HOME >> MEDICINE >> NEWS
From diagnostic tool to cancer therapy

Cancer patients could be benefiting more than they realise from diagnostic scans. Research published today in Breast Cancer Research suggests that a radioactive molecule widely used to evaluate advanced tumours can kill cancer cells.

Dr. Ekaterina Dadachova and her team from the Albert Einstein College of Medicine of Yeshiva University, USA, examined how radioactive glucose affects breast tumours in mice. They found that, injected at certain doses, the radiation from the glucose killed cancer cells without being toxic to other tissues.

Glucose that is tagged with radioactive fluorine-18 is commonly used in PET imaging (positron emission tomography imaging) to examine the size and progression of a known tumour. The method exploits the way in which normal glucose is metabolised by the body. When a patient is injected with radioactive glucose, the cells of the body try to use it as they would normal glucose. However, the fluorine prevents the radioactive glucose from being completely metabolised. Instead the glucose is trapped inside the cells. The patient is then scanned and doctors can see where the radioactive substance has been stored by analysing the pattern of energy it emits. Cancerous tissue, which uses more glucose than normal tissue, absorbs more radioactivity and appears brighter on the PET images.

Dr. Dadachova and colleagues suggest that: "Metabolic trapping of fluorine-18 labelled glucose is an attractive mechanism to deliver radioactivity to tumours as cancer cells have enhanced rates of glucose utilisation." The treatment would be relatively well tolerated by the body because the greatest amount of radioactivity is delivered straight to the tumour cells with relatively little of it affecting healthy tissues.

The tissue most sensitive to radiation is the bone marrow. If it is damaged, the patient can develop leukaemia. The maximum amount of radiation acceptable damages less than 5% of the marrow over 5 years. Even t
'"/>

Contact: Gemma Bradley
press@biomedcentral.com
44-0-20-7323- 0323
BioMed Central
21-Aug-2003


Page: 1 2

Related medicine news :

1. Mailman School of Public Health researchers develop infectious disease diagnostic tool
2. Nanoscale diagnostic sets sights on Alzheimers
3. Capsule endoscopy aids in detection of small bowel tumors inaccessible to other diagnostic tests
4. New system translates improved diagnostic information to target radiation at tumors
5. Promising diagnostic test for sleeping sickness
6. UK study quantifies cancer risk from diagnostic X-rays
7. Many diagnostic tests are not based on good evidence
8. UT Southwestern, Childrens Medical Center to test new rapid diagnostic equipment
9. SNM collaboration yields diagnostic nuclear medicine guide for compliance with NRC regulations
10. Novel diagnostic tool detects life-threatening infections faster than standard nuclear imaging tests
11. Electrodiagnostic studies the better alternative for diagnosing carpal tunnel syndrome

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/30/2017)... ... April 30, 2017 , ... PracticeMatch, a company that provides healthcare recruiting resources ... year’s physician career fairs, with this year’s RSVPs and registrations so far tracking a ... year of national physician career fairs is located on the PracticeMatch website. ...
(Date:4/29/2017)... , ... April 29, 2017 , ... TransDark is a ... from one video to the next without having to set a single keyframe in ... transitions to enhance your video production. , TransDark features dynamic transitions that momentarily splits ...
(Date:4/29/2017)... ... 2017 , ... Saturday, April 29, marks World Veterinary Day, ... on animal health and welfare as well as on public health. The World ... theme each year and this year have selected “Antimicrobial Resistance—From Awareness to Action,” ...
(Date:4/28/2017)... NY (PRWEB) , ... April 28, 2017 , ... It's ... there are a number of illnesses that are unclear as to whether or not ... their heads. Bronchitis is one of these illnesses. So, FindaTopDoc took a look into ...
(Date:4/28/2017)... LINCOLN, R.I. (PRWEB) , ... April 28, 2017 , ... Getting enough sleep affects much ... Sleep Foundation (NSF), going just 19 hours without sleep can compromise motor reaction time, which ... Awareness Week, and Amica Insurance is sharing the following tips from the NSF to help ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)...   ZappRx, Inc ., a digital health company focused ... announced it closed $25 million in Series B funding led ... in Seattle that is part of ... Series B round included participation from SR One , ... GV (formerly Google Ventures). As part of the financing, ...
(Date:4/20/2017)... DUBLIN , April 20, 2017 ... "Global Pharmacogenomics Market Size, Market Share, Application Analysis, Regional Outlook, ... 2024" report to their offering. ... The global pharmacogenomics market was valued at US$ ... 11,938.8 Mn by 2024, expanding at a CAGR of 5.6% ...
(Date:4/20/2017)... , April 20, 2017 NeuroVive Pharmaceutical ... today announced positive preclinical results demonstrating anti-fibrotic ... for non-alcoholic steatohepatitis (NASH), in an additional ... NV556 has previously shown similar anti-fibrotic ... Today, NeuroVive,s scientists present novel data demonstrating ...
Breaking Medicine Technology:
Cached News: