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Faulty gene may explain why some fall ill at high altitudes

rried the Glu298Asp variation compared to 25.6 percent of the HAPE patients. Variations at the 27-bp VNTR site on the gene occurred in 6.9 percent of the control group and in 23.2 percent of the HAPE patients.

The researchers then investigated how many of the 92 participants had both variations. They found that 26.8 percent of the HAPE group, but none of the control group, carried the two polymorphisms.


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Contact: Maggie Francis
maggie.francis@heart.org
214-706-1397
American Heart Association
22-Jul-2002


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