HOME >> MEDICINE >> NEWS
Free radicals mediate arsenic's harmful effects

New York, NY, February 12, 2001-Arsenic, a cancer-causing metal that poisons millions of people worldwide, exerts its harmful effects by boosting the body's production of damaging chemicals called free radicals, Columbia researchers report.

The new research, published in the Feb. 13 issue of Proceedings of the National Academy of Sciences, adds to growing evidence that nutrients called antioxidants, which eliminate free radicals, may help prevent cancer and other illnesses caused by such environmental toxins as arsenic, cadmium, and asbestos. Sources of antioxidants include vitamins and micronutrients commonly found in the human diet, such as vitamin C, vitamin E, and selenium.

"Arsenic is among the top environmental contaminants on the EPA Superfund list," says Dr. Tom K. Hei, the lead author of the study. "This piece of research provides the first clear-cut evidence that an environmental carcinogen acts predominantly through a free-radical pathway." Dr. Hei is professor of radiation oncology and public health at the Center for Radiological Research at Columbia University's College of Physicians and Surgeons.

"If we understand how arsenic causes cancer, we'll have better means of prevention." Antioxidants are a leading candidate for such preventive measures, he said.

The study, which also involved P&S dermatology researchers and researchers at Albert Einstein College of Medicine and Colorado State University, showed that cells cultured in the laboratory sharply increased their free radical production within five minutes of being exposed to an arsenic compound. The compound, sodium arsenite--the main toxic form of arsenic in the environment--also boosted the rate of mutations among the cells. Mutations are a key step in cancer development. The mutation rate shot up still higher when researchers added a chemical that reduced the cells' production of natural antioxidants. This was consistent with previous research suggesting that antioxidants can p
'"/>

Contact: Carolyn Conway-Hoare
cc328@columbia.edu
212-305-3900
Columbia University Medical Center
11-Feb-2001


Page: 1 2 3

Related medicine news :

1. Antioxidant gene mutation gives free radicals free reign
2. Immediate access to antibiotics stems spread of sexually transmitted diseases
3. Immediate mammogram reading may decrease stress associated with abnormal results
4. Lowering blood pressure immediately after stroke can be harmful
5. Immediate treatment helps delay progression of glaucoma
6. Angioplasty or medical therapy immediately after heart attack?
7. Immediate cholesterol drop after heart attack guards against stroke
8. Fever immediately after heart bypass surgery associated with cognitive decline
9. Two self-fulfilling prophecies are stronger, and more harmful, than one
10. Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients
11. Panel finds that scare tactics for violence prevention are harmful

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... services for healthcare compliance program management, will showcase a range of technology and ... for Assisted Living (NCAL) Convention and Expo to be held October 14–18, 2017 ...
(Date:10/12/2017)... ... 12, 2017 , ... The company has developed a suite ... regulatory authorities worldwide. From Children’s to Adults 50+, every formula has been developed ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally ... care, have expanded their existing home health joint venture through an agreement, effective ... operating a joint venture home health company with Asante, delivering clinically integrated care, ...
(Date:10/12/2017)... ... 12, 2017 , ... HMP , a leader in healthcare events and ... Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie ... annual award competition recognizes editorial and design excellence across a range of sectors. This ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... -- According to the Centers for Disease Control and Prevention (CDC), influenza ... Care is helping communities across Massachusetts , ... no-cost* flu shots through the end of the month. *Some ... ... flu shot is by the end of October, according to the Centers ...
(Date:10/2/2017)... announces the European launch of their new low volume, high throughput ... Cambridge, U.K on October 4th. The new ... unprecedented speed and sensitivity while using far less sample volume through ... ... ...
(Date:9/27/2017)... , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), a leading global ... that its MyDario product is expected to appear on The Dr. Oz ... Dr. Oz Show airs in your area: http://www.doctoroz.com/page/where-watch-dr-oz-show ... The nine-time Emmy award-winning, The Dr. Oz Show kicked ... The segment features ...
Breaking Medicine Technology:
Cached News: