HOME >> MEDICINE >> NEWS
First-line use of voriconazole yields better outcomes for life-threatening fungal infection

San Antonio (Sept. 16, 2003) Data presented at the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) showed that the antifungal treatment voriconazole, a second-generation triazole, is more effective and less costly than the standard of care for invasive aspergillosis when used as first-line therapy (Posters M-964 and A-1359). Results from global studies were presented by The University of Texas Health Science Center at San Antonio (UTHSCSA) researchers, Thomas F. Patterson, M.D., professor of medicine, and James Lewis, Pharm.D., infectious diseases pharmacy specialist.

"For patients whose immune systems are compromised by cancer chemotherapy or organ and bone marrow transplants, invasive aspergillosis can be fatal," said Dr. Patterson. "Physicians need to understand that the type of therapy selected for first line impacts the patient's chance of survival. These studies showed that patients initially treated with voriconazole had better outcomes and incurred fewer antifungal drug costs than patients treated initially with the prior 'gold standard therapy' amphotericin B."

Enhancing Patient Outcome

Dr. Patterson and other investigators assessed how initial therapy with voriconazole impacts ultimate outcomes compared to amphotericin B. This analysis was done with data from a previously published clinical trial (Herbrecht, NEJM, 2002) that compared voriconazole to standard therapy with amphotericin B. The study (Poster M-964) assessed 277 patients who were randomized to either voriconazole or amphotericin B and treated for up to 12 weeks.

The results showed that initial treatment with voriconazole led to significantly better outcomes for patients compared to those treated initially with amphotericin B. Overall, voriconazole patients had a 53 percent success rate as compared to success in 32 percent of patients on amphotericin B. Notably success occurred in only 23 percent who were switched from
'"/>

Contact: Will Sansom
210-567-2579
Edelman Public Relations
16-Sep-2003


Page: 1 2 3

Related medicine news :

1. Research in yeast yields missing link in DNA maintenance machinery
2. Research with red tide toxin yields potential therapies for cystic fibrosis
3. Initiative yields effective methods for anthrax detection; RAMP and MIDI, Inc., methods approved
4. Cryogenics research yields possible cure for arrhythmia
5. Intensive diabetes management yields positive results, according to Pittsburgh project
6. Experimental treatment yields new hope for children battling cerebral palsy
7. Database study yields new insights into arthritis drug
8. Computer design yields better, more efficient therapeutic for preventing tissue damage
9. Computer tool yields higher self-reports of key HIV risk behaviors by Zimbabwean women
10. SNM collaboration yields diagnostic nuclear medicine guide for compliance with NRC regulations
11. Brain study of back pain sufferers yields intriguing results

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2019)... ... , ... With Valentine’s Day tomorrow and love in the air, myLAB ... tips to ensure ‘Safe Sex’: , 1. Talk To Your Partner. Communication is ... Having clear, open, and honest communication is key so that both partners are able ...
(Date:2/13/2019)... ... 2019 , ... Infertility is an issue for 1 in 6 couples; in about 50% of ... the sharp decline in male sperm count over the last 40 years was featured in ... causing panic that we are in the midst of a severe, perhaps irreversible, male infertility ...
(Date:2/13/2019)... ... February 13, 2019 , ... Surgery that moves both jaws forward – known ... sleep apnea (OSA), resulting in benefits that include improved breathing, daytime wakefulness and quality ... , MMA should be regarded as the preferred treatment for patients with moderate to ...
(Date:2/12/2019)... ... February 12, 2019 , ... ... organization, devoted to helping hospital leaders, staff, and physicians achieve excellence, announced ... The website now features a streamlined design, improved functionality, and robust insights ...
(Date:2/12/2019)... ... February 12, 2019 , ... Surgical Theater is ... satisfaction, improve patient retention, and reduce patient outmigration for attendees of the Healthcare ... provides Surgical Theater with a great venue to highlight the value of patient ...
Breaking Medicine News(10 mins):
(Date:2/16/2019)... Minn. (PRWEB) , ... February 15, 2019 , ... ... Safety and Health Achievement Recognition Program (MNSHARP) award for safety excellence. Commissioner Kristin ... Peter, Minnesota the respected award. , Safety is more than just a set ...
(Date:2/16/2019)... ... February 15, 2019 , ... ... studies and patient registries demonstrating the value of SelectMDx and ConfirmMDx for Prostate ... Cancers Symposium (ASCO GU), taking place in San Francisco, California from February 14-16, ...
(Date:2/14/2019)... ... February 14, 2019 , ... ... certified reproductive endocrinologist, Dr. Desireé McCarthy-Keith has been named Medical Director ... and dedication to the practice and the local Atlanta community in helping patients ...
Breaking Medicine Technology:
Cached News: