HOME >> MEDICINE >> NEWS
From diagnostic tool to cancer therapy

Cancer patients could be benefiting more than they realise from diagnostic scans. Research published today in Breast Cancer Research suggests that a radioactive molecule widely used to evaluate advanced tumours can kill cancer cells.

Dr. Ekaterina Dadachova and her team from the Albert Einstein College of Medicine of Yeshiva University, USA, examined how radioactive glucose affects breast tumours in mice. They found that, injected at certain doses, the radiation from the glucose killed cancer cells without being toxic to other tissues.

Glucose that is tagged with radioactive fluorine-18 is commonly used in PET imaging (positron emission tomography imaging) to examine the size and progression of a known tumour. The method exploits the way in which normal glucose is metabolised by the body. When a patient is injected with radioactive glucose, the cells of the body try to use it as they would normal glucose. However, the fluorine prevents the radioactive glucose from being completely metabolised. Instead the glucose is trapped inside the cells. The patient is then scanned and doctors can see where the radioactive substance has been stored by analysing the pattern of energy it emits. Cancerous tissue, which uses more glucose than normal tissue, absorbs more radioactivity and appears brighter on the PET images.

Dr. Dadachova and colleagues suggest that: "Metabolic trapping of fluorine-18 labelled glucose is an attractive mechanism to deliver radioactivity to tumours as cancer cells have enhanced rates of glucose utilisation." The treatment would be relatively well tolerated by the body because the greatest amount of radioactivity is delivered straight to the tumour cells with relatively little of it affecting healthy tissues.

The tissue most sensitive to radiation is the bone marrow. If it is damaged, the patient can develop leukaemia. The maximum amount of radiation acceptable damages less than 5% of the marrow over 5 years. Even t
'"/>

Contact: Gemma Bradley
press@biomedcentral.com
44-0-20-7323- 0323
BioMed Central
21-Aug-2003


Page: 1 2

Related medicine news :

1. Mailman School of Public Health researchers develop infectious disease diagnostic tool
2. Nanoscale diagnostic sets sights on Alzheimers
3. Capsule endoscopy aids in detection of small bowel tumors inaccessible to other diagnostic tests
4. New system translates improved diagnostic information to target radiation at tumors
5. Promising diagnostic test for sleeping sickness
6. UK study quantifies cancer risk from diagnostic X-rays
7. Many diagnostic tests are not based on good evidence
8. UT Southwestern, Childrens Medical Center to test new rapid diagnostic equipment
9. SNM collaboration yields diagnostic nuclear medicine guide for compliance with NRC regulations
10. Novel diagnostic tool detects life-threatening infections faster than standard nuclear imaging tests
11. Electrodiagnostic studies the better alternative for diagnosing carpal tunnel syndrome

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/27/2016)... ... 2016 , ... Beleza Medspa has initiated a new program to ... the first time that Coolsculpting is being used for for more than just cosmetic ... they meet the prescribed body-fat standard, measured by the circumference-based tape method. The ...
(Date:5/27/2016)... ... May 27, 2016 , ... ... to students studying complementary medicine. Allison Outerbridge is this year’s Life University ... on May 18 at the university’s Student Leadership Awards ceremony. , Outerbridge is ...
(Date:5/26/2016)... ... , ... There are many ways to cook a hot dog, but new ... prefer their dogs straight off the grill. Of the 90 percent of Americans who ... cook a hot dog, far outpacing other cooking methods such as steaming (12 percent), ...
(Date:5/26/2016)... ... May 26, 2016 , ... Intalere, the ... and suppliers for its inaugural Member Conference at the Paris Hotel in Las ... the operational health of America’s healthcare providers. , The conference was highlighted by ...
(Date:5/26/2016)... ... May 26, 2016 , ... On Memorial Day, Hope For Heroes ... lives in military battle for the country. The nonprofit Hope For Heroes partnered ... programs that empower independence for disabled military veterans, as well as police, firemen, and ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... 25, 2016 Inivata, a ... of circulating tumour DNA (ctDNA) analysis to improve ... of Professor Clive Morris as Chief ... the clinical development programme, scientific collaborations, and through ... significant improvements in clinical outcomes for patients. ...
(Date:5/24/2016)...   , Study met ... bowel cleansing and superiority in , ... of the ascending colon   ... Norgine B.V. today announced new positive data from the phase ... preparation) versus standard 2 litre PEG with ascorbate. The study met ...
(Date:5/24/2016)... has joined VMS BioMarketing as senior vice president of sales, announced Andrea Heslin ... will lead the company,s business development and sales team, exploring new opportunities for VMS ... http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
Breaking Medicine Technology:
Cached News: