HOME >> MEDICINE >> NEWS
First head-to-head study to compare lidoderm patch and Celebrex in treating pain

CHADDS FORD, Pa., March 31, 2005 Today at the 24th Annual Scientific Meeting of the American Pain Society, Endo Pharmaceuticals Inc. released new clinical trial data which found patients receiving either Lidoderm (lidocaine patch 5%) or Celebrex (celecoxib) 200 mg for pain associated with osteoarthritis (OA) of the knee experienced improvement in average daily pain intensity. Lidoderm is a topical analgesic patch approved by the U.S. Food and Drug Administration (FDA) in 1999 to treat the pain associated with post-herpetic neuralgia (PHN), a chronic condition resulting from nerve damage caused by shingles.

"The results of this exploratory study examining Lidoderm and Celebrex suggest that Lidoderm can alleviate the pain associated with osteoarthritis of the knee," said Alan Kivitz, M.D., of Altoona (Pa.) Center for Clinical Research. "I am encouraged by these findings since there is a critical need for new approaches to managing this type of pain."

OA affects more than 20 million Americans annually and generates more than seven million physician visits per year. If left untreated, chronic pain conditions such as OA can have significant physical, psychological and financial consequences by affecting daily functioning and quality of life.

Due to safety concerns regarding the entire COX-II inhibitor class in the fall of 2004, the sponsor of the study, Endo Pharmaceuticals Inc., voluntarily elected to prematurely halt the study prior to reaching the original enrollment target. However an analysis of data after six weeks of treatment showed that of the patients treated in the Lidoderm group (N=56), 54% experienced a 30% or greater improvement in average daily pain intensity; (studies have reported that 30% or greater reductions in pain intensity are clinically meaningful to pain patients). In the Celebrex group (N=63), 62% experienced a 30% or greater improvement in average daily pain intensity. In addition, clinically meaningfu
'"/>

Contact: Fiona Buraimoh
fiona_buraimoh@nyc.cohnwolfe.com
212-798-9512
Cohn & Wolfe
31-Mar-2005


Page: 1 2 3

Related medicine news :

1. First UK cases of previously rare disease reported in gay men
2. First mouse model for multiple system atrophy points to new treatment targets for brain diseases
3. Mayo Clinic researchers create obedient virus; First step to use measles virus against cancer
4. First US kidney cancer vaccine trial underway at Columbia
5. First new treatment for alcoholism in ten years, now available Campral(R) (acamprosate calcium)
6. First blood test to diagnose paralyzing, blinding disease
7. First US SARS vaccine trial opens at NIH
8. First-ever safety study of medical cannabis use in Canada launched
9. First solid evidence that the study of music promotes intellectual development
10. First medical test on CD gets good results
11. First proof that cutting Rx drugs due to cost harms health

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/11/2018)... ... August 10, 2018 , ... Johns Hopkins All Children’s Hospital will make ... by utilizing a population health perspective on care. At its core, this perspective focuses ... treated at the right facility or setting at the right cost. Mark Douglas "Doug" ...
(Date:8/9/2018)... ... August 09, 2018 , ... ... LegitScript is a new verification process that substance abuse providers must pass in ... means we can reach more people to help.” , Helping people is ...
(Date:8/7/2018)... ... August 07, 2018 , ... Sussex Vision Center, a multi-site optometry ... Michael Sussex, OD, founded the practice in Coldwater, and over the last three decades ... OD, to offer comprehensive eye health services for patients of all ages. , ...
(Date:8/3/2018)... Texas (PRWEB) , ... August 03, 2018 , ... Yisrayl ... this week that reveals secret passages and meanings from the Bible meant only to ... studying Bible Prophecy and he has been able to decode passages that he says ...
(Date:8/2/2018)... ... 2018 , ... The EndBrainCancer Initiative (EBCI, formerly the Chris ... caregiver and patient clinical trials at the Pacific Neuroscience Institute and John Wayne ... the Pacific Neuroscience Institute and John Wayne Cancer Institute , ...
Breaking Medicine News(10 mins):
(Date:8/2/2018)... ... August 02, 2018 , ... ... with customer relationship management (CRM), patient experience and provider communication solutions for ... Program for Health Information Service Providers (HISPs). DirectTrust is a ...
(Date:8/2/2018)... , ... August 01, 2018 , ... ... to announce the launch of its healthcare ecosystem that will be fuelled by ... make its platform available to the public and commence its token sale September ...
(Date:8/2/2018)... ... ... The Team from Hennessey Performance (HPE) has built and tuned their 10,000 vehicle. ... commemorative vehicle: The 2019 Hennessey Heritage Edition Mustang. Inspired by the 2018 ... at 7,200 rpm and 677 lb-ft of torque at 4,500 rpm. The Hennessey ...
Breaking Medicine Technology:
Cached News: