HOME >> MEDICINE >> NEWS
For leg-bypass patients, drugs can save lives and limbs, but many patients go without them

ANN ARBOR, MI The same drugs that help millions of heart patients can also aid people who have painful blockages in the blood vessels of their legs, new research from the University of Michigan Cardiovascular Center shows.

Drugs called statins and ACE inhibitors can save those patients' lives, or their limbs, if they take the medications before having a leg bypass operation, the study finds.

But the U-M researchers found that only about half of patients whose leg vessel disease has progressed far enough to require a bypass operation are actually taking the potentially beneficial drugs.

The results, published in the February issue of the Journal of Vascular Surgery, suggest that vascular surgeons should make sure their patients are receiving appropriate drugs before performing leg bypass surgery to re-route blood flow around a severely clogged leg artery.

"What we found surprised us," says lead author and U-M vascular surgeon Peter Henke, M.D. "Patients who were taking statins before their leg bypass operation had better patency, or openness, of their bypass graft, and a lower risk of leg amputation after surgery. Those taking ACE inhibitors had a lower risk of dying after the operation. And the effect of the medications far outweighed the effects of the patients' PAD severity, other medical problems, or the type of graft used."

An estimated 12 million Americans have peripheral arterial disease, or PAD, in which clogged or stiffened leg arteries cause pain during walking or rest. Left untreated, PAD can cause non-healing wounds and gangrene, and can led to amputation unless the blocked area is opened or bypassed. It's also associated with a high risk of heart attack and stroke.

The new U-M study looked at the usage rates and effects of statins and ACE inhibitors in 293 patients with advanced PAD who had open-leg bypass operations at the U-M Health System between 1997 and 2002. Average follow-up was 17 month
'"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
27-Jan-2004


Page: 1 2 3 4

Related medicine news :

1. New female sterilization technique not only quicker and easier for patients, but cheaper
2. ACE inhibitors not needed for many heart disease patients, according to new study
3. Clerks control healthcare access for uninsured patients, study finds
4. Experimental drug improves sleep in older patients, Wake Forest Baptist study shows
5. Time with patients, staff support boost flu shot rates
6. Insulin decreases inflammation, aids clot-busting drugs in heart attack patients, UB study shows
7. Diabetes management improves when patients, doctors agree on treatment goals, UMHS study finds
8. Gastric bypass surgery resolves or improves diabetes in most patients, reports Pittsburgh study
9. HIV infection may bump up risk of heart disease in younger patients, UCLA study finds
10. Web knowledge empowers patients, researcher says
11. Possible new cancer therapy shrinks tumors in melanoma patients, Science authors report

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/27/2017)... ... February 27, 2017 , ... Anahata Ananda of Shamangelic ... happy to announce her “Spring Rejuvenation in Sedona” personally tailored retreats. For those ... the winter-weary soul an excellent opportunity to come out of hibernation and do ...
(Date:2/27/2017)... ... February 27, 2017 , ... This webinar ... analysis as a tool to characterize particle size distributions in the field of ... results and novel scientific findings. It describes methods of optimized and standardized sample ...
(Date:2/27/2017)... San Francisco, CA (PRWEB) , ... February 27, ... ... Area center for hair transplantation therapy, is proud to announce a new informational ... popular hair therapy procedures. Follicular Unit Extraction (FUE) hair transplant and Follicular Unit ...
(Date:2/26/2017)... ... February 26, 2017 , ... This is an ... world’s first to be ISO/IEC 17025:2005 INAB accredited for Der p 1 (house ... is the globally recognised standard that sets out requirements for the technical competence ...
(Date:2/26/2017)... (PRWEB) , ... February 26, 2017 , ... ODH, Inc.™ ... Care Summit, February 27-28 at the Sheraton Pentagon City Hotel in Arlington, VA. ODH’s ... PerformCARE to use behavioral health analytics to improve Medicaid population health management. , ODH ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... A recent research report published by Grand View Research, ... to reach a value of $55.8 billion by 2025. Earlier in ... have legalized marijuana for medical uses. In 2016, states such as ... North Dakota , Ohio and ... in medical applications such as chemotherapies and pain management. The growing ...
(Date:2/27/2017)... and PETACH TIKVAH, Israel , Feb. ... BCLI), a leading developer of adult stem cell technologies ... June S. Almenoff , M.D., Ph.D., FACP, and ... of Directors.  "Dr. Almenoff and Mr. ... come at an exciting time for our company," said ...
(Date:2/24/2017)... WOBURN, Mass. , Feb. 24, 2017 /PRNewswire/ ... that US dental labs have a new path ... abutments using the Biodenta implant library integrated into ... labs must implement FDA compliant Good Manufacturing Processes ... sub-contract manufacturer with Biodenta, and complete an audit ...
Breaking Medicine Technology:
Cached News: