HOME >> MEDICINE >> NEWS
Higher rate of improvement, lower rate of adverse effects with clarithromycin for acute exacerbations of chronic bronchitis

San Francisco, Calif., May 23, 2001 Data from a study presented today at the 97th annual meeting of the American Thoracic Society show that patients who were treated with clarithromycin (Biaxin, Abbott Laboratories) for an acute exacerbation of chronic bronchitis (AECB), experienced a higher rate of improvement and fewer adverse events than patients who were treated with other leading antibiotics, including levofloxacin (Levaquin, Johnson & Johnson) and cefuroxime axetil (Ceftin, GlaxoSmithKline).

According to the study results, more patients with chronic bronchitis who were treated with clarithromycin improved compared to patients treated with the other antibiotics, said Lee R. Weiss, M.D., F.A.C.E.P., chairman, department of emergency medicine, Knox Community Hospital, Mount Vernon, Ohio, and lead investigator of the study. Specifically, clarithromycin offers an important alternative in the treatment arsenal for patients with an acute exacerbation of chronic bronchitis, as it offers a higher cure rate and fewer side effects.

Study Results

A randomized, prospective, multi-center study of 283 patients, compared clarithromycin 500 mg BID, levofloxacin 500 mg QD, and cefuroxime axetil 250 mg BID in patients with AECB. Each drug was administered for 10 days. For six weeks prior to randomization, patients with suspected AECB completed a questionnaire designed to assess disease severity and antimicrobial treatment. Eligible patients were required to have chest radiographs negative for pneumonia or structural lung disease (other than chronic obstructive pulmonary disease).

Among the eligible patients, 97 were randomized to clarithromycin, 94 to levofloxacin, and 92 to cefuroxime axetil. No significant difference was observed in disease between any groups at the start of the study. Among evaluable patients, clinical cure/improvement was observed in 87.9 percent (80 of 91) of those treated with clarithromycin, 87.3 percent (76 of 87) of tho
'"/>

Contact: Donna Lindquist
312-856-8873
Porter Novelli
22-May-2001


Page: 1 2

Related medicine news :

1. Higher folate intake associated with decreased risk of hypertension in women
2. Higher incidence of rejection following early steroid withdrawal
3. Higher radiation doses help some lung cancer patients live longer
4. Higher doses of cancer drug imatinib proven effective and safe
5. Higher dose of Gleevec leads to increased remission in CML patients
6. Higher education or larger brain size may protect against dementia later in life, new study finds
7. Higher cost sharing reduces plans drug expenditures, but boosts enrollee costs
8. Higher nocturnal blood pressure predictive of kidney disease in diabetes
9. First quarter 2002 prescription drug spending: Higher again, but rate of increase drops
10. Cancer Rates In Children Of Nuclear Industry Employees No Higher Than General Population In England And Wales
11. New Study Finds Blacks Face 38 Percent Higher Stroke Risk

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/15/2018)... ... November 15, 2018 , ... Lisa Vuich MD , medical director of ... Training will take the stage during the 26th World Congress on Anti-Aging Medicine ... leading a CME workshop hosted by Tailor Made Compounding that will highlight ...
(Date:11/14/2018)... ... November 14, 2018 , ... ... President, Account Management at DocASAP, will host a session titled “Patient-centric Care: Closing ... American Medical Group Association (AMGA), the 2018 Institute for Quality Leadership (IQL18) focuses ...
(Date:11/14/2018)... ... 2018 , ... Contrary to what most people think, newspapers, ... hold the honor at a whopping 99.3 percent, according to the Environmental Protection ... the lead battery industry is proudly sharing the impressive sustainability story of lead ...
(Date:11/14/2018)... ... November 14, 2018 , ... The Austin-area sports medicine ... approaches, it’s time to pull out the healthcare plan paperwork to review coverage and ... sponsored by an employer, most people can benefit by taking a few minutes for ...
(Date:11/13/2018)... ... November 13, 2018 , ... People Serving People, the region’s ... Annual Give to the Max Day slated for Thursday, November 15. Last year, People ... to the Max Day. , Give to the Max Day is a project ...
Breaking Medicine News(10 mins):
(Date:11/15/2018)... , ... November 15, 2018 , ... ... Digital Audience of More Than 100 Million Users , The Bluntness Furthers Maven’s ... it has partnered with Maven, a coalition of over 300 exclusive publishers and ...
(Date:11/15/2018)... ... November 15, 2018 , ... ... standards of corporate compliance, Windsor skilled nursing and rehabilitation centers across ... Week. The Society of Corporate Compliance and Ethics & Health Care ...
(Date:11/15/2018)... Ark. (PRWEB) , ... November 15, 2018 , ... ... Management Society of America (CMSA) Conference & Expo, the only case management conference ... at The Mirage in world famous Las Vegas, NV. Industry professionals will convene ...
Breaking Medicine Technology:
Cached News: