HOME >> MEDICINE >> NEWS
Gene responsible for cerebral venous abnormalities found

Note to editors: A team of French researchers is announcing similar findings in a news release embargoed for 4 p.m. EDT Thursday. Their findings will appear in the next issue of Nature Genetics. Due to the nature of the discovery, editors of Human Molecular Genetics are lifting their embargo.

DURHAM, N.C. - A group of American researchers, led by geneticists at Duke University Medical Center, has found one of the genes known to be responsible for an inherited form of cerebral cavernous malformations, a difficult-to-detect condition that can cause massive brain hemorrhages. The scientists said discovery of a cerebral cavernous malformations (CCM) gene could herald important medical advances for individuals and families with this condition--especially for the Mexican-American community, which appears to show a higher incidence of CCM than other ethnic groups.

"With DNA testing, we can now pick up the mutation in kids who are not showing symptoms and follow them closely," said Douglas A. Marchuk, lead geneticist of the Duke group. AThis is the significance of the discovery. We can now help alleviate a great deal of the fear surrounding this condition by focusing our efforts on those children and adults who are truly at risk."

Initial genetic analysis of the Mexican-American families included in the study revealed evidence of a so-called "founder effect," which suggests most of the families are descended from a common ancestor. Of the 21 Mexican-American families included in the study, 16 had the same genetic mutation. Different mutations in the same gene in other non-Hispanic families were included in the study as well.

Cerebral cavernous mutations are lesions of large, abnormally shaped blood vessels in the brain. People with CCM often suffer from seizures (sometimes misdiagnosed as epilepsy) or recurrent, severe headaches B usually beginning in their 20s or
'"/>

Contact: Tracey Koepke
Koepk002@mc.duke.edu
919-684-4148
Duke University Medical Center
30-Sep-1999


Page: 1 2 3

Related medicine news :

1. Failure to count Iraqi casualties is irresponsible, say experts
2. Radon in the home responsible for 9% of lung cancer deaths across Europe
3. Gene mutations responsible for childhood cataracts discovered
4. Advances in understanding brain circuits responsible for tics in Tourettes shed light on disorder
5. No significant genetic difference in viruses responsible for two major Hong Kong SARS outbreaks
6. New studies show factors responsible for enhanced response to music
7. Visceral fat loss after dieting is not necessarily responsible for disease risk improvements
8. More frequent ivermectin treatment could reduce symptoms of disease responsible for river blindness
9. MRI superior to ultrasound in predicting cerebral palsy in preterm infants
10. Fetal heart monitoring ineffective at diagnosing cerebral palsy
11. New guidelines for cerebral palsy recommend early neuroimaging tests

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Austin residents ... the American College of Mohs Surgery and to Dr. Russell Peckham for medical and ... highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of ... recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at Work ... Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses ...
(Date:6/24/2016)... ... , ... Those who have experienced traumatic events may suffer from a complex ... as drug or alcohol abuse, as a coping mechanism. To avoid this pain and ... a traumatic event. , Trauma sufferers tend to feel a range of emotions, from ...
(Date:6/24/2016)... ... June 24, 2016 , ... The ... in Dallas that it will receive two significant new grants to support its ... PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists for ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... HILL, N.C. , June 24, 2016 /PRNewswire/ ... healthcare decisions and regulators/payers have placed more emphasis ... new environment, patient support programs in the pharmaceutical ... for patients, medications. Consequently, pharmaceutical companies are focusing ... ensure they are providing products and services that ...
(Date:6/24/2016)... 24, 2016 Research and ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" report ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, ... Structural electronics involves electronic and/or electrical components ... replacing dumb structures such as vehicle bodies or ...
(Date:6/24/2016)... PUNE, India , June 24, 2016 ... "Pen Needles Market by Type (Standard Pen Needles, Safety ... 12mm), Therapy (Insulin, GLP-1, Growth Hormone), Mode of Purchase ... published by MarketsandMarkets, This report studies the market for ... is expected to reach USD 2.81 Billion by 2021 ...
Breaking Medicine Technology:
Cached News: