Foundation funds UCSF research to test diaphragms as HIV prevention tool

The Bill & Melinda Gates Foundation has awarded $28 million to test whether the diaphragm can prevent the transmission of HIV, to UCSF's Women's Global Health Imperative (WGHI), directed by Nancy Padian, PhD. The diaphragm will be the first physical barrier tested in a randomized, controlled trial for effectiveness in preventing the sexual transmission of HIV.

"The foundation is demonstrating tremendous leadership and innovation in supporting research to examine women-controlled HIV prevention methods. Their foresight could potentially save many lives," said Padian, who is also UCSF professor of obstetrics, gynecology, and reproductive science, and director of international programs at UCSF's AIDS Research Institute (ARI). The study will enroll 4500 women at two sites in South Africa and one in Zimbabwe.

Because many people are skeptical that women would use the diaphragm, Padian first conducted an acceptability study among women in Zimbabwe, where close to a third of the population is infected with HIV.

"We asked women whose partners would not consistently use condoms if they would try using the diaphragm, even though we told them we did not know if it could prevent disease. Their enthusiasm to use a product that did not require negotiating with their male partner was overwhelming." said Padian.

Because it protects the cervix, the diaphragm holds enormous promise for preventing HIV transmission. The cervix is a "hot spot" in terms of susceptibility to HIV infection and other sexually transmitted diseases (STDs), and the majority of infections most likely occur there. The surface of the cervix is very thin and fragile whereas the vaginal walls are much thicker. The cervix also has more cells with HIV specific receptor sites than the vagina.

In addition, contractions of the uterus aspirate or draw fluids up into the upper genital track, which has also been shown to be very susceptible to HIV and STDs. Physical protection o

Contact: Jeff Sheehy
University of California - San Francisco

Page: 1 2

Related medicine news :

1. Can you read my mind? W.M. Keck Foundation funds innovative brain research at Carnegie Mellon
2. Top honor for head of Epilepsy Foundation
3. The Larry King Cardiac Foundation presents The Changing Face of Heart Disease on Feb. 2
4. Prentiss Foundation awards $5 million to University Hospitals
5. Endocrine Society and Hormone Foundation call for increased research
6. Foundation to honor physicians and community health initiatives around the world
7. Donald W. Reynolds Foundation awards UT Southwestern $12 million to continue Dallas Heart Study
8. NYU Child Study Center and The Bear Stearns Charitable Foundation launch outreach campaign
9. Brain Science Institute at Columbia University established by Kavli Foundation gift
10. Universit de Montral receives US$11.7 million grant from Bill & Melinda Gates Foundation
11. The NCOA and The Epilepsy Foundation launch initiative to educate about epilepsy in the elderly

Post Your Comments:
(Date:10/9/2015)... ... October 09, 2015 , ... ... individuals from all walks of life to save money on the high cost ... $25 per month per medication, individuals and families can receive their medications delivered ...
(Date:10/9/2015)... ... 2015 , ... Ryan Fox, the founder and CEO of ... says the latest figures on the state’s sales of legalized marijuana acknowledge that ... , Last month, according to the website AllGov.com , Colorado's Department ...
(Date:10/9/2015)... ... ... was featured on NewsWatch as part of its monthly Tech Report, which features the ... special reporter for NewsWatch, conducted the review and shared with viewers how this security ... it’s more important than ever to keep homes and dorms safe and protected. That ...
(Date:10/9/2015)... , ... October 09, 2015 , ... Dignity Health named ... General Hospital Emergency Room – Chandler–McQueen opening later this month. The new ... this year in the West Valley. , “Dr. Morro is an excellent leader ...
(Date:10/9/2015)... ... 09, 2015 , ... Yisrayl Hawkins, Pastor at The House of Yahweh in ... health care back to the beginning, literally, starting in the book of Genesis. ... if only biblical laws were being taught. The letter addresses the many types ...
Breaking Medicine News(10 mins):
(Date:10/9/2015)... , Oct. 9, 2015 Ansun BioPharma ... Disease Society of America ) regarding the compassionate use ... patient on a respirator who was co-infected with influenza ... five-day course of therapy, O 2 requirement was ... patient was able to go off the respirator on ...
(Date:10/9/2015)... ,JCA-Mauvernay Award 2015, se ha otorgado a los doctores ... Takita    --> El ,JCA-Mauvernay Award 2015, ... y Junko Takita    --> ... los doctores Yutaka Kondo y ... con sede enSuiza, presentará el ,JCA-Mauvernay Award, el 10 de octubre a los ...
(Date:10/8/2015)... ® ) in adult ... NOCT study also assessed the compliance, safety, patient ... ® ) in adult patients undergoing screening, surveillance ... the compliance, safety, patient acceptability and tolerability of ... top line results for its phase III study, ...
Breaking Medicine Technology:
Cached News: