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Genetic amplification (NAAT) test detects HIV more effectively than standard tests in urban study

avoid these problems because it amplifies the HIV viral RNA and detects viral genes instead of viral antibodies or antigens.

NAAT testing has been used in the U.S. as an investigational screening test for donated blood since 1999 and was approved for use in 2002 by the FDA. According to a study by the National Institutes of Health (New England J. of Medicine, Aug. 19, 2000), the test has helped prevent the transmission of approximately five HIV-1 infections and 56 hepatitis C virus infections each year since it was initiated for screening donor blood.

"Adding NAAT-based screening to standard HIV testing for can identify people with acute HIV infection earlier when they may be most infectious and at risk for spreading the virus. Then they can be referred for prevention and treatment services earlier before they develop clinical symptoms," Dr. Priddy says. "Early detection and intervention for patients with acute HIV infection may be key in stopping the spread of drug-resistant HIV. Our results show that urban STD and drug clinics and HIV testing sites should consider adopting HIV testing that includes NAAT."


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Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
25-Feb-2005


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