HOME >> MEDICINE >> NEWS
Gene silencer may improve chemo and radiation

The following news tip is based on abstracts to be presented at the annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO), October 19 23, 2003 in Salt Lake City, Utah. The information described below is embargoed until the date and time of presentation.

Like bacteria that resist common antibiotics, cancer cells can survive chemotherapy and radiation. Radiation oncologists at the Johns Hopkins Kimmel Cancer Center report they have found a gene "silencer" that blocks a cancer cell's ability to repair itself after drugs and radiation cause damage.

Engineered pieces of protein-encoding RNA (ribonucleic acid), the mirror image of genes' building blocks, were used to target repair proteins in cancer cells effectively shutting the RNA down. Unable to make the necessary repair proteins, cancer cells then become susceptible to the therapy.

"By dismantling the cancer cell's machinery to produce these repair proteins, we destroy its ability to withstand toxic chemotherapy and radiation treatments," says Theodore DeWeese, M.D., director of the Department of Radiation Oncology at the Johns Hopkins Kimmel Cancer Center.

The researchers saw a decrease in the production of targeted repair proteins by approximately 90 percent, and were able to reduce the amount of radiation needed to damage cells.


'"/>

Contact: Vanessa Wasta
wastava@jhmi.edu
410-955-1287
Johns Hopkins Medical Institutions
20-Oct-2003


Page: 1

Related medicine news :

1. Hormonal treatment improves survival in high-risk prostate cancer patients
2. New technique shows promise for improved straightening of crooked nose
3. Balance and better interactions between primary-care and specialist physicians improve US health
4. Cornea transplants can be improved
5. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
6. New treatment options for some difficult cancers improve survival and quality of life
7. New substance that improves the photodetection of bladder cancer gains market approval
8. Most advanced CT scanner improves imaging of heart, avoids need for surgical inspection
9. Increasing physician volume requirement could improve mammogram accuracy, study concludes
10. Columbia study finds hemophilia therapy dramatically improves outcomes for bleeding stroke
11. OHSU scientists develop MRI approach to improve breast cancer detection

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene silencer may improve chemo and radiation

(Date:8/31/2015)... ... August 31, 2015 , ... ... at Monmouth, was one of the first doctors in the area to perform ... new approach have been impressive: faster recovery, decreased immediate and long-term pain, and ...
(Date:8/31/2015)... ... ... Docs Presents, Dr. Michael Betsy! Dr. Betsy has been reviewed and approved as an ... from Don Bosco Prep in 1990 and was Class Salutatorian. He earned Varsity letters ... senior year. He was inducted into the National Honor Society as a sophomore, was ...
(Date:8/31/2015)... ... 31, 2015 , ... With the FCPX LUT Soft pack from Pixel Film Studios, editors can ... that contains a mathematical formula for modifying an image. The LUT changes every pixel's color ... LUT files. , FCPX LUT Soft requires Final Cut Pro X 10.2 or newer. ...
(Date:8/31/2015)... ... August 31, 2015 , ... How can healthcare meet the ... costs? , In a commentary for The American Journal of Managed Care ... “clinical efficacy,” which would bind parties together in agreements to intervene at the ...
(Date:8/31/2015)... (PRWEB) , ... August 31, 2015 , ... ... and digital marketing communications company announced today that it has officially launched a ... President, the new website and brand refresh are more closely aligned with the ...
Breaking Medicine News(10 mins):Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 2Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 3Health News:NJ Top Docs Presents, Dr. David L. Chalnick! 4Health News:NJ Top Docs Presents, Dr. Michael Betsy! 2Health News:NJ Top Docs Presents, Dr. Michael Betsy! 3Health News:Pixel Film Studios, FCPX Plugin Developer, Releases FCPX LUT Soft 2Health News:How “Clinical Efficacy” Can Rein in Healthcare Costs 2Health News:How “Clinical Efficacy” Can Rein in Healthcare Costs 3Health News:Diablo Publications Launches New Company Website 2Health News:Diablo Publications Launches New Company Website 3
(Date:8/31/2015)... Aug. 31, 2015  Asterias Biotherapeutics, Inc. (NYSE ... emerging field of regenerative medicine, today announced that ... Chicago -based Rush University Medical Center ... of escalating doses of AST-OPC1 (oligodendrocyte progenitor cells) ... complete cervical spinal cord injury (SCI). This represents ...
(Date:8/31/2015)... -- Bionomics Limited (ASX:BNO, ADR:BMICY), a biopharmaceutical company focused ... the treatment of diseases of the central nervous system ... submission has passed review by the US Food and ... 1 clinical trial in patients with metastatic colon cancer ... 31 December 2015. Bionomics, CEO & Managing ...
(Date:8/30/2015)... ANDOVER, Massachusetts y LONDRES, August 30, 2015 ... conectada ofrece una visión holística de l ... de todo el trayecto   ... anunciado hoy el debut europeo de IntelliSpace Cardiovascular ... información que ofrece sofisticadas herramientas para acceder, analizar y ...
Breaking Medicine Technology:Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 2Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 3Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 4Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 5Asterias Biotherapeutics Concludes Recruitment of Initial Safety Cohort of the SCiStar Phase 1/2a Dose-Escalation Clinical Trial of AST-OPC1 for Complete Cervical Spinal Cord Injury 6Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 2Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 3Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 4Philips presenta IntelliSpace Cardiovascular en el Congreso ESC 2015 2Philips presenta IntelliSpace Cardiovascular en el Congreso ESC 2015 3
Cached News: