HOME >> MEDICINE >> NEWS
HRT and breast cancer: better prognosis more likely due to frequent screening than hormone use

While women with breast cancer who have used hormone-replacement therapy are known to have better survival odds than those who've never taken hormones, the advantage is due, most likely, to more-frequent mammography screening rather than the effect of the hormones on tumor biology, according to new findings by researchers at Fred Hutchinson Cancer Research Center.

"Most of the good prognostic factors that have been ascribed to HRT - such as smaller tumor size and earlier cancer stage at diagnosis - may simply be an artifact of screening," said Janet Daling, Ph.D., lead author of the paper, which appears in the current (November) issue of Cancer Epidemiology, Biomarkers and Prevention.

"In many cases probably the HRT itself is doing nothing, other than getting women to the doctor once a year for a prescription renewal - and a mammogram," said Daling, a member of Fred Hutchinson's Public Health Sciences Division. Daling and co-authors from five study sites nationwide reported that 90 percent of women who used combination estrogen/progestin HRT had undergone a screening mammogram within two years of breast-cancer diagnosis. In contrast, only 65 percent of women with breast cancer who'd never used HRT had undergone a mammogram during that time period.

The difference in tumor size between the two groups was significant. Among women who'd been screened within two years of diagnosis, 67 percent had tumors smaller than 2 centimeters (about the size of a pea), whereas only about 34 percent of women who hadn't been screened had tumors that small.

"I was floored when I saw this data," Daling said, "because tumor size is one of the most important prognostic factors in breast cancer. The difference in the size of the tumors between the two groups was staggering. If that isn't a good advertisement for mammography screening, then I don't know what is."

The findings were based on data from the Women's CARE (Contraceptive and Reproductive E
'"/>

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center
2-Dec-2003


Page: 1 2 3 4

Related medicine news :

1. International breast cancer prevention study launches in the United States and Canada
2. Unexpected benefit seen in treating HER-2 breast cancer with new preoperative drug combo
3. Risk of cardiac death after radiotherapy for breast cancer has declined, study finds
4. Study shows risk of cardiac death after radiation for breast cancer has dramatically decreased
5. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women
6. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
7. Postmenopausal breast cancer survivors at increased risk for bone fractures
8. Nursing mothers having surgery -- How long a wait to breastfeed safely?
9. Researchers close in on breast cancer vaccine
10. Simple question from your doctor can help identify your risk for breast cancer
11. Non-invasive and invasive breast cancers share the same genetic mutations

Post Your Comments:
(Date:3/3/2015)... Burlington, VT (PRWEB) March 03, 2015 In ... world’s largest environmental networks, will kick off a new campaign, ... join the network’s businesses, nonprofits, and ambassadors in their quest ... Planet will work with several of its members and partners, ... Johnson’s All At Once network, to raise awareness for food ...
(Date:3/3/2015)... While it is clear that the prospect of ... drivers are signing up to UBI policies, more mature ... enticed. Due to current regulations, the application of UBI ... Its full capability is starting to be realised in ... breakdown services are at the top of the value-added ...
(Date:3/3/2015)... 2015 Today is International Ear Care ... the occasion to applaud and promote the launch of ... Health Organization (WHO) for stemming the threat of noise-induced ... young people to practice safe listening when they recreate, ... or sporting events, or engaging in other forms of ...
(Date:3/3/2015)... March 03, 2015 The Calistoga Chamber of ... of All Weekends,” taking place Friday, March 27, through Sunday, ... Pretty Muddy 5K fun run, restaurant and bar crawl, lodging ... open to women, ages 14 and older. , A variety ... getting in on the action by offering Mudder of All ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 In a ... Morning Edition, science correspondent Shankar Vedantam shared ... Pennsylvania about the drastic decrease in hand-hygiene compliance that occurs ... that the problem could be solved in part by alerts ... hygiene when they enter and exit a patient’s room. ...
Breaking Medicine News(10 mins):Health News:1% For the Planet Asks Consumers to “Know Your Source” 2Health News:TU-Automotive: Wawanesa Insurance to Discuss How UBI Can Produce Happy, Loyal Customers 2Health News:ASHA Applauds Launch of New WHO Campaign 2Health News:Visit Calistoga Hosts Mudder of All Weekends Girlfriend Getaway Event 2Health News:Visit Calistoga Hosts Mudder of All Weekends Girlfriend Getaway Event 3Health News:BIOVIGIL Hygiene Technologies Answers Call for Hand Hygiene Alerts on Badges 2Health News:BIOVIGIL Hygiene Technologies Answers Call for Hand Hygiene Alerts on Badges 3
(Date:3/3/2015)... NEW YORK , March 3, 2015  This industry report package ... and future outlook for safety glass in the world and in the ... the package includes country reports from the following countries: ... , Germany , Italy , ... Turkey , United Kingdom , United ...
(Date:3/3/2015)...  UnaliWear announces the market preview of its first ... guards against wandering and provides support for falls and ... the Kanega watch ( http://www.UnaliWear.com ) – is also ... speech interface rather than buttons, use cellular and Wi-Fi ... The watch goes wherever the wearer goes ...
(Date:3/3/2015)... , March 3, 2015  Columbia Laboratories, Inc. ... " or "the Company"), a specialty pharmaceutical company focused ... will present at the 27th Annual ROTH Conference, which ... Laguna Niguel in Dana Point, California ... 11 at 9:00 a.m. Pacific Time (12:00 p.m. Eastern ...
Breaking Medicine Technology:Global Safety Glass Market to 2019 - Market Size, Top 10 Countries, Trends, and Forecasts 2UnaliWear's Wearable For Seniors Extends Independence With Advanced Technology 2
Cached News: