organ" that produces proteins and hormones that affect metabolism and health.

The researchers studied two proteins that promote inflammation (interleukin 6 and tumor necrosis factor alpha) and a protein that promotes blood clots (plasminogen activator inhibitor 1). These proteins are all manufactured by fat tissue and involved in atherosclerosis, the buildup of fatty deposits in the linings of blood vessels. In addition, the scientists also looked at two "good" proteins, leptin, which regulates energy metabolism, and adiponectin, which has anti-inflammatory effects.

To gauge production levels of the proteins, the scientists took small samples of subcutaneous fat, which is just under the skin, from the abdomen and measured levels of messenger RNA (mRNA), which carries the genetic code instructions for cells to create the proteins.

The study included 20 post-menopausal women from 50 to 70 years old who were overweight or obese and had waists larger than 35 inche
'"/>

Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-4453
Wake Forest University Baptist Medical Center
28-Mar-2005


Page: 1 2 3

Related medicine news :

1. AACC and The Endocrine Society partner to promote patient education
2. Protein that promotes survival of stem cells might be key to poor leukemia prognosis
3. Regular family meals promote healthy eating habits
4. Protein not only aids nerve development, but promotes blood vessel growth, too
5. First solid evidence that the study of music promotes intellectual development
6. Conference promotes breast and cervical cancer awareness in Nigeria
7. Fox Chase Cancer Center and the Girl Scouts partner to promote oncology nursing careers
8. Protein promotes cancer metastasis and survival
9. Ultrasound treatment for hurt muscles may feel good, but doesnt promote healing, study suggests
10. Adams Respiratory Therapeutics and Hollister-Stier Laboratories to co-promote ALLERx(TM) dose pack
11. Before and after diet ads promote bias against overweight people

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/8/2019)... ... , ... Cognosante has been awarded a contract to continue ... Referrals and Authorizations program. The new task order will allow Cognosante ... enterprise-wide system used by community care staff to generate referrals and authorizations for ...
(Date:10/8/2019)... ... October 08, 2019 , ... As a world-renowned expert using ... professor with the University of Maryland Department of Veterinary Medicine, continues to make ... Shi and his lab have discovered a new pathway by which liver macrophages ...
(Date:10/8/2019)... ... ... Over the past three decades, Buffalo Wings & Rings has elevated the ... providing a higher-quality product and experience than the competition. Now, the club-level sports restaurant ... MUG FOR THE CAUSE" campaign in support of Breast Cancer Awareness Month. , ...
(Date:10/8/2019)... ... 08, 2019 , ... METAvivor Research and Support Inc., a non-profit organization dedicated ... Stage IV Stampede campaign. The campaign will commence with two days of action and ... advocacy boot camp, a march, a Die-In (hosted by partner MET-UP), and visits with ...
(Date:10/8/2019)... ... October 08, 2019 , ... The University of ... Digital Health Awards 1st Round (Top Ten) Finalist in its Best Cardiovascular Digital ... companies that promote faster, better, more cost-effective healthcare by improving outcomes such as ...
Breaking Medicine News(10 mins):
(Date:10/8/2019)... ... , ... Fresno resident Regina Tanner has been selected by Donate Life ... will walk alongside the float, Light in the Darkness, during the 131st Tournament of ... a living organ donor in the fall of 2016 when her husband, Cary, was ...
(Date:10/8/2019)... ... October 08, 2019 , ... ... face in her book, Miracle Baby: A Fertility Doctor’s Fight for Motherhood (Brown ... and fertility specialist, Noorhasan writes to educate, encourage, advise and support people who ...
(Date:10/8/2019)... HOUSTON (PRWEB) , ... October 08, 2019 , ... ... compliance (GRC) software as a service (SaaS) platform, today announced integration between the ... reduces the average time it takes medical office staff to obtain peer references ...
Breaking Medicine Technology:
Cached News: