HOME >> MEDICINE >> NEWS
Growth factor grows stem cells that help heal hearts

Orlando, Fla., Nov. 11 A drug that stimulates bone marrow to produce stem cells helped regenerate damaged heart muscle in one of the first studies of its kind, according to a report presented at the American Heart Association's Scientific Sessions 2003.

The drug, granulocyte colony stimulating factor (G-CSF), treats some forms of cancer. It stimulates bone marrow to produce the different types of blood cells, including white blood cells that can become depleted after disease or chemotherapy.

G-CSF might help repopulate the heart's muscle cells, which in turn could help repair the damaged heart, said lead author Chris A. Glover, M.D.

"Research has shown that there are cells in the heart that come from bone marrow stem cells. We hypothesized increasing these cells after a heart attack may help the heart regenerate heart muscle cells, and this is supported by our results," said Glover, assistant professor of medicine at the University of Ottawa and the Ottawa Heart Institute in Ontario.

"The main limitation of this study is that it included only five patients and was not randomized. On the other hand, the study's strengths are that it explores the use of a novel therapy, which is a simple treatment that any physician could use to improve the outlook for heart attack patients."

All five patients who received G-CSF had anterior wall heart attacks, also known as large heart attacks. They had emergency angioplasty, a procedure to open their vessels by inserting an inflatable balloon that compresses the plaque and restores blood flow.

"We wanted patients with large heart attacks in this study, since they have the most to benefit from a therapy that could regenerate the heart," Glover said.

Within two weeks of the patients' heart attack, doctors injected G-CSF in the fatty skin layers once a day for four consecutive days.

Researchers measured CD34 cells, a marker of stem cells, to find out if the drug was stimulating
'"/>

Contact: Carole Bullock
carole.bullock@heart.org
214-706-1279
American Heart Association
11-Nov-2003


Page: 1 2

Related medicine news :

1. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
2. Growth hormone, sex steroid combination not ready for prime time
3. New Technique Induces Growth Across Spinal Cord Injury
4. Growth-Hormone Deficient Babies Are Normal Length At Birth, UB Study Finds
5. Inhibiting Growth Of New Blood Vessels Reduces Heart Disease Plaque In Mice
6. New Chemicals Could Lead To First Bone Growth Pill
7. Novel Biological Interaction Found To Explain Blood Vessel Growth To Tumors
8. Common Dental Bleaching Ingredient May Promote Growth Of Precancerous Oral Lesions, UB Dental Researchers Find
9. Clinical Trial Demonstrates Experimental Growth Factor Increases Eligibility For Autologous Stem Cell Transplantation
10. National Jewish Pediatric Asthma Specialist Urges Monitoring Growth When Using Nebulized Glucocorticoids As An Asthma Treatment In Children
11. Health Workers May Experience Costly Dislocation As Health Spending Growth Slows

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/19/2019)... ... November 18, 2019 , ... “Impact of the ... Kindy has been named No. 1 International Best Seller and Hot New Release ... Energy Healing, Nosology, and Alternative Medicine. , Kindy’s study investigated the impact ...
(Date:11/16/2019)... ... 2019 , ... MemoryCare.com , a comprehensive resource for ... Care Facilities in Amarillo, Texas. The guide identifies 5 memory care communities based ... the Alzheimer’s Association , 5.6 million people age 65 and older are ...
(Date:11/15/2019)... ... 2019 , ... Anxiety is sweeping the country in epidemic ... current figures of adults who suffer at 40 million, yet only 36.9% of ... different ways, including Post Traumatic Stress Disorder (PTSD), phobias, Generalized Anxiety Disorder (GAD), ...
(Date:11/14/2019)... ... November 14, 2019 , ... Inland Detox, Inc. is proud ... gastronomical masterpiece for former President Vicente Fox of Mexico. The Chefs Latinos Guanajuato Festival ... President Fox was born and raised on Saturday, November 9, 2019. The event featured ...
(Date:11/14/2019)... (PRWEB) , ... November 14, 2019 , ... ... treatments for cancers and other serious diseases, announced it will have 5 poster ... at the upcoming 24th Annual Society for Neuro-Oncology SNO Meeting in Phoenix, beginning ...
Breaking Medicine News(10 mins):
(Date:11/16/2019)... ... November 15, 2019 , ... Cosmetic surgery continues to be popular in the ... to undergo cosmetic procedures all throughout the United States, the final price can be ... fees and the extent of the work that needs to be performed to achieve ...
(Date:11/15/2019)... CORAL SPRINGS, Fla. (PRWEB) , ... November 15, 2019 , ... ... a continued charitable partnership. Hope For The Warriors was founded by the ... the effects war can have on service members and their families. For the past ...
(Date:11/14/2019)... ... 2019 , ... Algae Health Sciences, a division of BGG, ... on brain health. , In the first study (done in USA), ... overall mood state [psychological well-being] were found after 8 weeks in healthy subjects ...
Breaking Medicine Technology:
Cached News: