HOME >> MEDICINE >> NEWS
From diagnostic tool to cancer therapy

Cancer patients could be benefiting more than they realise from diagnostic scans. Research published today in Breast Cancer Research suggests that a radioactive molecule widely used to evaluate advanced tumours can kill cancer cells.

Dr. Ekaterina Dadachova and her team from the Albert Einstein College of Medicine of Yeshiva University, USA, examined how radioactive glucose affects breast tumours in mice. They found that, injected at certain doses, the radiation from the glucose killed cancer cells without being toxic to other tissues.

Glucose that is tagged with radioactive fluorine-18 is commonly used in PET imaging (positron emission tomography imaging) to examine the size and progression of a known tumour. The method exploits the way in which normal glucose is metabolised by the body. When a patient is injected with radioactive glucose, the cells of the body try to use it as they would normal glucose. However, the fluorine prevents the radioactive glucose from being completely metabolised. Instead the glucose is trapped inside the cells. The patient is then scanned and doctors can see where the radioactive substance has been stored by analysing the pattern of energy it emits. Cancerous tissue, which uses more glucose than normal tissue, absorbs more radioactivity and appears brighter on the PET images.

Dr. Dadachova and colleagues suggest that: "Metabolic trapping of fluorine-18 labelled glucose is an attractive mechanism to deliver radioactivity to tumours as cancer cells have enhanced rates of glucose utilisation." The treatment would be relatively well tolerated by the body because the greatest amount of radioactivity is delivered straight to the tumour cells with relatively little of it affecting healthy tissues.

The tissue most sensitive to radiation is the bone marrow. If it is damaged, the patient can develop leukaemia. The maximum amount of radiation acceptable damages less than 5% of the marrow over 5 years. Even t
'"/>

Contact: Gemma Bradley
press@biomedcentral.com
44-0-20-7323- 0323
BioMed Central
21-Aug-2003


Page: 1 2

Related medicine news :

1. Mailman School of Public Health researchers develop infectious disease diagnostic tool
2. Nanoscale diagnostic sets sights on Alzheimers
3. Capsule endoscopy aids in detection of small bowel tumors inaccessible to other diagnostic tests
4. New system translates improved diagnostic information to target radiation at tumors
5. Promising diagnostic test for sleeping sickness
6. UK study quantifies cancer risk from diagnostic X-rays
7. Many diagnostic tests are not based on good evidence
8. UT Southwestern, Childrens Medical Center to test new rapid diagnostic equipment
9. SNM collaboration yields diagnostic nuclear medicine guide for compliance with NRC regulations
10. Novel diagnostic tool detects life-threatening infections faster than standard nuclear imaging tests
11. Electrodiagnostic studies the better alternative for diagnosing carpal tunnel syndrome

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: From diagnostic tool cancer therapy

(Date:12/17/2014)... Crest Hill, IL (PRWEB) December 17, 2014 ... of 2015 Awards celebrate the best of the best ... States. The award is only given to communities and ... families through the SeniorAdvisor.com site. Of the nearly 100,000 ... with this award. Winners of the SeniorAdvisor.com Best of ...
(Date:12/17/2014)... TUESDAY, Dec. 16, 2014 (HealthDay News) -- Poor students get ... home, a new study finds. But, the opposite is ... that having fruits and vegetables at school may give a ... But, no matter what the family income level, students ... school, the study found. The study was published recently ...
(Date:12/15/2014)... (PRWEB) December 15, 2014 A recent ... United States women as impacting skin health and beauty ... C’s of skin care.” Water and health advocate and ... a recent article describing the survey and the Four ... item in every category discussed would benefit from paying ...
(Date:12/15/2014)... SIMpalm, a leading mobile app development ... for its client, which allows users to keep track ... in finding the right wine. At the center ... sensory, chemistry and wine information. All this information is ... Those wines that are close counterparts to one another ...
(Date:12/15/2014)... 2014 The increase in prevalence of disabling ... main factors which is contributing to the growth in the ... and treatment of hearing loss and balance disorders are known ... - microphone, speaker and amplifier. The global market is expected ... during the period from 2014 to 2019. Some of the ...
Breaking Medicine News(10 mins):Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 2Health News:The Inn at Willow Falls - Crest Hill, IL Wins 2015 Best of Assisted Living Award from SeniorAdvisor.com 3Health News:Poor Students Eat Healthier Foods at School, Study Finds 2Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 2Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 3Health News:Use WinMatch Connect App to Keep Track of Wines You Like 2Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 2Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 3Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 4
(Date:12/15/2014)... 12, 2014 Research and Markets ... http://www.researchandmarkets.com/research/ms3j8c/cardiac ) has announced the addition of the ...  report to their offering. Global Guidewires sector is ... North America accounts for nearly 35% ... claims approximately 25% (2018). Asia-Pacific ...
(Date:12/15/2014)... Dec. 15, 2014  Colorado and Washington State ... adult use of cannabis. Oregon , ... ended prohibition during the November 2014 elections. ... http://photos.prnewswire.com/prnh/20141212/164153LOGO The benefits of legalizing ... obvious benefits like the increased tax revenue for state and ...
(Date:12/15/2014)... Colo. , Dec. 15, 2014  The Government of ... collaboration of AABB, Global Blood Fund (GBF) and Terumo BCT to ... , as well as provide long-term health system capacity to ... Facts: , The Ghanaian Ebola Readiness and Resilience Initiative ... Ghana,s preparations for the possible arrival of the ...
Breaking Medicine Technology:Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 4CannaInsider.com Estimates 200,000 New Jobs in the Cannabis Industry by 2015 2Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 2Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 3Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 4Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 5Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 6
Cached News: