HOME >> MEDICINE >> NEWS
Generic anti-inflammatory causes significantly fewer GI complications than branded medications

DALLAS Nov. 11, 2004 People in search of pain relief who take the generic anti-inflammatory etodolac suffer 60 percent fewer gastrointestinal complications than those who take similar drugs, according to researchers at UT Southwestern Medical Center at Dallas and the Dallas Veterans Affairs Medical Center.

Use of the drug etodolac instead of drugs like Celebrex or Bextra could save the Veterans health-care system alone about $40 million annually.

"Since etodolac is available as a generic medicine, as much as an 80 percent cost savings can be achieved if patients were to use it rather than branded medications such as Celebrex or Bextra," said Dr. Byron Cryer, associate professor of internal medicine at UT Southwestern, a VA physician and senior author of the study published in the November issue of Gastroenterology. "In the 13 years of etodolac's use in the United States, there have been no reports of increases in cardiovascular events associated with this drug either." Etodolac is a non-steroidal anti-inflammatory drug (NSAID) in the same class as Celebrex. It was first released in the United States in 1991 as a pain reliever and arthritis treatment but has since gone off patent and is generically available.

In the study, Dr. Cryer and his colleagues at UT Southwestern and the Dallas VA evaluated more than 16,000 patients who, over a three-year period from 1999-2001, used either etodolac or naproxen, an over-the-counter pain reliever. Earlier studies indicated etodolac might be safer in the gastrointestinal tract, but none had evaluated its potential effects to reduce gastrointestinal ulcer complications such as bleeding.

When compared to naproxen, etodolac reduced rates of complication by more than 60 percent. This resulted in fewer hospitalizations for bleeding or perforated ulcers in patients taking NSAIDs. Further, the decrease in ulcer complications with etodolac was as great as or greater than those seen in earlier studie
'"/>

Contact: Scott Maier
scott.maier@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
11-Nov-2004


Page: 1 2

Related medicine news :

1. Generic drug use varies widely by state, study reveals
2. Generics slow rising cost of prescription drugs in 2003
3. First quarter prescription drug spending: Generic drugs slow upward trend
4. Generic vs. name brand medications
5. COX-2 inhibitor could be safest anti-inflammatory drug for older people
6. Experts to discuss the affects of non-steroidal anti-inflammatory drugs (NSAIDs)
7. Existing anti-inflammatory drug could help children suffering from an inherited bone disease
8. New anti-inflammatory drug clears Alzheimers provoking protein from brains of mice
9. Insulin sensitizer has anti-inflammatory effect in diabetics
10. Aspirin steps up as anti-inflammatory for arteries
11. New estimates for the causes of child deaths worldwide

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/28/2020)... ... June 28, 2020 , ... World Allergy Organization (WAO), ... Week, from June 28 to July 4, 2020, to the importance of continued ... for “coronavirus disease 2019”, is a disease spreading around the world caused by ...
(Date:6/25/2020)... ANNAPOLIS, Md. (PRWEB) , ... June 25, 2020 , ... ... and treating providers on the key steps when filing appeals for denials of mental ... insurance experts to help educate individuals about their appeal rights and explain the steps ...
(Date:6/24/2020)... ... 24, 2020 , ... At Allerio we have chosen to do things differently. ... We knew it had to be portable, it had to be reliable, it had ... work. , We are proud to announce that Allerio has passed all FCC and ...
(Date:6/24/2020)... ... June 24, 2020 , ... SPH Analytics ... Wexford Physician Hospital Organization (PHO) has successfully deployed SPH’s Population Care™ all-payer population ... of value-based care. Use of Population Care is benefitting more than 77,000 patients ...
(Date:6/24/2020)... (PRWEB) , ... June 24, 2020 , ... Skyroam ... today a partnership with LabWare , the leading provider of enterprise software for ... WiFi connectivity as part of LabWare’s new Portable Disease Surveillance Lab (PDSL) kit. , ...
Breaking Medicine News(10 mins):
(Date:7/2/2020)... ... July 02, 2020 , ... Realty ONE Group International, ... series on its live agent Town Halls, furthering its commitment to its real ... includes special guests and Realty ONE Group leadership discussing social, mental, physical and ...
(Date:7/1/2020)... ... July 01, 2020 , ... Stratodesk today announced a ... available on NComputing devices. Thanks to fantastic new growth and stellar adoption of ... new partnership that will make the full Stratodesk NoTouch OS branded image available ...
(Date:6/25/2020)... LONDON (PRWEB) , ... June 25, 2020 , ... ... Start Competition by Innovate UK to build a distributed ledger platform to store ... end of August, Billon will provide a fully functioning prototype for publishing, sharing ...
Breaking Medicine Technology:
Cached News: