HOME >> MEDICINE >> NEWS
Free radicals mediate arsenic's harmful effects

New York, NY, February 12, 2001-Arsenic, a cancer-causing metal that poisons millions of people worldwide, exerts its harmful effects by boosting the body's production of damaging chemicals called free radicals, Columbia researchers report.

The new research, published in the Feb. 13 issue of Proceedings of the National Academy of Sciences, adds to growing evidence that nutrients called antioxidants, which eliminate free radicals, may help prevent cancer and other illnesses caused by such environmental toxins as arsenic, cadmium, and asbestos. Sources of antioxidants include vitamins and micronutrients commonly found in the human diet, such as vitamin C, vitamin E, and selenium.

"Arsenic is among the top environmental contaminants on the EPA Superfund list," says Dr. Tom K. Hei, the lead author of the study. "This piece of research provides the first clear-cut evidence that an environmental carcinogen acts predominantly through a free-radical pathway." Dr. Hei is professor of radiation oncology and public health at the Center for Radiological Research at Columbia University's College of Physicians and Surgeons.

"If we understand how arsenic causes cancer, we'll have better means of prevention." Antioxidants are a leading candidate for such preventive measures, he said.

The study, which also involved P&S dermatology researchers and researchers at Albert Einstein College of Medicine and Colorado State University, showed that cells cultured in the laboratory sharply increased their free radical production within five minutes of being exposed to an arsenic compound. The compound, sodium arsenite--the main toxic form of arsenic in the environment--also boosted the rate of mutations among the cells. Mutations are a key step in cancer development. The mutation rate shot up still higher when researchers added a chemical that reduced the cells' production of natural antioxidants. This was consistent with previous research suggesting that antioxidants can p
'"/>

Contact: Carolyn Conway-Hoare
cc328@columbia.edu
212-305-3900
Columbia University Medical Center
11-Feb-2001


Page: 1 2 3

Related medicine news :

1. Antioxidant gene mutation gives free radicals free reign
2. Immediate access to antibiotics stems spread of sexually transmitted diseases
3. Immediate mammogram reading may decrease stress associated with abnormal results
4. Lowering blood pressure immediately after stroke can be harmful
5. Immediate treatment helps delay progression of glaucoma
6. Angioplasty or medical therapy immediately after heart attack?
7. Immediate cholesterol drop after heart attack guards against stroke
8. Fever immediately after heart bypass surgery associated with cognitive decline
9. Two self-fulfilling prophecies are stronger, and more harmful, than one
10. Blood transplants may be more harmful than bone marrow transplants in pediatric leukemia patients
11. Panel finds that scare tactics for violence prevention are harmful

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Free radicals mediate arsenic harmful effects

(Date:12/17/2014)... HeartMath® Inc., recognized as one of the ... (HRV), heart coherence and the physiology of emotions, ... algorithms to chipset manufacturers and consumer electronics companies. ... offer its HRV solutions, tap into its HRV ... normative HRV databases and algorithms for developing consumer ...
(Date:12/17/2014)... Appleton, WI (PRWEB) December 17, 2014 ... Benefit Administrators and its Argus Claim Review division ... two of the most common ways savings are achieved ... administrator (TPA) attributes millions of dollars in savings to ... saved in 2013. , As explained by Tom Doney, ...
(Date:12/17/2014)... IL (PRWEB) December 17, 2014 Now ... Awards celebrate the best of the best in senior ... award is only given to communities and agencies that ... the SeniorAdvisor.com site. Of the nearly 100,000 providers currently ... award. Winners of the SeniorAdvisor.com Best of 2015 Awards ...
(Date:12/17/2014)... gas prices rose in recent years, so did motorcyclist ... times of gas increases, more people start using motorcycles ... explained. They examined data gathered between 2002 and ... motorcycle registrations in the United States and the third ... a strong association between rising gas prices and an ...
(Date:12/17/2014)... News) -- Expectant parents should leave prenatal picture-taking to ... Use of ultrasound imaging and heartbeat monitors to ... the agency warns. "Although there is a ... imaging and heartbeat monitors, prudent use of these devices ... an FDA biomedical engineer, said in an agency news ...
Breaking Medicine News(10 mins):Health News:HeartMath® Inc.’s HRV Platform Solutions Available for Licensing 2Health News:HeartMath® Inc.’s HRV Platform Solutions Available for Licensing 3Health News:Out-of-Network & Medical Necessity Reviews among Top Ways TPA Identifies Significant Medical Claim Savings 2Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 2Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 3Health News:When Gas Prices Go Up, So Do Motorcycle Accidents, Study Finds 2Health News:FDA Warns Against Fetal 'Keepsake' Videos 2
(Date:12/19/2014)... Research and Markets ( http://www.researchandmarkets.com/research/942kh3/micro_market ... "Micro Market Monitor: North American Dermatology Diagnostic Devices ... http://photos.prnewswire.com/prnh/20130307/600769 Cosmetic ... has resulted in fueling the overall demand of ... of these dermatology devices is to assist in ...
(Date:12/19/2014)... Calif., Dec. 18, 2014 Capnia, Inc. ... development of medical diagnostics based on its proprietary ... flow, today announced financial results for the third ... "Following the completion of our initial ... to maximize the recently initiated CoSense® commercial launch," ...
(Date:12/19/2014)... 2014 Since last month,s FBI shutdown of ... as the leading online black market for illegal drugs ... its offering of drugs and other illegal items.  New ... did succeed in lowering the numbers of drugs and ... markets in August. But some new sites that have ...
Breaking Medicine Technology:Micro Market Monitor: North American Dermatology Diagnostic Devices Market 2Micro Market Monitor: North American Dermatology Diagnostic Devices Market 3Capnia Reports Third Quarter 2014 Financial Results 2Capnia Reports Third Quarter 2014 Financial Results 3Capnia Reports Third Quarter 2014 Financial Results 4Capnia Reports Third Quarter 2014 Financial Results 5Capnia Reports Third Quarter 2014 Financial Results 6Capnia Reports Third Quarter 2014 Financial Results 7Capnia Reports Third Quarter 2014 Financial Results 8Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 2Post Silk Road - Another Online Drug Den Now Dominates the DarkNet 3
Cached News: