HOME >> MEDICINE >> NEWS
Gene responsible for cerebral venous abnormalities found

Note to editors: A team of French researchers is announcing similar findings in a news release embargoed for 4 p.m. EDT Thursday. Their findings will appear in the next issue of Nature Genetics. Due to the nature of the discovery, editors of Human Molecular Genetics are lifting their embargo.

DURHAM, N.C. - A group of American researchers, led by geneticists at Duke University Medical Center, has found one of the genes known to be responsible for an inherited form of cerebral cavernous malformations, a difficult-to-detect condition that can cause massive brain hemorrhages. The scientists said discovery of a cerebral cavernous malformations (CCM) gene could herald important medical advances for individuals and families with this condition--especially for the Mexican-American community, which appears to show a higher incidence of CCM than other ethnic groups.

"With DNA testing, we can now pick up the mutation in kids who are not showing symptoms and follow them closely," said Douglas A. Marchuk, lead geneticist of the Duke group. AThis is the significance of the discovery. We can now help alleviate a great deal of the fear surrounding this condition by focusing our efforts on those children and adults who are truly at risk."

Initial genetic analysis of the Mexican-American families included in the study revealed evidence of a so-called "founder effect," which suggests most of the families are descended from a common ancestor. Of the 21 Mexican-American families included in the study, 16 had the same genetic mutation. Different mutations in the same gene in other non-Hispanic families were included in the study as well.

Cerebral cavernous mutations are lesions of large, abnormally shaped blood vessels in the brain. People with CCM often suffer from seizures (sometimes misdiagnosed as epilepsy) or recurrent, severe headaches B usually beginning in their 20s or
'"/>

Contact: Tracey Koepke
Koepk002@mc.duke.edu
919-684-4148
Duke University Medical Center
30-Sep-1999


Page: 1 2 3

Related medicine news :

1. Failure to count Iraqi casualties is irresponsible, say experts
2. Radon in the home responsible for 9% of lung cancer deaths across Europe
3. Gene mutations responsible for childhood cataracts discovered
4. Advances in understanding brain circuits responsible for tics in Tourettes shed light on disorder
5. No significant genetic difference in viruses responsible for two major Hong Kong SARS outbreaks
6. New studies show factors responsible for enhanced response to music
7. Visceral fat loss after dieting is not necessarily responsible for disease risk improvements
8. More frequent ivermectin treatment could reduce symptoms of disease responsible for river blindness
9. MRI superior to ultrasound in predicting cerebral palsy in preterm infants
10. Fetal heart monitoring ineffective at diagnosing cerebral palsy
11. New guidelines for cerebral palsy recommend early neuroimaging tests

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/24/2017)... ... ... In the Health Care IT campaign, Robert Herjavec discusses health IT security ... will be attacked, but when.” However, he and many others involved highlight a promising ... in auditing and monitoring have taken security in health care a very long way. ...
(Date:2/24/2017)... ... February 24, 2017 , ... Healthcare Associates of McKinney announced ... Ranch building at 8080 State Highway 121, Suite 210, McKinney, Texas 75070. It ... Highway 121. , As the practice has grown, the need for more space has ...
(Date:2/24/2017)... ... February 24, 2017 , ... With ProGlass Prism users now ... . Users have total control over position, rotation, distortion, edge softness, edge blur, chromatic ... Cut Pro X. , With ProGlass Prism users are given the tools and ...
(Date:2/24/2017)... ... February 24, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... this present generation. Yisrayl makes an astounding statement when he says that the ... that the Bible details the current times so plainly that anyone should be able ...
(Date:2/24/2017)... , ... February 24, 2017 , ... Indiana Fiber Network ... the company later this year. Dyer started as the Chairman of the Management ... the establishment of the corporation including the recruitment of investor/owners and development of the ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)...  The particle counters market is projected to ... 275.9 million in 2016, at a CAGR of ... http://www.reportlinker.com/p04718602-summary/view-report.html The growing pharmaceutical and ... growth in manufacturing industries in emerging nations are ... counters. On the other hand, technical limitations of ...
(Date:2/23/2017)... , Feb. 23, 2017 Visiomed, ... and services since 1997, is changing the landscape ... technology providing patients with pro-active, custom-made solutions. Recognizing ... for instant and affordable healthcare without walls, Visiomed ... high-level devices developed with healthcare professionals that is ...
(Date:2/23/2017)... Feb. 23, 2017  Cogentix Medical, Inc. (NASDAQ: CGNT), ... innovative proprietary products for the urology market, will release ... ended December 31, 2016 before the market open on ... will host a conference call and webcast to discuss ... 9, 2017 at 11:00 a.m. Eastern Time (10:00 a.m. ...
Breaking Medicine Technology:
Cached News: