HOME >> MEDICINE >> NEWS
HRT and breast cancer: better prognosis more likely due to frequent screening than hormone use

While women with breast cancer who have used hormone-replacement therapy are known to have better survival odds than those who've never taken hormones, the advantage is due, most likely, to more-frequent mammography screening rather than the effect of the hormones on tumor biology, according to new findings by researchers at Fred Hutchinson Cancer Research Center.

"Most of the good prognostic factors that have been ascribed to HRT - such as smaller tumor size and earlier cancer stage at diagnosis - may simply be an artifact of screening," said Janet Daling, Ph.D., lead author of the paper, which appears in the current (November) issue of Cancer Epidemiology, Biomarkers and Prevention.

"In many cases probably the HRT itself is doing nothing, other than getting women to the doctor once a year for a prescription renewal - and a mammogram," said Daling, a member of Fred Hutchinson's Public Health Sciences Division. Daling and co-authors from five study sites nationwide reported that 90 percent of women who used combination estrogen/progestin HRT had undergone a screening mammogram within two years of breast-cancer diagnosis. In contrast, only 65 percent of women with breast cancer who'd never used HRT had undergone a mammogram during that time period.

The difference in tumor size between the two groups was significant. Among women who'd been screened within two years of diagnosis, 67 percent had tumors smaller than 2 centimeters (about the size of a pea), whereas only about 34 percent of women who hadn't been screened had tumors that small.

"I was floored when I saw this data," Daling said, "because tumor size is one of the most important prognostic factors in breast cancer. The difference in the size of the tumors between the two groups was staggering. If that isn't a good advertisement for mammography screening, then I don't know what is."

The findings were based on data from the Women's CARE (Contraceptive and Reproductive E
'"/>

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
2-Dec-2003


Page: 1 2 3 4

Related medicine news :

1. International breast cancer prevention study launches in the United States and Canada
2. Unexpected benefit seen in treating HER-2 breast cancer with new preoperative drug combo
3. Risk of cardiac death after radiotherapy for breast cancer has declined, study finds
4. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
5. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women
6. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
7. Postmenopausal breast cancer survivors at increased risk for bone fractures
8. Nursing mothers having surgery -- How long a wait to breastfeed safely?
9. Researchers close in on breast cancer vaccine
10. Simple question from your doctor can help identify your risk for breast cancer
11. Non-invasive and invasive breast cancers share the same genetic mutations

Post Your Comments:
(Date:4/17/2014)... By discovering a new mechanism that allows blood to ... UC Irvine and the Salk Institute have opened the ... stroke-induced brain damage. , A complex and devastating neurological ... primary reason for disability in the U.S. The blood-brain ... blood-borne material into the brain, causing the permanent deficits ...
(Date:4/17/2014)... NEW YORK April 17, 2014 EcoHealth Alliance, ... public health issues, published a comprehensive review today examining ... and Marburg virus. The review calls for improved global ... such as the recent outbreak of Ebola in West ... in the countries of Guinea and Liberia. According ...
(Date:4/17/2014)... has the potential to ward off depression among retirees, ... published online in The Journals of Gerontology, ... In the article " Internet Use and Depression Among ... Analysis ," the authors report that Internet use reduced ... among their study sample. , Late-life depression affects ...
(Date:4/17/2014)... Population Council scientists and their partners have found that ... prevent the transmission of multiple sexually transmitted infections (STIs) ... herpes simplex virus 2 (HSV-2), and human papillomavirus (HPV). ... the gel is effective against multiple strains of HIV, ... against all three viruses of at least eight hours ...
(Date:4/17/2014)... 2014 Meaningful long-term survival is possible for ... abdomen when treated with cytoreductive surgery with Hyperthermic ... analysis by physicians at Wake Forest Baptist Medical ... reported, single-center experience with cytoreductive surgery and HIPEC, ... analysis of 20 years, worth of patient data ...
Breaking Medicine News(10 mins):Health News:Study IDs new cause of brain bleeding immediately after stroke 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 3Health News:Internet use may cut retirees' depression 2Health News:Animal study provides first evidence that gel can prevent multiple virus transmission in vagina/rectum 2Health News:20 years of data shows treatment technique improvement for advanced abdominal cancer 2
(Date:1/14/2014)... 14, 2014 /PRNewswire-iReach/ -- Acumed,s new SLIC Screw System ... accompanying instrumentation to place and insert the screw accurately ... tissue (e.g. ligament) repair or reconstruction as it holds ... (Photo: http://photos.prnewswire.com/prnh/20140114/MN45636 ) The ...
(Date:1/14/2014)... 2014   NuAire , a manufacturer of ergonomically designed laboratory ... Koki of Japan to sell and ... . NuAire will utilize its network of sales professionals throughout ... to offer assistance in application use, product benefits and ...
(Date:1/14/2014)... Jan. 14, 2014   Oligomerix, Inc. , a privately held ... Alzheimer,s disease (AD) and related neurodegenerative disorders, announced today ... Valhalla, NY as of January 15, 2014 ... New York Medical College. Oligomerix, which is ...
Breaking Medicine Technology:Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 3NuAire announces sales and service of Hitachi Koki centrifuges in North America 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2
Cached News: