HOME >> MEDICINE >> NEWS
For leg-bypass patients, drugs can save lives and limbs, but many patients go without them

ANN ARBOR, MI The same drugs that help millions of heart patients can also aid people who have painful blockages in the blood vessels of their legs, new research from the University of Michigan Cardiovascular Center shows.

Drugs called statins and ACE inhibitors can save those patients' lives, or their limbs, if they take the medications before having a leg bypass operation, the study finds.

But the U-M researchers found that only about half of patients whose leg vessel disease has progressed far enough to require a bypass operation are actually taking the potentially beneficial drugs.

The results, published in the February issue of the Journal of Vascular Surgery, suggest that vascular surgeons should make sure their patients are receiving appropriate drugs before performing leg bypass surgery to re-route blood flow around a severely clogged leg artery.

"What we found surprised us," says lead author and U-M vascular surgeon Peter Henke, M.D. "Patients who were taking statins before their leg bypass operation had better patency, or openness, of their bypass graft, and a lower risk of leg amputation after surgery. Those taking ACE inhibitors had a lower risk of dying after the operation. And the effect of the medications far outweighed the effects of the patients' PAD severity, other medical problems, or the type of graft used."

An estimated 12 million Americans have peripheral arterial disease, or PAD, in which clogged or stiffened leg arteries cause pain during walking or rest. Left untreated, PAD can cause non-healing wounds and gangrene, and can led to amputation unless the blocked area is opened or bypassed. It's also associated with a high risk of heart attack and stroke.

The new U-M study looked at the usage rates and effects of statins and ACE inhibitors in 293 patients with advanced PAD who had open-leg bypass operations at the U-M Health System between 1997 and 2002. Average follow-up was 17 month
'"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
27-Jan-2004


Page: 1 2 3 4

Related medicine news :

1. New female sterilization technique not only quicker and easier for patients, but cheaper
2. ACE inhibitors not needed for many heart disease patients, according to new study
3. Clerks control healthcare access for uninsured patients, study finds
4. Experimental drug improves sleep in older patients, Wake Forest Baptist study shows
5. Time with patients, staff support boost flu shot rates
6. Insulin decreases inflammation, aids clot-busting drugs in heart attack patients, UB study shows
7. Diabetes management improves when patients, doctors agree on treatment goals, UMHS study finds
8. Gastric bypass surgery resolves or improves diabetes in most patients, reports Pittsburgh study
9. HIV infection may bump up risk of heart disease in younger patients, UCLA study finds
10. Web knowledge empowers patients, researcher says
11. Possible new cancer therapy shrinks tumors in melanoma patients, Science authors report

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2017)... City, UT (PRWEB) , ... April 28, 2017 , ... ... in some of their formulas. This begins with the popular ClearLungs Extra Strength formula. ... will be changing the formula in the following ways:, , ...
(Date:4/28/2017)... ... ... Getting enough sleep affects much more than energy – it also has mental and physical ... compromise motor reaction time, which can increase the risk of having a car accident. ... from the NSF to help you sleep better and feel better:, , ...
(Date:4/28/2017)... Grants Pass, OR (PRWEB) , ... April 28, ... ... Adetutu Ijose, http://www.foodsthathealdaily.com , http://www.wiredlifesolutions.com , “Computers are everywhere and ... Kleyne Hour Power of Water, Global Climate Change and Your Health on Voice ...
(Date:4/28/2017)... ... April 28, 2017 , ... The Radiology Business Management Association ... for 2017-2018. The annual board election process has been in place since the RBMA ... Thomas C. Dickerson, Ed.D., FACHE, succeeds Jim Hamilton, MHA, CMM, FRBMA, as president. Dr. ...
(Date:4/28/2017)... ... April 28, 2017 , ... Children and adolescents who enter ... than children in the general population. That’s because foster care is designed to ... challenges. While no fault of their own, youth who have experienced trauma often ...
Breaking Medicine News(10 mins):
(Date:4/26/2017)... , April 26, 2017 Phoenix Marketing Solutions ... fifteenth year of fulfilling its mission of transforming science into ... highly scrutinized, Phoenix,s innovative approach supports ... community about the latest advances in science and medicine — ... was founded in 2002 by Tracy Doyle ...
(Date:4/24/2017)... England , April 24, 2017 ... development, today announced the addition of a major ... ,Validated In-situ Plate Seeding,). The VIPS has been ... and 384 well microplates as part of the ... system offers a simple and more reliable solution ...
(Date:4/20/2017)...  Vivify Health, the pioneer and market leader of ... very significant patent for the advancement of healthcare delivery ... digital health.  This landmark patent provides the company with ... Vivify,s position as the leader in remote care.  ... company to apply consumer mobile devices, wireless biometrics, EMR ...
Breaking Medicine Technology:
Cached News: