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Four-year data show risk of relapse is halved in Risperdal patients compared to haloperidol

months, or 466 relapse-free days, for risperidone compared to seven months, or 205 days, for haloperidol).

Side effects of risperidone reported by study participants were low. Physicians and patients are typically most concerned about extrapyramidal symptoms (abnormal movements such as muscle twitching), which can be particularly prominent in persons with recent onset of the illness. When identical doses of risperidone and haloperidol were compared in this study, there were 20 to 38 percent fewer EPS cases reported for risperidone.

Schizophrenia is a debilitating illness that has no cure and affects about one in 100 people.4 This biological brain disorder seriously impairs a person's ability to think clearly, relate to others and function properly in society.

"Schizophrenia is a devastating experience for both the person experiencing the illness and their family and friends. Since one in 10 people with schizophrenia will resort to suicide, relapse prevention in persons with newly diagnosed schizophrenia has significant implications" said Professor Robin Emsley. "It is essential, therefore, that symptoms are identified and treated early and effectively."

Risperdal, the world's most widely prescribed newer generation, 'atypical' antipsychotic, is available in more than 80 countries. Depending on the country, it is approved for a variety of conditions, including treatment of schizophrenia, behavioural and psychological disturbances in patients with dementia, acute mania associated with bipolar disorders and disruptive behaviour disorders.

In addition to traditional tablets, Risperdal is available in oral solution, fast-dissolving tablets and as a long-acting injection, Risperdal Consta, the first and only such formulation for a modern antipsychotic.


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Contact: Roseann Ward
roseann.ward@resolutecommunications.com
44-20-7357-8187
Resolute Communications
22-Sep-2003


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