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HIV patients may be at risk of heart problems when taking protease inhibitor drugs

r findings suggest that as a class, protease inhibitors may predispose individuals to QT interval problems or torsade de pointes," Dr. Badley says. Dr. Ackerman adds, "Long QT-adverse events are serious side effects in drugs, but with extra caution from physicians, this risk that we've identified can be managed, and that's the good news."

Collaborations

The research team also included Blake Anson, Ph.D., University of Wisconsin; Joel G.R. Weaver, M.D., Mayo Clinic and the University of Ottawa; Omobosola Akinsete, M.D., and Keith Henry, M.D., University of Minnesota and HIV Program of Hennepin County Medical Center, Minneapolis.


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Contact: Bob Nellis
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
17-Feb-2005


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