HOME >> MEDICINE >> NEWS
Garlic supplements can impede HIV medication

Researchers have found garlic supplements can cause a potentially harmful side effect when combined with a type of medication used to treat HIV/AIDS. Investigators from the National Institutes of Health (NIH) observed that garlic supplements sharply reduced blood levels of the anti-HIV drug saquinavir. The study results appear this week in an on-line edition of Clinical Infectious Diseases (http://www.journals.uchicago.edu/CID/journal/home.html).

In the presence of garlic supplements, blood concentrations of saquinavir decreased by about 50 percent among our study participants, explains the studys senior co-author Judith Falloon, M.D., an AIDS clinical researcher at the National Institute of Allergy and Infectious Diseases (NIAID). We saw a definite, prolonged interaction. The clear implication is that doctors and patients should be cautious about using garlic supplements during HIV therapy, she says.

For the first three days of the study, nine healthy, HIV-negative volunteers received doses of saquinavir, one of a class of drugs called protease inhibitors that are effective at slowing the progression of HIV infection. The research team drew samples from the volunteers blood to measure their baseline levels of saquinavir in the bloodstream.

Next, the volunteers took garlic caplets twice daily for three weeks. When the researchers again analyzed blood samples, the average overall levels of saquinavir had decreased 51 percent, and the average maximum concentrations had fallen 54 percent.

Even after a ten-day "wash-out" period with no garlic supplements, when the volunteers again used only the protease inhibitor for three days, their blood levels of saquinavir still averaged about 35 percent lower than the expected baseline amount.

The research papers lead author is Stephen C. Piscitelli, Pharm D., formerly with the NIH Clinical Center Pharmacy Department
'"/>

Contact: Gregory Roa
greg.roa@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
5-Dec-2001


Page: 1 2

Related medicine news :

1. How effective are herbal supplements in reducing illnesses in children?
2. Testosterone supplements for elderly men
3. Conference to examine effects of dietary supplements in patients taking blood thinning medications
4. Melatonin supplements offer little or no benefit for the sleep deprived - study says
5. Panel offers recommendations for monitoring adverse events from dietary supplements
6. High doses of vitamin E supplements do more harm than good
7. Study shows high-dose vitamin E supplements may increase risk of dying
8. Herbal, nutritional supplements linked to ocular side effects
9. Moderate exercise and simple dietary supplements significantly reduce risk of atherosclerosis
10. Iron supplements help only certain non-anemic women
11. Study: Many men take dietary supplements to prevent prostate cancer

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Garlic supplements can impede HIV medication

(Date:7/3/2015)... ... 2015 , ... B. E. Smith, the only full-service leadership ... national chief nursing officer recruitment for Jane Phillips Medical Center in ... B. E. Smith has recently placed more than 1,000 healthcare executives into organizations. ...
(Date:7/3/2015)... ... July 03, 2015 , ... Talcum powder attorneys representing clients in national ... Powder Cancer Lawsuit Center website. Just as the previous version did, the new website ... timely lawsuit updates and ovarian cancer warning information. The site is routinely updated with ...
(Date:7/3/2015)... ... ... Selfie on a Stick ” was featured on NewsWatch as part of its monthly ... Forstrom, a technology expert and special reporter for NewsWatch, conducted the review and shared ... smartphone has an incredibly powerful camera built into it. And when someone is traveling ...
(Date:7/3/2015)... ... July 03, 2015 , ... The Celebrity Dresses is currently ... similar to those of celebrities will have the opportunity to get 10% discount on ... ensures that people do not have to use coupon codes or remember redemption codes. ...
(Date:7/2/2015)... (PRWEB) , ... July 02, 2015 , ... sweetFrog Enterprises, ... The opening is now the 19th sweetFrog store located in the Lone Star State. ... of fastest growing companies in 2014. , The store, which opened July 1 at ...
Breaking Medicine News(10 mins):Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 2Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 3Health News:Talcum Powder Lawsuit News: Cancer Attorneys Launch Updated Mobile Site 2Health News:Talcum Powder Lawsuit News: Cancer Attorneys Launch Updated Mobile Site 3Health News:Learn How to Take Selfies like Kendall Jenner 2Health News:Celebrity Fashion Summer Party Dresses on sale at TheCelebrityDresses.com 2Health News:sweetFrog Expands Texas Footprint with Location in Canton 2
(Date:7/4/2015)... July 4, 2015 Adding ... patients with unresectable metastatic colorectal cancer in the ... organ Patients with unresectable metastatic colorectal ... liver experienced the greatest improvement in Progression-Free Survival ... SIR-Spheres Y-90 resin microspheres to a current first-line ...
(Date:7/3/2015)... 2015 A global continuing medical ... and thyroid disorders in Central and South-East ... a major conference dedicated to these diseases. ... Online , Manage Hypertension Online and ... by EXCEMED - combine the world,s top ...
(Date:7/3/2015)... , Mexique, July 3, 2015 ... continue cible les épidémies que sont l,hypertension, le ... par l,intermédiaire de plateformes éducatives gratuites et d,une ...      (Photo: http://photos.prnewswire.com/prnh/20150630/227033 ) , ... diabète en ligne , Prendre en charge ...
Breaking Medicine Technology:New SIRFLOX Study Data Presented at World Congress of Gastrointestinal Cancer 2New SIRFLOX Study Data Presented at World Congress of Gastrointestinal Cancer 3New SIRFLOX Study Data Presented at World Congress of Gastrointestinal Cancer 4Combating Three Major Chronic Diseases in Central and South-East Asia With Medical Education 2Lutter contre trois maladies chroniques majeures en Amérique latine grâce à la formation médicale 2Lutter contre trois maladies chroniques majeures en Amérique latine grâce à la formation médicale 3
Cached News: