The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> MEDICINE >> NEWS
Glue ear could be caused by gastric juices

N.B. Please note that if you are outside North America the embargo date for this Lancet press material is 0001 hours UK time Friday 8th February 2002.

Glue eara frequent cause of deafness in childrencould be a result of gastric reflux, which results in stomach proteins accumulating in the middle ear via the Eustachian tube, suggest authors of a research letter in this weeks issue of THE LANCET.

Glue ear is common among children after middle-ear infections (otitis media); effusion, produced by mucus cells, occurs in the middle ear and cannot be cleared. It is a particular problem for young children because of the angle and immaturity of the Eustachian tube, and the supine position in which infants are often placed. There are thought to be several causes of glue ear, including bacterial and viral infection, allergy, and the presence of stomach acid (and the enzyme pepsin) as a result of gastric reflux. Andrea Tasker from the University of Newcastle upon Tyne, UK, and colleagues investigated reflux of gastric juice as a potential cause of glue ear.

The investigators measured pepsin concentrations in middle ear effusions from children in Newcastle upon Tyne and Nottingham, UK. 45 (83%) of 54 effusions contained pepsin/pepsinogen at concentrations of up to 1000-fold greater than those in blood (used for comparison).

Andrea Tasker comments: Gastric juice that refluxes into the middle ear will cause transient damage to the Eustachian tube and the middle-ear mucosa before it can be neutralised, resulting in inflammation. This provides ideal conditions for secondary bacterial colonisation, leading to the symptoms associated with glue ear. We therefore think that anti-reflux treatment could prevent otitis media with effusion.


'"/>

Contact: Richard Lane
richard.lane@lancet.com
44-20-7611-4076
Lancet
7-Feb-2002


Page: 1

Related medicine news :

1. Charcoal and forest management could reduce greenhouse gas levels & save lives in Africa
2. Novel therapy tested in mice could chase away cat allergies
3. Costs of antidepressants could have funded effective alternatives
4. Emergency clopidogrel could save thousands of lives46,000-patient heart attack trial results
5. Blood pressure treatment could cut risk of strokes and heart attacks
6. Proteins found in urine of pregnant women could help diagnose preeclampsia
7. Three out of the four million newborn babies who die each year could be saved
8. Increasing physician volume requirement could improve mammogram accuracy, study concludes
9. Chemicals in apples could reduce the risk of breast cancer, Cornell study in rats suggests
10. Training could remove racial bias from police reactions
11. Test could improve detection of prion disease in humans

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Glue ear could caused gastric juices

(Date:11/25/2009)...SANGELES,Nov.25/PRNewswire-USNewswire/--TheBlackAI...etermineexecutiveleadershipfor2010. ,, ThenewBo...altiesinpublicpolicy,law,finance,governmenthealthp...oardalsocomesfromawiderangeofpersonalbackgroundsin...livingwithHIVthemselves,andrepresentingmultipleage...
(Date:11/25/2009)...ers have found evidence of a statistically signifi...g patients whose estrogen receptor (ER)-positive t...ha; at serine-118 (ER-alpha S118-P), according to ... in the Journal of the National Cancer Institute ...esistant to tamoxifen. Preclinical studies have sh...
(Date:11/25/2009)... already used to fight rheumatoid arthritis, could... , WEDNESDAY, Nov. 25 (HealthDay News) -- A ... and rheumatoid arthritis now also shows some prom...1 diabetes. , The drug, rituximab (Rituxan), he...ulin, even though the disease had destroyed some o...
(Date:11/25/2009)...sitive note, CDC sees few signs of trouble with th...(HealthDay News) -- The ongoing H1N1 swine flu pan...neumonias among younger patients, a U.S. health of...ease in serious pneumococcal infections around the...onal Center for Immunization and Respiratory Disea...
(Date:11/25/2009)...E, Mass. -- A cancer vaccine carried into the body...nt is the first to successfully eliminate tumors i...nal Science Translational Medicine . , The new ...sts at Harvard University, uses plastic disks impr... under the skin to reprogram the mammalian immune ...
Breaking Medicine News(10 mins):Health News:Black AIDS Institute Announces 2010 Board Election Results 2Health News:Type 1 Diabetes May Have a New Foe 2Health News:Type 1 Diabetes May Have a New Foe 3Health News:Swine Flu Tied to Rise in Pneumonias Among Young 2Health News:Swine Flu Tied to Rise in Pneumonias Among Young 3Health News:Swine Flu Tied to Rise in Pneumonias Among Young 4Health News:Implant-based cancer vaccine is first to eliminate tumors in mice 2
(Date:11/25/2009)...sResearchGroup,Inc.releasedWave1ofits LaunchTrend...ndicatedmarketresearchprojecttrackingthelaunchofCe...ughthefirstsixmonthsofavailability.Eachwaveofthere...matologistsandqualitativeinformationfromasubsetof2...use,typicalpatienttypes,productperceptions,promoti...
(Date:11/25/2009)...irstCall/--FormanyofthemillionsofhearingimpairedAm...hearingloss ,theholidaysmaynotbeallthathappy,saysa...sidentofHearUSA(Amex: EAR ),oneofAmerica,slargesth...elinkedhearinglosstostress,frustration,andsocialis...ringswithfamiliesandfriends,whenmanyofthosewithhea...
(Date:11/25/2009).../--AMPACFineChemicalsLLC(AFC),asubsidiaryofAmerica...atitreceivedtheEnvironmentalResponsibilityandSusta...mit,sponsoredbytheCaliforniaManufacturersandTechno...sociation(IEA)andtheChemicalIndustryCouncilofCalif...awardavailablefromallthreeorganizationsandgainssub...
Breaking Medicine Technology:Despite Managed Care Obstacles, Interest and Anticipated Use of Centocor Ortho-Biotech's New Psoriasis Agent Stelara (ustekinumab) is High 2For Millions With Untreated Hearing Loss, Holiday Season Can be Especially Difficult 2AMPAC Fine Chemicals Receives Prestigious Award at California's Annual Statewide Environmental Summit 2Caraco Pharmaceutical Laboratories Ltd Markets Generic Imitrex 28R 29 Tablets 54270 1Caraco Pharmaceutical Laboratories Ltd Markets Generic Imitrex 28R 29 Tablets 54270 2HearUSA Makes Hearing Aids and Care Available to AARP Members 54269 1HearUSA Makes Hearing Aids and Care Available to AARP Members 54269 2HearUSA Makes Hearing Aids and Care Available to AARP Members 54269 3HearUSA Makes Hearing Aids and Care Available to AARP Members 54269 4West to Present at the Ninth Annual CJS Securities New Ideas Summer Conference 54267 1
Other News:
...s, scientists have determined that drugs that bloc...protect brain cells from damage triggered by an ov...duce the same effect in humans, they could become ...amage that can result from hypoglycemic shock, als...
...t emitted by a star makes it extremely difficult t...hnique that combines signals from two or more tele...ficial solar eclipse, 'neutralising' the effects o...rom a planet can be detected. ... ...European spac...
...o take a commonly prescribed yet problematic drug ...ay soon have a hassle-free alternative, according ...ine. Results from a 7,329-person international stu...prevents strokes as effectively as Coumadin withou...
Hearing loss in adulthood may be programmed at birth, and short people may be particularly susceptible, say researchers from Sweden in this week's BMJ.......Their conclusions are based on the theory (
health news:Experimental drugs reduce neuron death in rats following insulin shock 2health news:Experimental drugs reduce neuron death in rats following insulin shock 3health news:Experimental drugs reduce neuron death in rats following insulin shock 4health news:Experimental drugs reduce neuron death in rats following insulin shock 5health news:Space science joins battle against cancer 2health news:Hassle-free stroke prevention offered by new drug, Stanford researcher says 2
... combination of chemotherapy and radiation therapy...void additional surgery to the neck, according to ...the Multidisciplinary Head and Neck Cancer Symposi...merican Society for Therapeutic Radiology and Onco...
...rsity of Illinois at Urbana-Champaign have develop...or optical microscopy that can produce crisp, thre...a....Called Interferometric Synthetic Aperture Mic...agnetic resonance imaging did for nuclear magnetic...
...licy proposals to advance patient-centered primary...of Physicians (ACP) in its annual report on The St...ill fundamentally change the way that primary care.... The U.S. health care system is facing a collapse...
...per with proposals to restructure conventional Ame... was released today by The American College of Phy...f the Nation's Health Care."... "A System in Need ...rt Patient-Centered Care" offers a series of nine ...
health news:Novel computed imaging technique uses blurry images to enhance view 2health news:Comprehensive reforms to move toward patient-centered care released by ACP 2health news:Comprehensive reforms to move toward patient-centered care released by ACP 3health news:A system in need of change -- restructuring payment policies to support patient-centered care 2