HOME >> MEDICINE >> NEWS
For leg-bypass patients, drugs can save lives and limbs, but many patients go without them

ANN ARBOR, MI The same drugs that help millions of heart patients can also aid people who have painful blockages in the blood vessels of their legs, new research from the University of Michigan Cardiovascular Center shows.

Drugs called statins and ACE inhibitors can save those patients' lives, or their limbs, if they take the medications before having a leg bypass operation, the study finds.

But the U-M researchers found that only about half of patients whose leg vessel disease has progressed far enough to require a bypass operation are actually taking the potentially beneficial drugs.

The results, published in the February issue of the Journal of Vascular Surgery, suggest that vascular surgeons should make sure their patients are receiving appropriate drugs before performing leg bypass surgery to re-route blood flow around a severely clogged leg artery.

"What we found surprised us," says lead author and U-M vascular surgeon Peter Henke, M.D. "Patients who were taking statins before their leg bypass operation had better patency, or openness, of their bypass graft, and a lower risk of leg amputation after surgery. Those taking ACE inhibitors had a lower risk of dying after the operation. And the effect of the medications far outweighed the effects of the patients' PAD severity, other medical problems, or the type of graft used."

An estimated 12 million Americans have peripheral arterial disease, or PAD, in which clogged or stiffened leg arteries cause pain during walking or rest. Left untreated, PAD can cause non-healing wounds and gangrene, and can led to amputation unless the blocked area is opened or bypassed. It's also associated with a high risk of heart attack and stroke.

The new U-M study looked at the usage rates and effects of statins and ACE inhibitors in 293 patients with advanced PAD who had open-leg bypass operations at the U-M Health System between 1997 and 2002. Average follow-up was 17 month
'"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
27-Jan-2004


Page: 1 2 3 4

Related medicine news :

1. New female sterilization technique not only quicker and easier for patients, but cheaper
2. ACE inhibitors not needed for many heart disease patients, according to new study
3. Clerks control healthcare access for uninsured patients, study finds
4. Experimental drug improves sleep in older patients, Wake Forest Baptist study shows
5. Time with patients, staff support boost flu shot rates
6. Insulin decreases inflammation, aids clot-busting drugs in heart attack patients, UB study shows
7. Diabetes management improves when patients, doctors agree on treatment goals, UMHS study finds
8. Gastric bypass surgery resolves or improves diabetes in most patients, reports Pittsburgh study
9. HIV infection may bump up risk of heart disease in younger patients, UCLA study finds
10. Web knowledge empowers patients, researcher says
11. Possible new cancer therapy shrinks tumors in melanoma patients, Science authors report

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/14/2018)... ... December 14, 2018 , ... Our competitor ... has pending lawsuits that claim its talc powder has toxic ingredients that may ... asbestos in its baby powder. The documents also show our competitor's leadership intentionally ...
(Date:12/14/2018)... Calif. (PRWEB) , ... December 14, 2018 , ... Art ... Art of Dentistry, are helping patients in La Mesa, CA interested in cosmetic dentistry ... for individuals whose teeth and gums are not aesthetically appealing because of decay, damage, ...
(Date:12/13/2018)... ... December 13, 2018 , ... Cantata Health, a leading ... outcomes, introduced new enhancements to its NetSolutions™ platform. The new features and partnerships ... technology and screen time. , Enhancements made to EHR and Financial Management ...
(Date:12/13/2018)... ... 13, 2018 , ... New research out of Roswell Park Comprehensive Cancer Center ... significantly more likely to survive than those who are sedentary, adding to the growing ... and treatment strategy. The results were published in a recent issue of the journal ...
(Date:12/13/2018)... Wis. (PRWEB) , ... December 13, 2018 , ... ... as Senior Vice President of Consultant Engagement. Beth brings over 20 years of ... team at Evergreen. Beth is passionate about building strong teams and creating vibrant ...
Breaking Medicine News(10 mins):
(Date:12/13/2018)... , ... December 14, 2018 ... ... enhance its holistic wellness experience resort-wide, The Ritz-Carlton, Amelia Island will expand ... retreats with acclaimed experts in yoga, meditation, fitness and nutrition; innovative spa ...
(Date:12/13/2018)... ... December 13, 2018 , ... As the life ... established organizations, as well as top talent, have the ability to remain agile ... , Through years of working hand-in-hand with some of the country’s top ...
(Date:12/13/2018)... WASHINGTON (PRWEB) , ... December 13, 2018 , ... ... who work closely with patients from all 50 states and 35 countries around the ... Sandy Li, M.D., to the practice. Dr. Li will see Mandarin and ...
Breaking Medicine Technology:
Cached News: