Grape seed extract help speed up wound recovery, study suggests

COLUMBUS, Ohio Grape-seed extract may help skin wounds heal faster and with less scarring, a new study suggests.

The extract seemed to aid wound healing in two ways: It helped the body make more of a compound used to regenerate damaged blood vessels, and it also increased the amount of free radicals in the wound site. Free radicals help clear potentially pathogenic bacteria from a wound.

In two related experiments, the researchers tested the effects of grape-seed extract on mice and on human skin cells. It's the first evidence suggesting that a natural extract could have such a profound effect on wound healing, said Chandan Sen, a study co-author and director the Laboratory of Molecular Medicine at Ohio State University's Heart and Lung Research Institute.

"We saw the healing effects grape-seed extract had on wounds from day one," said Sen, who is also an assistant professor of surgery at Ohio State. "It seemed to enhance the formation of epidermal tissue as well as the deposition of connective tissue."

The researchers treated skin wounds on mice with a topical formulation of grape seed proanthocyanidin extract (GSPE). Proanthocyanidin, one of the main ingredients in grape-seed extract, is thought to be a potent

Contact: Chandan Sen
614-247 7786
Ohio State University

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