HOME >> MEDICINE >> NEWS
First-line use of voriconazole yields better outcomes for life-threatening fungal infection

San Antonio (Sept. 16, 2003) Data presented at the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) showed that the antifungal treatment voriconazole, a second-generation triazole, is more effective and less costly than the standard of care for invasive aspergillosis when used as first-line therapy (Posters M-964 and A-1359). Results from global studies were presented by The University of Texas Health Science Center at San Antonio (UTHSCSA) researchers, Thomas F. Patterson, M.D., professor of medicine, and James Lewis, Pharm.D., infectious diseases pharmacy specialist.

"For patients whose immune systems are compromised by cancer chemotherapy or organ and bone marrow transplants, invasive aspergillosis can be fatal," said Dr. Patterson. "Physicians need to understand that the type of therapy selected for first line impacts the patient's chance of survival. These studies showed that patients initially treated with voriconazole had better outcomes and incurred fewer antifungal drug costs than patients treated initially with the prior 'gold standard therapy' amphotericin B."

Enhancing Patient Outcome

Dr. Patterson and other investigators assessed how initial therapy with voriconazole impacts ultimate outcomes compared to amphotericin B. This analysis was done with data from a previously published clinical trial (Herbrecht, NEJM, 2002) that compared voriconazole to standard therapy with amphotericin B. The study (Poster M-964) assessed 277 patients who were randomized to either voriconazole or amphotericin B and treated for up to 12 weeks.

The results showed that initial treatment with voriconazole led to significantly better outcomes for patients compared to those treated initially with amphotericin B. Overall, voriconazole patients had a 53 percent success rate as compared to success in 32 percent of patients on amphotericin B. Notably success occurred in only 23 percent who were switched from
'"/>

Contact: Will Sansom
210-567-2579
Edelman Public Relations
16-Sep-2003


Page: 1 2 3

Related medicine news :

1. Research in yeast yields missing link in DNA maintenance machinery
2. Research with red tide toxin yields potential therapies for cystic fibrosis
3. Initiative yields effective methods for anthrax detection; RAMP and MIDI, Inc., methods approved
4. Cryogenics research yields possible cure for arrhythmia
5. Intensive diabetes management yields positive results, according to Pittsburgh project
6. Experimental treatment yields new hope for children battling cerebral palsy
7. Database study yields new insights into arthritis drug
8. Computer design yields better, more efficient therapeutic for preventing tissue damage
9. Computer tool yields higher self-reports of key HIV risk behaviors by Zimbabwean women
10. SNM collaboration yields diagnostic nuclear medicine guide for compliance with NRC regulations
11. Brain study of back pain sufferers yields intriguing results

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: