HOME >> MEDICINE >> NEWS
Garlic supplements can impede HIV medication

Researchers have found garlic supplements can cause a potentially harmful side effect when combined with a type of medication used to treat HIV/AIDS. Investigators from the National Institutes of Health (NIH) observed that garlic supplements sharply reduced blood levels of the anti-HIV drug saquinavir. The study results appear this week in an on-line edition of Clinical Infectious Diseases (http://www.journals.uchicago.edu/CID/journal/home.html).

In the presence of garlic supplements, blood concentrations of saquinavir decreased by about 50 percent among our study participants, explains the studys senior co-author Judith Falloon, M.D., an AIDS clinical researcher at the National Institute of Allergy and Infectious Diseases (NIAID). We saw a definite, prolonged interaction. The clear implication is that doctors and patients should be cautious about using garlic supplements during HIV therapy, she says.

For the first three days of the study, nine healthy, HIV-negative volunteers received doses of saquinavir, one of a class of drugs called protease inhibitors that are effective at slowing the progression of HIV infection. The research team drew samples from the volunteers blood to measure their baseline levels of saquinavir in the bloodstream.

Next, the volunteers took garlic caplets twice daily for three weeks. When the researchers again analyzed blood samples, the average overall levels of saquinavir had decreased 51 percent, and the average maximum concentrations had fallen 54 percent.

Even after a ten-day "wash-out" period with no garlic supplements, when the volunteers again used only the protease inhibitor for three days, their blood levels of saquinavir still averaged about 35 percent lower than the expected baseline amount.

The research papers lead author is Stephen C. Piscitelli, Pharm D., formerly with the NIH Clinical Center Pharmacy Department
'"/>

Contact: Gregory Roa
greg.roa@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
5-Dec-2001


Page: 1 2

Related medicine news :

1. How effective are herbal supplements in reducing illnesses in children?
2. Testosterone supplements for elderly men
3. Conference to examine effects of dietary supplements in patients taking blood thinning medications
4. Melatonin supplements offer little or no benefit for the sleep deprived - study says
5. Panel offers recommendations for monitoring adverse events from dietary supplements
6. High doses of vitamin E supplements do more harm than good
7. Study shows high-dose vitamin E supplements may increase risk of dying
8. Herbal, nutritional supplements linked to ocular side effects
9. Moderate exercise and simple dietary supplements significantly reduce risk of atherosclerosis
10. Iron supplements help only certain non-anemic women
11. Study: Many men take dietary supplements to prevent prostate cancer

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Garlic supplements can impede HIV medication

(Date:1/22/2015)... Boulder, Colorado (PRWEB) January 22, 2015 Four years ... is Queen – which coincided with the marriage of Avasa & ... album, THE ROAD, which is scheduled for release through White Swan ... heartfelt message that there is a sacred path available to all ...
(Date:1/22/2015)... IPSWICH, Mass. (PRWEB) January 22, 2015 ... Association (AMA) are expanding their relationship in an effort ... journals around the world. While EBSCO has long made AMA ... as a sales agent for The JAMA Network. ...
(Date:1/22/2015)... 22, 2015 JJsHouse.com is a famous dress ... the business announces its latest collection of wedding dresses ... most important issue is the wedding dress on your big ... a woman’s life. Every bride wants to find the most ...
(Date:1/22/2015)... January 22, 2015 Lower-Auto-Insurance.com has released a new ... in a car for reducing the costs of an auto ... also be able to get lower prices for their vehicle insurance ... important role in determining policy costs. Because of this, drivers ...
(Date:1/22/2015)... State Forestry Institute of Mecklenburg-Vorpommern in ... support from GEOSYSTEMS, a dedicated Hexagon Geospatial and Intergraph ... Hexagon Geospatial’s ERDAS APOLLO for cataloging, managing, ... point clouds and documents. This effort will enable the ...
Breaking Medicine News(10 mins):Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2Health News:Driving Safe And Other Factors That Make Auto Insurance Affordable! 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 3
(Date:1/23/2015)... 23, 2015 /PRNewswire/-- Harwood Feffer LLP ( www.hfesq.com ) is ... Advaxis, Inc. ("Advaxis" or the "Company") (NASDAQ: ... fiduciary duties to shareholders. On January 21, ... reporting that Advaxis had misrepresented the clinical data for ...
(Date:1/23/2015)... 23, 2015  Now available for sale, The Armor1 Ankle ... prevents ankle sprains by cushioning the ankle from an ... around the outside of any shoe type and allows ... still offering protection against sprains. With customers in physical ...
(Date:1/23/2015)... Cord Blood America, Inc. ( www.cordblood-america.com ) (OTC Bulletin Board: ... Preliminary Proxy Statement, Schedule 14A, with the U.S. Securities & ... for shareholders detailing why a "YES" vote to increase the ... As we reflect upon the 2014 fiscal year ...
Breaking Medicine Technology:Harwood Feffer LLP Announces Investigation of Advaxis, Inc. 2The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4
Cached News: