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GI health affected by consumption of coffee and carbonated drinks

serum alanine aminotransferase (ALT) activity and was seen in approximately 8.7 percent of this high-risk population. In analyses both unadjusted and adjusted for age, sex, ethnicity and cigarette smoking, the prevalence of liver injury declined with increasing coffee drinking and caffeine consumption, though the protective effect was greater for caffeine intake. The correlation was consistent across subgroups when defined by individual risk factors for liver injury, as well as when applied to persons without impaired liver function. "There is surprisingly little evidence-based information on the influence of diet and nutrition on the course and severity of chronic liver disease," said James Everhart, M.D., M.P.H., co- author of the study. "These results warrant further study."

Rise of Esophageal Adenocarcinoma in USA is Temporally Associated with the Rise in Carbonated Soft Drink Consumption (Abstract 105860*)
Researchers at Tata Memorial Hospital in India have found a strong correlation between the rise in per capita consumption of carbonated soft drinks (CSD) in the past 20 years and the increasing rates of esophageal cancer (ACE) in the United States.

Based on available data on diet changes in America from the U.S. Department of Agriculture, per capita consumption of CSD rose by more than 450 percent during the past half-century, from 10.8 gallons in 1946 to 49.2 gallons in 2000. At the same time, in the last 25 years, incidence rates of ACE have risen by more than 570 percent in American white males and continue to increase. The rise in CSD consumption preceded the rise in cases of ACE by 20 years. A 40 percent increase for each five-year increase in date of birth - a birth cohort effect - was previously reported. Using linear regression to compare trends between CSD and ACE rates, the researchers found a highly significant correlation between the two (r=0.99, 95% CI 0.96-1.0).

Researchers found published dat
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17-May-2004


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