HOME >> MEDICINE >> NEWS
First head-to-head study to compare lidoderm patch and Celebrex in treating pain

CHADDS FORD, Pa., March 31, 2005 Today at the 24th Annual Scientific Meeting of the American Pain Society, Endo Pharmaceuticals Inc. released new clinical trial data which found patients receiving either Lidoderm (lidocaine patch 5%) or Celebrex (celecoxib) 200 mg for pain associated with osteoarthritis (OA) of the knee experienced improvement in average daily pain intensity. Lidoderm is a topical analgesic patch approved by the U.S. Food and Drug Administration (FDA) in 1999 to treat the pain associated with post-herpetic neuralgia (PHN), a chronic condition resulting from nerve damage caused by shingles.

"The results of this exploratory study examining Lidoderm and Celebrex suggest that Lidoderm can alleviate the pain associated with osteoarthritis of the knee," said Alan Kivitz, M.D., of Altoona (Pa.) Center for Clinical Research. "I am encouraged by these findings since there is a critical need for new approaches to managing this type of pain."

OA affects more than 20 million Americans annually and generates more than seven million physician visits per year. If left untreated, chronic pain conditions such as OA can have significant physical, psychological and financial consequences by affecting daily functioning and quality of life.

Due to safety concerns regarding the entire COX-II inhibitor class in the fall of 2004, the sponsor of the study, Endo Pharmaceuticals Inc., voluntarily elected to prematurely halt the study prior to reaching the original enrollment target. However an analysis of data after six weeks of treatment showed that of the patients treated in the Lidoderm group (N=56), 54% experienced a 30% or greater improvement in average daily pain intensity; (studies have reported that 30% or greater reductions in pain intensity are clinically meaningful to pain patients). In the Celebrex group (N=63), 62% experienced a 30% or greater improvement in average daily pain intensity. In addition, clinically meaningfu
'"/>

Contact: Fiona Buraimoh
fiona_buraimoh@nyc.cohnwolfe.com
212-798-9512
Cohn & Wolfe
31-Mar-2005


Page: 1 2 3

Related medicine news :

1. First UK cases of previously rare disease reported in gay men
2. First mouse model for multiple system atrophy points to new treatment targets for brain diseases
3. Mayo Clinic researchers create obedient virus; First step to use measles virus against cancer
4. First US kidney cancer vaccine trial underway at Columbia
5. First new treatment for alcoholism in ten years, now available Campral(R) (acamprosate calcium)
6. First blood test to diagnose paralyzing, blinding disease
7. First US SARS vaccine trial opens at NIH
8. First-ever safety study of medical cannabis use in Canada launched
9. First solid evidence that the study of music promotes intellectual development
10. First medical test on CD gets good results
11. First proof that cutting Rx drugs due to cost harms health

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/6/2019)... ... ... TIME For Kids (TFK) revealed the first-ever list of the World’s ... that are tailored to the interests of kids. The list identifies The Children’s Museum ... TIME for Kids gathered nominations from its network of TFK Kid Reporters ...
(Date:12/5/2019)... ... December 05, 2019 , ... HealthCareMandA.com is hosting an interesting ... on Thursday, December 12, 2019, at 1:00 PM ET. , Private equity firms ... firms are scrambling to assemble regional platforms with enough scale and talent to ...
(Date:12/4/2019)... ... December 04, 2019 , ... A November 12 ... cities offer them as public transit options. The article highlighted the life-changing or life-ending ... confined to a bed to a rider fatality after an incident with a vehicle. ...
(Date:12/4/2019)... ... ... While the holidays are a time for joy and sharing, they can ... Service specialists. , “There are many behavioral and logistical changes you ... Joyce Cavanagh, AgriLife Extension specialist in family economics, College Station. , Prioritize and plan ...
(Date:12/2/2019)... ... 02, 2019 , ... TrialScope, the global leader in clinical ... American branch of the healthcare business of Merck KGaA, Darmstadt, Germany, to launch ... inform patients, caregivers, the public, patient advocacy groups and healthcare professionals (HCPs) about ...
Breaking Medicine News(10 mins):
(Date:12/4/2019)... ... 2019 , ... The Harm Reduction Institute (HRI) as a part of the ... rehab center and non-profit Intensive outpatient after care (IOP) , has officially ... distributed Naloxone amongst members of the own community in Orange County, CA. , ...
(Date:12/4/2019)... ... December 04, 2019 , ... Intelligent.com, a ... Top 17 Master's in Organizational Psychology Degree Programs for 2020. The comprehensive research ... the nation. Each program is evaluated based on curriculum quality, graduation rate, reputation, ...
(Date:12/2/2019)... ... December 02, 2019 , ... TopConsumerReviews.com ... by Native Remedies aimed at supporting Women’s Fertility and healthy natural ovulation. , ... harder for some women than for others. Factors like weight, medical conditions, age, ...
Breaking Medicine Technology:
Cached News: