Genes play a role in heart function -- May determine who develops heart failure

WINSTON-SALEM, N.C. Genes play a significant role in heart function, and may partly determine who develops the most common form of heart failure, report researchers from Wake Forest University Baptist Medical Center and colleagues in this month's Hypertension, a journal of the American Heart Association.

"We asked the question what determines differences in heart function from person to person," said Dalane W. Kitzman, M.D., a cardiologist from Wake Forest. "We found a significant portion is actually determined by your genes who is your mother and father. Gene influences were as powerful or even more so than blood pressure level, age, gender, weight, where you live or whether you have diabetes."

Also participating in the research were the University of Minnesota, Boston University School of Medicine, University of Alabama-Birmingham, University of Utah, Washington University School of Medicine and Weill Medical College of Cornell University. In their study of 574 groups of siblings, the researchers used ultrasound to measure how efficiently participants' hearts refilled with blood after each squeezing heart beat. They found that family relationships explained a significant portion as much as half of variability in the heart's filling, which is known as diastolic function. This was the first study to examine the relationship between heart function and heart structure within family members.

"Our research suggests that when you're born your diastolic function may already be programmed," said Kitzman. "A significant part of whether you have good, moderate or poor diastolic function may be determined by genes."

Significantly impaired diastolic function is associated with hypertension, coronary artery disease and the most common type of congestive heart failure. The study included primarily persons with hypertension it is known that many such patients eventually develop congestive heart failure. The researchers speculate that the effects

Contact: Karen Richardson
Wake Forest University Baptist Medical Center

Page: 1 2 3

Related medicine news :

1. Genes for alcohol consumption identified
2. Genes in the interferon system important in SLE
3. Genes can individualize treatment for high blood pressure
4. Genes are of little importance in rheumatoid arthritis
5. New study in Nature demonstrates protection against cell death during heart attack
6. Uric acid and heart disease
7. Researchers search for first sign of congestive heart failure
8. Hopkins begins human trials with donor adult stem cells to repair muscle damaged from heart attack
9. Extreme exertion, emotion can spark repeat heart attacks
10. Men with severe sleep breathing disorder have higher risk of heart problems
11. Red wine protects the heart

Post Your Comments:

(Date:5/21/2020)... ... May 21, 2020 , ... Summit ... milestone to deliver over one million FDA-compliant face shields — designed, engineered and ... meet the critical need for personal protective equipment (PPE) for both front-line health ...
(Date:5/21/2020)... ... May 21, 2020 , ... Having the cushion of an ... has already gained ground with the inherited reputation of quality, innovation, and professionalism. ... guaranteeing an effective way for the ingredients to become immediately available to the ...
(Date:5/21/2020)... ... 2020 , ... Friends of Lisa Campbell, announce that Lisa Campbell, candidate for ... Southeast Advocates (PPSEA). PPSEA educates and lobbies on behalf of women’s health ... reproductive health care. PPSEA educates and lobbies on behalf of women’s health and works ...
(Date:5/21/2020)... ... 2020 , ... ESO , the leading data and software company serving ... 2020 ESO Fire Service Index . The Index looks at key trends across ... turnout time and travel time, the most common property types visited and estimated property ...
(Date:5/21/2020)... ... May 21, 2020 , ... Casenet® LLC today released TruCare ... care management and utilization management at health insurance plans. Developed over two years ... significant usability and automation upgrades to all of its existing features, introduces more ...
Breaking Medicine News(10 mins):
(Date:6/2/2020)... Grove, CA (PRWEB) , ... June 02, 2020 ... ... Dr. Jin Kim, reopens his two periodontal practices in Garden Grove and Diamond ... the Centers for Disease Control and Prevention (CDC), the American Dental Association (ADA), ...
(Date:6/2/2020)... ... June 02, 2020 , ... SCFHP members who call SCFHP’s 24/7 ... and, depending on the inquiry, can now virtually consult with an available physician. Once ... their primary care doctor to ensure seamless care. The nurse advice line with the ...
(Date:5/30/2020)... ... , ... HealthyChildren.org, the official parenting website of the American Academy of Pediatrics ... lucky winners will receive a $200 Amazon.com* gift card. The contest begins June 15 ... day during the event. Winners will be drawn on or about June 22, 2020. ...
Breaking Medicine Technology:
Cached News: