HRT pills, patches and heart disease risk factors

University Park, Pa. --- The different effects of oral vs. transdermal hormone replacement therapy (HRT) on heart disease risk factors make a woman's choice between taking estrogen via pill or patch more than a convenience issue, says a Penn State researcher.

Dr. Sheila West, assistant professor of biobehavioral health, is lead author of a new study, which is one of the first to look at the effects of the estrogen pill vs. the patch on heart disease risk factors beyond blood pressure and cholesterol.

The study results showed that the HRT pill and patch had similar positive effects on the tightness or constriction of blood vessels, total cholesterol and low-density lipoprotein cholesterol (LDLs, the "bad" cholesterol). However, the research team found different effects on high density lipoprotein (HDLs, the "good" cholesterol) and triglycerides depending on whether the woman was taking HRT pills or using a patch to deliver estrogen.

In addition, the study found that women who used either the estrogen pill or the patch had lower blood pressure during psychological stress. West says this blood pressure lowering effect might be a new way to explain how estrogen protects women from heart disease.

"Women may have special reasons for wanting to choose the patch or the estrogen pill," says the Penn State researcher. "If, for example, a woman has low HDLs, she might choose oral HRT since subjects in our study and other studies showed no change in the beneficial HDLs while on transdermal therapy. "On the other hand, a woman might want to select the patch if her triglycerides were already high, since oral therapy increases this factor which is associated with a higher risk of heart disease." The study is detailed in the April issue of the American Journal of Obstetrics and Gynecology in a paper, "Transdermal Estrogen Reduces Vascular Resistance and Serum Cholesterol in Postmenopausal Women." West conducted the study as part of her

Contact: Barbara Hale
Penn State

Page: 1 2 3

Related medicine news :

1. Taking pills, even if placebo, predicts better survival in heart failure
2. Low-dose oral contraceptives are as protective against ovarian cancer as are older, high-dose pills, find University of Pittsburgh researchers
3. Free nicotine patches increase short-term smoking quit rates
4. New ways identified to treat lazy eye in children: Beyond eye patches and daily drops
5. Success of nicotine patches linked to genetic make-up
6. Oestrogen-replacement therapy from skin patches not associated with venous blood clots
7. New research says better social skills not nicotine patches help smokers quit
8. Nicotine patches and gum may pose health hazards
9. Pharmacologist tip sheet: Migraine patches, nicotine therapies, allergy medication interference...
10. New study in Nature demonstrates protection against cell death during heart attack
11. Uric acid and heart disease

Post Your Comments:

(Date:9/1/2020)... SEATTLE (PRWEB) , ... September 01, 2020 , ... ... that it has completed $3 million convertible note financing, which will be used ... , With the funds from this financing, the company will continue to expand ...
(Date:8/31/2020)... ... August 31, 2020 , ... The ... to funding innovative lymphoma research and serving the lymphoma community through a comprehensive ... 10th Anniversary of Blood Cancer Awareness Month (BCAM) and its international Light ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... higher-learning opportunities through high-quality, career-relevant, and affordable online education – is proud to ... , Among the first of its kind in the nation, the 60-credit ...
(Date:8/31/2020)... ... August 31, 2020 , ... Dr. Chang has over 20 ... and other developmental disabilities, as well as supporting staff in caring for patients ... school consultation, and staff development. She joined the company in 2015 as Chief ...
(Date:8/28/2020)... ... August 28, 2020 , ... The ... a customized Lighthouse Health & Wellness mobile app and web-portal. NCPCV received a ... Solutions Foundation awards grants each year to organizations, such as Destination Imagination, which ...
Breaking Medicine News(10 mins):
(Date:8/26/2020)... CHARLES, Mo. (PRWEB) , ... ... ... Services, a member of Eurofins BioPharma Services, Laboratory Testing division, expands its ... the existing suite of Flow Cytometry platforms available. With industry-leading biomarker solutions, ...
(Date:8/26/2020)... (PRWEB) , ... August 26, ... ... Holdings company today announced that it has entered into definitive agreement to ... CME/CE, primarily focused on pharmacists and pharmacy technicians. , CEA represents ...
(Date:8/26/2020)... ... August 26, 2020 , ... Crossroads Hospice & ... CHC and CPCO to her name. , That’s thanks to her completion of ... the Certified Professional Compliance Officer (CPCO.) , The CHC is designed to mitigate ...
Breaking Medicine Technology:
Cached News: