HOME >> MEDICINE >> NEWS
Gene silencer may improve chemo and radiation

The following news tip is based on abstracts to be presented at the annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO), October 19 23, 2003 in Salt Lake City, Utah. The information described below is embargoed until the date and time of presentation.

Like bacteria that resist common antibiotics, cancer cells can survive chemotherapy and radiation. Radiation oncologists at the Johns Hopkins Kimmel Cancer Center report they have found a gene "silencer" that blocks a cancer cell's ability to repair itself after drugs and radiation cause damage.

Engineered pieces of protein-encoding RNA (ribonucleic acid), the mirror image of genes' building blocks, were used to target repair proteins in cancer cells effectively shutting the RNA down. Unable to make the necessary repair proteins, cancer cells then become susceptible to the therapy.

"By dismantling the cancer cell's machinery to produce these repair proteins, we destroy its ability to withstand toxic chemotherapy and radiation treatments," says Theodore DeWeese, M.D., director of the Department of Radiation Oncology at the Johns Hopkins Kimmel Cancer Center.

The researchers saw a decrease in the production of targeted repair proteins by approximately 90 percent, and were able to reduce the amount of radiation needed to damage cells.


'"/>

Contact: Vanessa Wasta
wastava@jhmi.edu
410-955-1287
Johns Hopkins Medical Institutions
20-Oct-2003


Page: 1

Related medicine news :

1. Hormonal treatment improves survival in high-risk prostate cancer patients
2. New technique shows promise for improved straightening of crooked nose
3. Balance and better interactions between primary-care and specialist physicians improve US health
4. Cornea transplants can be improved
5. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
6. New treatment options for some difficult cancers improve survival and quality of life
7. New substance that improves the photodetection of bladder cancer gains market approval
8. Most advanced CT scanner improves imaging of heart, avoids need for surgical inspection
9. Increasing physician volume requirement could improve mammogram accuracy, study concludes
10. Columbia study finds hemophilia therapy dramatically improves outcomes for bleeding stroke
11. OHSU scientists develop MRI approach to improve breast cancer detection

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene silencer may improve chemo and radiation

(Date:7/31/2014)... have learned that recent fears of invasive lionfish causing ... to control lionfish by fishing derbies and targeted fisheries ... And there,s a simple way to know for sure ... it,s been cooked. , Pacific lionfish were first reported ... have been gaining swiftly in number ever since. They,re ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 Setting goals for ... on blogs on successful tips to weight loss. Fitness on ... for over 8 years, and has worked with 6000 customers ... “We have had the chance to monitor why customers start ... exercising, how long they stick to their program, whether or ...
(Date:7/31/2014)... July 31, 2014 Millions of people ... have had traumatic experiences as a child and some ... work. As a highly experienced NJ cosmetic dentist, ... anxiety during their dental procedure. To help these ... team at Champagne Smiles offer several sedation dentistry techniques. ...
(Date:7/31/2014)... Cape Coral, FL (PRWEB) July 31, 2014 ... the opportunity to take charge of their financial future. ... training for women, has opened registration for 6 upcoming ... designed by women, for women, and with input from ... (Rich Woman and It’s Rising Time) who is passionate ...
(Date:7/31/2014)... July 31, 2014 Dr. Andrew Lian-Jie ... Board of Dermatology, fellowship trained Mohs surgeon that has ... Docs. , After extensive dermatology research training at the ... Dr. Li completed his internship in internal medicine at ... of Pennsylvania in Philadelphia. Dr. Li pursued further training ...
Breaking Medicine News(10 mins):Health News:Invasive lionfish likely safe to eat after all 2Health News:Invasive lionfish likely safe to eat after all 3Health News:Fitness on the Go's Rewards Program Helps Clients Reach Their Goals 2Health News:Champagne Smiles is Thrilled to Now Offer Sedation Dentistry to their Patients 2Health News:The Independent Woman to Offer Financial Workshops in the Los Angeles Area - Developed by Women for Women 2Health News:NJ Top Docs Proudly Presents Approved Provider, Dr. Andrew Li of Warren Skin Care Center 2
(Date:7/31/2014)... , July 31, 2014 Touro University ... has been selected as the recipient of a $150,000 ... will allow the University to increase research and classroom ... creating state-of-the-art technology for the study of health sciences, ... the diverse needs and interests of our students," said ...
(Date:7/31/2014)... SAN FRANCISCO , July 31, 2014 /PRNewswire/ ... ) and Aspira Scientific ( Milpitas, California ... joint venture to develop and commercialize new fluorination ... biologically active molecules has benefited from the use ... metabolism, and combine lipophilicity with polarity to improve ...
(Date:7/31/2014)... ANTWERP, Belgium and LONDON , July ... Organization (CRO) and services provider for the medical industries, announced today ... The United Kingdom has one ... valued at USD 8.9 billion in 2012 and it is projected ... was estimated at USD 234 billion in 2012, equal to 9.5% ...
Breaking Medicine Technology:Touro University California Garners Grant From Long Foundation 2Catylix, Inc. and Aspira Scientific Announce Joint Venture to Commercialize New Fluorination Technologies 2genae Opens Offices in London 2
Cached News: