HOME >> MEDICINE >> NEWS
From diagnostic tool to cancer therapy

Cancer patients could be benefiting more than they realise from diagnostic scans. Research published today in Breast Cancer Research suggests that a radioactive molecule widely used to evaluate advanced tumours can kill cancer cells.

Dr. Ekaterina Dadachova and her team from the Albert Einstein College of Medicine of Yeshiva University, USA, examined how radioactive glucose affects breast tumours in mice. They found that, injected at certain doses, the radiation from the glucose killed cancer cells without being toxic to other tissues.

Glucose that is tagged with radioactive fluorine-18 is commonly used in PET imaging (positron emission tomography imaging) to examine the size and progression of a known tumour. The method exploits the way in which normal glucose is metabolised by the body. When a patient is injected with radioactive glucose, the cells of the body try to use it as they would normal glucose. However, the fluorine prevents the radioactive glucose from being completely metabolised. Instead the glucose is trapped inside the cells. The patient is then scanned and doctors can see where the radioactive substance has been stored by analysing the pattern of energy it emits. Cancerous tissue, which uses more glucose than normal tissue, absorbs more radioactivity and appears brighter on the PET images.

Dr. Dadachova and colleagues suggest that: "Metabolic trapping of fluorine-18 labelled glucose is an attractive mechanism to deliver radioactivity to tumours as cancer cells have enhanced rates of glucose utilisation." The treatment would be relatively well tolerated by the body because the greatest amount of radioactivity is delivered straight to the tumour cells with relatively little of it affecting healthy tissues.

The tissue most sensitive to radiation is the bone marrow. If it is damaged, the patient can develop leukaemia. The maximum amount of radiation acceptable damages less than 5% of the marrow over 5 years. Even t
'"/>

Contact: Gemma Bradley
press@biomedcentral.com
44-0-20-7323- 0323
BioMed Central
21-Aug-2003


Page: 1 2

Related medicine news :

1. Mailman School of Public Health researchers develop infectious disease diagnostic tool
2. Nanoscale diagnostic sets sights on Alzheimers
3. Capsule endoscopy aids in detection of small bowel tumors inaccessible to other diagnostic tests
4. New system translates improved diagnostic information to target radiation at tumors
5. Promising diagnostic test for sleeping sickness
6. UK study quantifies cancer risk from diagnostic X-rays
7. Many diagnostic tests are not based on good evidence
8. UT Southwestern, Childrens Medical Center to test new rapid diagnostic equipment
9. SNM collaboration yields diagnostic nuclear medicine guide for compliance with NRC regulations
10. Novel diagnostic tool detects life-threatening infections faster than standard nuclear imaging tests
11. Electrodiagnostic studies the better alternative for diagnosing carpal tunnel syndrome

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2017)... ... 24, 2017 , ... Viewers who like to educate themselves on current issues ... goods, services, and societal issues tend to appreciate and love the "Informed" series, hosted ... utilizing running events for causes around the world. , Running for charity ...
(Date:3/24/2017)... ... March 24, 2017 , ... Judy Buchanan, co-owner ... in Frederick, MD. Judy says, “I am passionate about sharing Reiki as a ... very difficult and challenging time.” , A Certified Medical Reiki™ Master trained by ...
(Date:3/24/2017)... , ... March 24, 2017 , ... “Vintage and Harvest ... retired minister and college Bible teacher residing in North Carolina with his wife, Anna ... have blessed them with six grandchildren. David is also the author of “Shadow and ...
(Date:3/23/2017)... WA (PRWEB) , ... March 23, 2017 , ... In ... and now estimates that there could be four million Zika-related cases in the Americas ... date with numbers of US cases reported per year skyrocketing to an estimated 329,000. ...
(Date:3/23/2017)... , ... March 23, 2017 , ... ... services to their communities, 16 more public health departments have been awarded national ... bring another 4.5 million people into the expanding network of communities across the ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... Norway , Mar 24, 2017 The ... approved the company,s Annual Report 2016 including the complete 2016 ... announcement and available on Nordic Nanovector,s website in the section ... ... IR enquiries: Tone Kvåle, Chief Financial Officer Cell: +47-91-51-95-76 ...
(Date:3/23/2017)... The key factors driving the growth ... accelerating economic growth and increasing healthcare expenditure. Some of the ... expectancy of ESRD patients, rising demand for home PD treatment ... of the market is hindered by high treatment costs and ... ...
(Date:3/23/2017)... LONDON , March 23, 2017 ... comprehensive research report created through extensive primary research ... research, the report aims to present the analysis ... basis of Procedure (Replacement and Repair); Replacement Procedure ... (TAVR)), Repair By Technique (Surgical Devices, Balloon Valvuloplasty, ...
Breaking Medicine Technology:
Cached News: