HOME >> MEDICINE >> NEWS
Foundation funds UCSF research to test diaphragms as HIV prevention tool

The Bill & Melinda Gates Foundation has awarded $28 million to test whether the diaphragm can prevent the transmission of HIV, to UCSF's Women's Global Health Imperative (WGHI), directed by Nancy Padian, PhD. The diaphragm will be the first physical barrier tested in a randomized, controlled trial for effectiveness in preventing the sexual transmission of HIV.

"The foundation is demonstrating tremendous leadership and innovation in supporting research to examine women-controlled HIV prevention methods. Their foresight could potentially save many lives," said Padian, who is also UCSF professor of obstetrics, gynecology, and reproductive science, and director of international programs at UCSF's AIDS Research Institute (ARI). The study will enroll 4500 women at two sites in South Africa and one in Zimbabwe.

Because many people are skeptical that women would use the diaphragm, Padian first conducted an acceptability study among women in Zimbabwe, where close to a third of the population is infected with HIV.

"We asked women whose partners would not consistently use condoms if they would try using the diaphragm, even though we told them we did not know if it could prevent disease. Their enthusiasm to use a product that did not require negotiating with their male partner was overwhelming." said Padian.

Because it protects the cervix, the diaphragm holds enormous promise for preventing HIV transmission. The cervix is a "hot spot" in terms of susceptibility to HIV infection and other sexually transmitted diseases (STDs), and the majority of infections most likely occur there. The surface of the cervix is very thin and fragile whereas the vaginal walls are much thicker. The cervix also has more cells with HIV specific receptor sites than the vagina.

In addition, contractions of the uterus aspirate or draw fluids up into the upper genital track, which has also been shown to be very susceptible to HIV and STDs. Physical protection o
'"/>

Contact: Jeff Sheehy
jsheehy@psg.ucsf.edu
415-597-8165
University of California - San Francisco
28-Aug-2002


Page: 1 2

Related medicine news :

1. Can you read my mind? W.M. Keck Foundation funds innovative brain research at Carnegie Mellon
2. Top honor for head of Epilepsy Foundation
3. The Larry King Cardiac Foundation presents The Changing Face of Heart Disease on Feb. 2
4. Prentiss Foundation awards $5 million to University Hospitals
5. Endocrine Society and Hormone Foundation call for increased research
6. Foundation to honor physicians and community health initiatives around the world
7. Donald W. Reynolds Foundation awards UT Southwestern $12 million to continue Dallas Heart Study
8. NYU Child Study Center and The Bear Stearns Charitable Foundation launch outreach campaign
9. Brain Science Institute at Columbia University established by Kavli Foundation gift
10. Universit de Montral receives US$11.7 million grant from Bill & Melinda Gates Foundation
11. The NCOA and The Epilepsy Foundation launch initiative to educate about epilepsy in the elderly

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/8/2016)... Pekin, IL (PRWEB) , ... February 08, 2016 ... ... debilitating conditions that co-occur frequently. While a significant number of women and men ... PTSD, not the trauma itself, that best predicts the development of an eating ...
(Date:2/8/2016)... , ... February 08, 2016 , ... TopConsumerReviews.com recently awarded ... Mole removal products. , Moles are derived from a cluster of melanin when exposed ... the wrong places and create a lifetime of embarrassment. Historically, mole removal ...
(Date:2/7/2016)... Orion, Clarkston, Metamora, Michigan (PRWEB) , ... February ... ... to correct pelvic organ prolapse with the latest techniques and the most minimally ... risk for pelvic organ prolapse, particularly after menopause. Other risk factors include surgery ...
(Date:2/6/2016)... ... February 06, 2016 , ... US Sports Camps is proud ... . This event brings together top non-profit leaders, ultimate organizations, and coaches from around ... Valerio Iani, Bay Area Disc Program Director of Youth and Education, describes this year ...
(Date:2/5/2016)... ... February 05, 2016 , ... Love is in the ... a variety of colors, assortments and packaging. This staple for Valentine’s Day is a ... location. , For Valentine’s Day, not only are long-stem roses available, but also ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... 2016 Amgen (NASDAQ: AMGN ) will present ... Conference at 9:15 a.m. ET on Wednesday, Feb. 10, 2016, ... W. Meline , executive vice president and chief financial officer ... the presentation can be accessed from the Events Calendar on ... the webcast will also be available on Amgen,s website for ...
(Date:2/5/2016)... 2016  As people age, it is natural to ... screenings and tests that are linked with certain age ... the majority of aging individuals, hearing health is too ... 37.5 million American adults who report some trouble hearing, ... hearing health a 2016 healthy aging priority.[1] ...
(Date:2/5/2016)... DIEGO , Feb. 5, 2016 Aethlon Medical, ... Joyce , Chairman and CEO, will be presenting at Source ... New York, NY at 2:15 p.m. ET ... in an Immunotherapy Panel discussion taking place at 3:15 p.m. ... for replay approximately one hour after the conclusion of the ...
Breaking Medicine Technology:
Cached News: