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Feeding your fat

little or no evidence for the PSNS innervation of white adipose tissue" noted Timothy Bartness from the Department of Biology and Center for Behavioral Neuroscience at Georgia State University, Atlanta, in his accompanying Commentary in the JCI. The authors also demonstrated that individual neurons are specialized to control one fat compartment. Dr. Bartness writes further "this could result in enhanced regional accumulation of lipid with certain pathologies. This expansion of the adipose organ in these areas could lead to several well-known adverse health consequences of enhanced visceral/abdominal adiposity such as type II diabetes, certain cancers and high blood pressure." However more work is necessary to reveal whether the nerves described participate in naturally-occurring lipid accumulation, or alternatively are associated with disease-related obesity states.


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Contact: Brooke Grindlinger
science_editor@the-jci.org
212-342-9006
Journal of Clinical Investigation
5-Nov-2002


Page: 1 2

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