HOME >> MEDICINE >> NEWS
From diagnostic tool to cancer therapy

Cancer patients could be benefiting more than they realise from diagnostic scans. Research published today in Breast Cancer Research suggests that a radioactive molecule widely used to evaluate advanced tumours can kill cancer cells.

Dr. Ekaterina Dadachova and her team from the Albert Einstein College of Medicine of Yeshiva University, USA, examined how radioactive glucose affects breast tumours in mice. They found that, injected at certain doses, the radiation from the glucose killed cancer cells without being toxic to other tissues.

Glucose that is tagged with radioactive fluorine-18 is commonly used in PET imaging (positron emission tomography imaging) to examine the size and progression of a known tumour. The method exploits the way in which normal glucose is metabolised by the body. When a patient is injected with radioactive glucose, the cells of the body try to use it as they would normal glucose. However, the fluorine prevents the radioactive glucose from being completely metabolised. Instead the glucose is trapped inside the cells. The patient is then scanned and doctors can see where the radioactive substance has been stored by analysing the pattern of energy it emits. Cancerous tissue, which uses more glucose than normal tissue, absorbs more radioactivity and appears brighter on the PET images.

Dr. Dadachova and colleagues suggest that: "Metabolic trapping of fluorine-18 labelled glucose is an attractive mechanism to deliver radioactivity to tumours as cancer cells have enhanced rates of glucose utilisation." The treatment would be relatively well tolerated by the body because the greatest amount of radioactivity is delivered straight to the tumour cells with relatively little of it affecting healthy tissues.

The tissue most sensitive to radiation is the bone marrow. If it is damaged, the patient can develop leukaemia. The maximum amount of radiation acceptable damages less than 5% of the marrow over 5 years. Even t
'"/>

Contact: Gemma Bradley
press@biomedcentral.com
44-0-20-7323- 0323
BioMed Central
21-Aug-2003


Page: 1 2

Related medicine news :

1. Mailman School of Public Health researchers develop infectious disease diagnostic tool
2. Nanoscale diagnostic sets sights on Alzheimers
3. Capsule endoscopy aids in detection of small bowel tumors inaccessible to other diagnostic tests
4. New system translates improved diagnostic information to target radiation at tumors
5. Promising diagnostic test for sleeping sickness
6. UK study quantifies cancer risk from diagnostic X-rays
7. Many diagnostic tests are not based on good evidence
8. UT Southwestern, Childrens Medical Center to test new rapid diagnostic equipment
9. SNM collaboration yields diagnostic nuclear medicine guide for compliance with NRC regulations
10. Novel diagnostic tool detects life-threatening infections faster than standard nuclear imaging tests
11. Electrodiagnostic studies the better alternative for diagnosing carpal tunnel syndrome

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: From diagnostic tool cancer therapy

(Date:3/26/2015)... (PRWEB) March 26, 2015 Innovative ... brain aneurysms and preventing often fatal ruptures, says ... dedicated to raising awareness of brain aneurysms and ... issue has captured national attention with the ... 49, who died last Friday after suffering a ...
(Date:3/26/2015)... The Pulmonary Hypertension Association ... Treatments Act (PATA) that was introduced in the ... B. McKinley (R-WV) and Lois Capps (D-CA). This ... medications placed in a specialty tier and make ... expenses. , This legislation is critical to individuals ...
(Date:3/26/2015)... In preparation for the 2016 United ... by Samir Becic, has issued “report cards” for ... and fitness, as well as their promotion of health ... Sen. Ted Cruz, who has officially announced his candidacy ... politicians who have shown interest in running for office. ...
(Date:3/26/2015)... March 26, 2015 Los Lunas, N.M., ... pageant. Not until last year, when she attended a ... pulmonary hypertension (PH) – a debilitating disease of the ... can lead to right-heart failure. The disease turned the ... 2003. Lyndsi entered the pageant to raise awareness about ...
(Date:3/26/2015)... 2015 DiabetesSisters is pleased to announce ... of $25,000 for a groundbreaking project in the field ... a partnering organization, The Society for Women’ Health Research, ... on women and diabetes. The “Women & Diabetes: 10Q ... research to improve the health and wellbeing of women ...
Breaking Medicine News(10 mins):Health News:Research and Funding Are Keys to Raising Awareness and Ultimately Preventing Fatal Brain Aneurysm Ruptures 2Health News:Research and Funding Are Keys to Raising Awareness and Ultimately Preventing Fatal Brain Aneurysm Ruptures 3Health News:Pulmonary Hypertension Association Part of Coalition Supporting the Patients’ Access to Treatments Act 2Health News:How the Candidates for the 2016 Presidential Election Rank in Health and Fitness 2Health News:How the Candidates for the 2016 Presidential Election Rank in Health and Fitness 3Health News:Albuquerque Area Mom Enters Mrs. New Mexico Pageant to Help Fight Pulmonary Hypertension 2Health News:DiabetesSisters Receives Financial Support for Landmark Report from Janssen Pharmaceuticals 2
(Date:3/26/2015)... März 2015  Die National Association of ... 2015 an Zulassungsanträge für Domainnamen mit der ... Seit dem Start des .Pharmacy Top-Level Domain- ... .pharmacy-Domainnamen zugelassen, die für die vorherigen, begrenzten ... Die NABP startete .pharmacy TLD, um Verbrauchern ...
(Date:3/26/2015)... Mass. , March 26, 2015 /PRNewswire/ ... announced that it will present preclinical and ... at the 2015 American Association for Cancer ... 18-22, 2015 at the Pennsylvania Convention Center in Philadelphia. The presentations ... engineering and nanoliposomal technology platforms, as well ...
(Date:3/26/2015)... , March 26, 2015 ... on the development of first-in-class products to induce ... that it closed an equity financing of shares ... approximately $22 million, including the conversion of approximately ... from the financing will be used to support ...
Breaking Medicine Technology:Alle abgebenden Apotheken berechtigt, um ab dem 1. April 2015 .Pharmacy-Domainnamen zu beantragen 2Merrimack to Highlight Extensive Oncology Pipeline at the 2015 American Association for Cancer Research Annual Meeting 2Merrimack to Highlight Extensive Oncology Pipeline at the 2015 American Association for Cancer Research Annual Meeting 3Gelesis Closes $22M Equity Financing 2Gelesis Closes $22M Equity Financing 3
Cached News: