HOME >> MEDICINE >> NEWS
Foundation funds UCSF research to test diaphragms as HIV prevention tool

The Bill & Melinda Gates Foundation has awarded $28 million to test whether the diaphragm can prevent the transmission of HIV, to UCSF's Women's Global Health Imperative (WGHI), directed by Nancy Padian, PhD. The diaphragm will be the first physical barrier tested in a randomized, controlled trial for effectiveness in preventing the sexual transmission of HIV.

"The foundation is demonstrating tremendous leadership and innovation in supporting research to examine women-controlled HIV prevention methods. Their foresight could potentially save many lives," said Padian, who is also UCSF professor of obstetrics, gynecology, and reproductive science, and director of international programs at UCSF's AIDS Research Institute (ARI). The study will enroll 4500 women at two sites in South Africa and one in Zimbabwe.

Because many people are skeptical that women would use the diaphragm, Padian first conducted an acceptability study among women in Zimbabwe, where close to a third of the population is infected with HIV.

"We asked women whose partners would not consistently use condoms if they would try using the diaphragm, even though we told them we did not know if it could prevent disease. Their enthusiasm to use a product that did not require negotiating with their male partner was overwhelming." said Padian.

Because it protects the cervix, the diaphragm holds enormous promise for preventing HIV transmission. The cervix is a "hot spot" in terms of susceptibility to HIV infection and other sexually transmitted diseases (STDs), and the majority of infections most likely occur there. The surface of the cervix is very thin and fragile whereas the vaginal walls are much thicker. The cervix also has more cells with HIV specific receptor sites than the vagina.

In addition, contractions of the uterus aspirate or draw fluids up into the upper genital track, which has also been shown to be very susceptible to HIV and STDs. Physical protection o
'"/>

Contact: Jeff Sheehy
jsheehy@psg.ucsf.edu
415-597-8165
University of California - San Francisco
28-Aug-2002


Page: 1 2

Related medicine news :

1. Can you read my mind? W.M. Keck Foundation funds innovative brain research at Carnegie Mellon
2. Top honor for head of Epilepsy Foundation
3. The Larry King Cardiac Foundation presents The Changing Face of Heart Disease on Feb. 2
4. Prentiss Foundation awards $5 million to University Hospitals
5. Endocrine Society and Hormone Foundation call for increased research
6. Foundation to honor physicians and community health initiatives around the world
7. Donald W. Reynolds Foundation awards UT Southwestern $12 million to continue Dallas Heart Study
8. NYU Child Study Center and The Bear Stearns Charitable Foundation launch outreach campaign
9. Brain Science Institute at Columbia University established by Kavli Foundation gift
10. Universit de Montral receives US$11.7 million grant from Bill & Melinda Gates Foundation
11. The NCOA and The Epilepsy Foundation launch initiative to educate about epilepsy in the elderly

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/25/2017)... SCOTTSDALE, Ariz. (PRWEB) , ... April 25, 2017 , ... ... the latest book of the Outlier Leadership Series, Outliers in Writing, set to publish ... and Professor of Emergency Medicine at the University of Arizona College of Medicine. He ...
(Date:4/24/2017)... , ... April 24, 2017 , ... Emmanuel College ... busy nursing professionals advance their careers. Beginning in the fall of 2017, Emmanuel’s program ... degree in as few as 16 months and for as little as $14,528. These ...
(Date:4/24/2017)... City, UT (PRWEB) , ... April 24, 2017 , ... ... efforts to encourage sustainability, innovate new strategies to reduce waste, and support renewable energy. ... remedy provider. They look to nature to find solutions for health issues, and maintain ...
(Date:4/24/2017)... ... , ... Today, Bright Pink , a national non-profit organization focusing on the prevention and ... , Bright Pink is proud to announce Katie Thiede as their new Chief Executive Officer. ... as Chairman of the Board and launched a national search to find a visionary ...
(Date:4/24/2017)... (PRWEB) , ... April 24, 2017 , ... The John ... innovative technology that allows anyone, anywhere to track their cognitive health, and share results ... check their own brain health on the museum's website. , BrainCheck founder, Dr. David ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... The Global Effective Microorganisms (EM) Market ... has covered and analysed the potential of Global Effective Microorganisms ... shares and growth factors. The report identifies and analyses the ... the global market. ... 152 Tables and Figures, 6 Major Company Profiles, spread across ...
(Date:4/19/2017)... , April 19, 2017  SARES•REGIS Group ... it is developing at Conejo Spectrum Business Park ... to Atara Biotherapeutics, Inc. , a biopharmaceutical ... and life-threatening diseases that have been underserved by ... T-cell therapies for cancer, autoimmune and infectious disease. ...
(Date:4/18/2017)... April 18, 2017  Astute Medical, Inc., developer of ... to be presented at the 2017 National Kidney Foundation ... and continues through April 22. Physicians will present data ... to assess risk for acute kidney injury (AKI) during ... (ADHF). Elevated levels of TIMP-2 and ...
Breaking Medicine Technology:
Cached News: