HOME >> MEDICINE >> NEWS
Foundation funds UCSF research to test diaphragms as HIV prevention tool

The Bill & Melinda Gates Foundation has awarded $28 million to test whether the diaphragm can prevent the transmission of HIV, to UCSF's Women's Global Health Imperative (WGHI), directed by Nancy Padian, PhD. The diaphragm will be the first physical barrier tested in a randomized, controlled trial for effectiveness in preventing the sexual transmission of HIV.

"The foundation is demonstrating tremendous leadership and innovation in supporting research to examine women-controlled HIV prevention methods. Their foresight could potentially save many lives," said Padian, who is also UCSF professor of obstetrics, gynecology, and reproductive science, and director of international programs at UCSF's AIDS Research Institute (ARI). The study will enroll 4500 women at two sites in South Africa and one in Zimbabwe.

Because many people are skeptical that women would use the diaphragm, Padian first conducted an acceptability study among women in Zimbabwe, where close to a third of the population is infected with HIV.

"We asked women whose partners would not consistently use condoms if they would try using the diaphragm, even though we told them we did not know if it could prevent disease. Their enthusiasm to use a product that did not require negotiating with their male partner was overwhelming." said Padian.

Because it protects the cervix, the diaphragm holds enormous promise for preventing HIV transmission. The cervix is a "hot spot" in terms of susceptibility to HIV infection and other sexually transmitted diseases (STDs), and the majority of infections most likely occur there. The surface of the cervix is very thin and fragile whereas the vaginal walls are much thicker. The cervix also has more cells with HIV specific receptor sites than the vagina.

In addition, contractions of the uterus aspirate or draw fluids up into the upper genital track, which has also been shown to be very susceptible to HIV and STDs. Physical protection o
'"/>

Contact: Jeff Sheehy
jsheehy@psg.ucsf.edu
415-597-8165
University of California - San Francisco
28-Aug-2002


Page: 1 2

Related medicine news :

1. Can you read my mind? W.M. Keck Foundation funds innovative brain research at Carnegie Mellon
2. Top honor for head of Epilepsy Foundation
3. The Larry King Cardiac Foundation presents The Changing Face of Heart Disease on Feb. 2
4. Prentiss Foundation awards $5 million to University Hospitals
5. Endocrine Society and Hormone Foundation call for increased research
6. Foundation to honor physicians and community health initiatives around the world
7. Donald W. Reynolds Foundation awards UT Southwestern $12 million to continue Dallas Heart Study
8. NYU Child Study Center and The Bear Stearns Charitable Foundation launch outreach campaign
9. Brain Science Institute at Columbia University established by Kavli Foundation gift
10. Universit de Montral receives US$11.7 million grant from Bill & Melinda Gates Foundation
11. The NCOA and The Epilepsy Foundation launch initiative to educate about epilepsy in the elderly

Post Your Comments:
(Date:7/30/2014)... 2014) The phrase "we caught it early" is possibly ... midst of a cancer diagnosis. Combating cancer in its ... certain part of the body, gives patients the best ... colon, prostate and other forms of cancer are touted ... providers recommend cancer screenings as a precautionary measure, especially ...
(Date:7/30/2014)... Orange, NJ. July 30, 2014. A new network of ... NIH Stroke Trials Network (NIH StrokeNet) is working ... the U.S. Despite advances of the last two ... year, stroke causes death or disability for 795,000 Americans. ... aging of the population. , To accelerate the ...
(Date:7/30/2014)... July 30, 2014 The Technology Association ... Alliance of TAG (B&TA), today issued its final call ... Awards. , Interested companies have until August 29th 2014 ... Semi-Finalists will be selected by the Excalibur Judging Committee. ... meet with the judges for interviewing process. , ...
(Date:7/30/2014)... 2014 Over 630 doctors worldwide are ... the revolutionary minimally invasive treatment for gum recession. Santa ... of his peers to be the “father of microsurgery” ... recent Chao Pinhole Surgical Technique® training course at the ... the recipient of the American Academy of Periodontics (AAP) ...
(Date:7/30/2014)... York (PRWEB) July 30, 2014 As ... http://www.injurybeacon.com/power-morcellator/ ) in gynecological surgeries continues to grow, Bernstein ... voice to those calling for a ban on uterine ... Debra Valverde was diagnosed with leiomyosarcoma following a hysterectomy ... a year of her diagnosis, the aggressive cancer had ...
Breaking Medicine News(10 mins):Health News:UK psychologist creates patient tool to assist with lung cancer screening decision 2Health News:UK psychologist creates patient tool to assist with lung cancer screening decision 3Health News:Kessler funded as satellite site for NIH Stroke Trials Network 2Health News:Last Call for TAG 2014 Excalibur Awards Nominations and Applications 2Health News:Last Call for TAG 2014 Excalibur Awards Nominations and Applications 3Health News:Periodontist Dr. Dennis Shanelec Comments On The Chao Pinhole Surgical Technique® Training Course 2Health News:Power Morcellator Controversy Grows, as Bernstein Liebhard LLP Notes Another Call to Ban Uterine Morcellation 2Health News:Power Morcellator Controversy Grows, as Bernstein Liebhard LLP Notes Another Call to Ban Uterine Morcellation 3Health News:Power Morcellator Controversy Grows, as Bernstein Liebhard LLP Notes Another Call to Ban Uterine Morcellation 4
(Date:7/30/2014)... 2014  There is still time to share ... 10th Annual Institute for Supply Management ® ... Supply Management is open for submissions.  The annual ... importance of supply management by recognizing supply management ... management practices.  Entries are due August 22, 2014. ...
(Date:7/30/2014)... ANN ARBOR, Mich. , July 30, 2014 ... FY2015 first quarter (ending June 27, 2014) financial results on ... results will be released after the close of the market ... to discuss the results at 4:30 p.m. EDT on the ... Richard Kurtz (CEO and Director), Rob Risser ...
(Date:7/30/2014)... Mass., July 30, 2014  Hologic, Inc. (NASDAQ: ... third fiscal quarter ended June 28, 2014. ... Revenues increased 1.0% to $632.6 million, reflecting operational growth ... compared to the same period in the prior year. ... business segments. , Breast Health revenues grew 3.5%. ...
Breaking Medicine Technology:Institute for Supply Management, Michigan State University to recognize companies with excellent supply management practices 2Advanced Photonix to Webcast Fiscal 2015 First Quarter Earnings 2Hologic Announces Third Quarter Fiscal 2014 Operating Results 2Hologic Announces Third Quarter Fiscal 2014 Operating Results 3Hologic Announces Third Quarter Fiscal 2014 Operating Results 4Hologic Announces Third Quarter Fiscal 2014 Operating Results 5Hologic Announces Third Quarter Fiscal 2014 Operating Results 6Hologic Announces Third Quarter Fiscal 2014 Operating Results 7Hologic Announces Third Quarter Fiscal 2014 Operating Results 8Hologic Announces Third Quarter Fiscal 2014 Operating Results 9Hologic Announces Third Quarter Fiscal 2014 Operating Results 10Hologic Announces Third Quarter Fiscal 2014 Operating Results 11Hologic Announces Third Quarter Fiscal 2014 Operating Results 12Hologic Announces Third Quarter Fiscal 2014 Operating Results 13Hologic Announces Third Quarter Fiscal 2014 Operating Results 14Hologic Announces Third Quarter Fiscal 2014 Operating Results 15Hologic Announces Third Quarter Fiscal 2014 Operating Results 16Hologic Announces Third Quarter Fiscal 2014 Operating Results 17
Cached News: